azespot 15% cream - Azelaic Acid (15% w/w) medicine

Azespot 15% Cream - Uses, Price, Side Effects

4.6 (16 reviews)
๐Ÿญ e-derma Pharma India Pvt. Ltd. ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is azespot 15% cream used for?

Azespot 15% Cream contains Azelaic Acid, a naturally occurring acid that works by killing acne-causing bacteria and reducing inflammation. It is used to treat mild to moderate acne vulgaris and rosacea. Apply a thin layer to affected areas twice daily, in the morning and evening. It helps unclog pores and reduce redness and swelling.

  • Generic Name: Azelaic Acid
  • Manufacturer: e-derma Pharma India Pvt. Ltd.
  • Form: Allopathy
  • Pregnancy Category: B
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š azespot 15% cream Uses & Benefits

Acne vulgaris, rosacea, melasma.

Off-label uses: Hyperpigmentation, perioral dermatitis.

๐Ÿ“‹ Drug Information

Generic Name(s)Azelaic Acid
Brand NameAziderm 20% Cream
Manufacturere-derma Pharma India Pvt. Ltd.
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassAntimicrobials- Acne
Route of AdministrationTopical
StorageStore at 20-25ยฐC (68-77ยฐF); keep tightly closed.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionApproximately 4% of topically applied azelaic acid is absorbed percutaneously.
DistributionDistributed into the skin layers; systemic distribution is minimal.
Protein BindingNot significantly bound to plasma proteins.
MetabolismPartially metabolized via beta-oxidation to shorter-chain dicarboxylic acids.
Half-LifeApproximately 12 hours (topical application).
ExcretionRenal excretion of metabolites and unchanged drug.
BioavailabilityLow systemic bioavailability (about 4% after topical application).
Onset of Action2-4 weeks for visible improvement in acne.
Peak Plasma TimeNot applicable for topical use; systemic levels are low.
Duration of ActionSustained with regular application.

How It Works

Inhibits microbial protein synthesis and reduces keratinocyte proliferation; anti-inflammatory effects.

Mechanism Steps

1Inhibits bacterial protein synthesis in Propionibacterium acnes
2Reduces keratinocyte proliferation and follicular hyperkeratinization
3Decreases inflammation by inhibiting neutrophil reactive oxygen species

๐Ÿ’ก How to Take azespot 15% cream

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of azespot 15% cream

โœ… Common Side Effects

  • Pruritus
  • Burning
  • Stinging
  • Erythema
  • Dryness

๐Ÿšจ Serious Side Effects

  • Severe allergic reaction (rare)

โš ๏ธ Rare Side Effects

  • Hypopigmentation
  • Contact dermatitis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Isotretinoin Moderate Increased risk of skin irritation
Topical corticosteroids Moderate May reduce efficacy of azelaic acid
Other topical acne treatments Minor Additive skin dryness or irritation

๐Ÿฝ๏ธ Food Interactions

None known.

๐Ÿท Alcohol Interaction

No known interaction.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category B

๐Ÿšซ Contraindications

Hypersensitivity to azelaic acid or any component.

๐Ÿ“Š Monitoring Parameters

Skin irritation, improvement in acne lesions.

๐Ÿคฑ Lactation Safety

Use with caution; not known if excreted in breast milk.

๐Ÿ’Š Overdose Management

Unlikely with topical use; if ingested, symptomatic treatment.

โฐ Missed Dose

Apply as soon as remembered; skip if almost time for next dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for azespot 15% cream

View All

Alternative brands with exact same active ingredient (Azelaic Acid (15% w/w)):

Medical Note: Always consult your doctor before switching medications.

โญ User Reviews

Trusted Reviewer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Trusted Reviewer Jul 10, 2026

Effective and reliable. Worked as expected.

Happy Patient Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Certified Buyer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Verified User Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

๐Ÿ˜Š Was this information helpful?

Browse Medicines A-Z

Search our extensive medical database alphabetically.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory