axinac nano gel - Diclofenac (1.16% w/w) + Linseed Oil (3% w/w) medicine

Axinac Nano Gel: Complete Medicine Guide

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🏭 Axenic Healthcare 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 23, 2026
⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate to well-established for topical NSAIDs in musculoskeletal pain.
Reviewed by
SaathiMed Expert Panel | Oct 23, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction (swelling of face, lips, throat, difficulty breathing)
  • Severe skin rash, blistering, or peeling
  • Signs of gastrointestinal bleeding (black stool, vomiting blood)
  • Chest pain or difficulty breathing
  • Decreased urine output or swelling in legs
  • Yellowing of skin or eyes (jaundice)
  • Persistent or worsening skin irritation

If experiencing severe symptoms, call emergency services immediately.

What is axinac nano gel used for?

This medicine is a topical gel containing diclofenac and linseed oil, used to relieve pain and inflammation in conditions like osteoarthritis and soft tissue injuries. It works by blocking pain-causing chemicals in the body. Apply a thin layer to the affected area 3-4 times daily, or as directed by your doctor.

  • Generic Name: Diclofenac + Linseed Oil
  • Manufacturer: Axenic Healthcare
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 axinac nano gel के बारे में (Hindi Summary)

उपयोग: यह दवा एक टॉपिकल जेल है जिसमें डाइक्लोफेनाक और अलसी का तेल होता है। इसका उपयोग जोड़ों के दर्द, सूजन और मांसपेशियों के दर्द के इलाज के लिए किया जाता है। यह ऑस्टियोआर्थराइटिस, रुमेटॉइड आर्थराइटिस और मोच जैसी समस्याओं में राहत देती है। इसे प्रभावित जगह पर दिन में 3-4 बार लगाएं।

साइड इफेक्ट्स: आम दुष्प्रभावों में त्वचा पर जलन, लालिमा, खुजली या दाने शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी की प्रतिक्रिया हो सकती है जैसे चेहरे, होंठ या गले में सूजन। यदि ऐसा हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को केवल स्वस्थ त्वचा पर लगाएं। आंखों, मुंह या घावों के संपर्क में न आने दें। उपयोग के बाद हाथ धो लें। बिना डॉक्टर की सलाह के 7 दिनों से अधिक उपयोग न करें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 axinac nano gel Uses & Benefits

[{"condition":"Osteoarthritis","description":"Relieves pain and improves joint mobility in knee, hip, and hand osteoarthritis.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Provides local pain relief and reduces inflammation in affected joints.","evidence":"Moderate"},{"condition":"Soft tissue injuries","description":"Used for sprains, strains, and sports injuries to reduce pain and swelling.","evidence":"Well-established"},{"condition":"Localized musculoskeletal pain","description":"Effective for acute muscle pain, back pain, and neck pain.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label for migraine prevention, but evidence is limited.","evidence":"Limited"}]

Primary treatment for: Osteoarthritis

Also treats: Rheumatoid arthritis, Soft tissue injuries, Musculoskeletal pain

📋 Drug Information

Generic Name(s)Diclofenac + Linseed Oil
Brand NameAxinac Nano Gel
ManufacturerAxenic Healthcare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassNonsteroidal Anti-inflammatory Drug (NSAID) + Emollient
Route of AdministrationTopical
StorageStore below 30°C in a cool, dry place. Protect from direct sunlight. Do not freeze.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Apply this medicine only to intact skin and avoid open wounds.
2
Wash your hands thoroughly after applying, unless your hands are the treated area.
3
Do not use this medicine for more than 7 days without consulting a doctor.
4
Avoid covering the treated area with airtight dressings unless directed.
5
If you experience skin irritation, stop use and consult your doctor.
6
Use the lowest effective dose for the shortest duration.
7
Inform your doctor if you are taking oral NSAIDs or blood thinners.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Chronic joint pain
This medicine is commonly prescribed for this.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
✅
Muscle sprain
This medicine can help reduce pain and swelling.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionDiclofenac is absorbed through the skin, but systemic absorption is low compared to oral administration. The extent of absorption depends on the application area, duration, and skin condition. Linseed oil may enhance penetration.
DistributionAfter absorption, diclofenac is highly bound to plasma proteins and distributes mainly to the site of application and surrounding tissues. Systemic distribution is limited.
Protein BindingDiclofenac is approximately 99% bound to plasma proteins, primarily albumin.
MetabolismDiclofenac is metabolized in the liver by cytochrome P450 enzymes, mainly CYP2C9, to several metabolites.
Half-LifeThe elimination half-life of diclofenac from plasma is approximately 1-2 hours, but topical application may result in prolonged local presence.
ExcretionDiclofenac metabolites are excreted primarily in urine (about 65%) and bile/feces (about 35%).
BioavailabilitySystemic bioavailability of topical diclofenac is approximately 5-10% compared to oral dosing, depending on the formulation and application site.
Onset of ActionPain relief may begin within 30 minutes to 1 hour after application, but full anti-inflammatory effects may take several days of regular use.
Peak Plasma TimePeak plasma concentration after topical application is typically reached in 1-2 hours, but levels are much lower than oral dosing.
Duration of ActionThe effect lasts for several hours; application 3-4 times daily is common to maintain relief.

How It Works

This medicine works by inhibiting the cyclooxygenase (COX) enzymes, which are responsible for the production of prostaglandins. Prostaglandins are chemicals that mediate inflammation, pain, and fever. By blocking COX, diclofenac reduces the levels of prostaglandins at the site of application, thereby decreasing inflammation and pain. Linseed oil contains alpha-linolenic acid, an omega-3 fatty acid that may also have anti-inflammatory properties, complementing the effect of diclofenac.

Mechanism Steps

1
Absorption through skin: Diclofenac and linseed oil penetrate the skin and reach the underlying tissues.
2
Inhibition of COX enzymes: Diclofenac inhibits COX-1 and COX-2 enzymes, reducing prostaglandin synthesis.
3
Reduction of inflammation: Decreased prostaglandins lead to reduced inflammation and pain.
4
Analgesic effect: Pain perception is diminished due to reduced sensitization of nerve endings.

💡 How to Take axinac nano gel

Strength: Diclofenac 1.16% w/w + Linseed Oil 3% w/w gel

1Wash your hands before and after applying the gel.
2Clean and dry the affected area.
3Apply a thin layer of the gel to the affected area.
4Gently rub the gel into the skin until it is absorbed.
5Do not cover the area with a bandage or dressing unless instructed by your doctor.
6Avoid contact with eyes, mouth, and other mucous membranes.
7Wash your hands immediately after application, unless your hands are the treated area.

Dosage Information

Adult DosageApply a thin layer of this medicine to the affected area 3 to 4 times daily, or as directed by your doctor. The dose and frequency may vary depending on the condition being treated. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of NSAIDs. Use the lowest effective dose for the shortest duration. Consult a doctor for appropriate dosing.
Renal ImpairmentNo specific dose adjustment is established for topical use. However, use with caution in patients with severe renal impairment. Consult a doctor.
Hepatic ImpairmentNo specific dose adjustment is established for topical use. Use with caution in patients with severe hepatic impairment. Consult a doctor.
Maximum Daily DoseThe maximum daily dose for topical application is not established from available information. Follow your doctor's instructions.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Apply the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not apply a double dose to catch up.

⚠️ Side Effects of axinac nano gel

✅ Common Side Effects

Application site irritation (Common (5-10%))
Usually resolves on its own. If persistent, consult your doctor.
Redness or rash (Common (5-10%))
Discontinue if severe; consult doctor if it worsens.
Itching (Common (5-10%))
Avoid scratching; consult doctor if severe.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of face, lips, throat, or difficulty breathing.
Severe skin reaction (e.g., Stevens-Johnson syndrome) (Very rare (<0.01%))
Stop use and seek immediate medical help if you notice blistering, peeling, or severe rash.
Gastrointestinal bleeding (due to systemic absorption) (Very rare (<0.01%))
Seek immediate medical attention if you notice black stool, vomiting blood, or severe abdominal pain.

⚠️ Rare Side Effects

Photosensitivity reaction
Avoid sun exposure; use sunscreen. Consult doctor if reaction occurs.
Contact dermatitis
Discontinue use and consult a dermatologist.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Ibuprofen Major
Aspirin Major
ACE inhibitors Moderate
Diuretics Moderate
Lithium Moderate
Methotrexate Moderate
Corticosteroids Major
Cyclosporine Moderate
Topical corticosteroids Minor

🚨 Major Interactions

  • Oral NSAIDs (e.g., ibuprofen, naproxen)
  • Anticoagulants (e.g., warfarin)
  • Corticosteroids

⚡ Moderate Interactions

  • Antihypertensives (e.g., ACE inhibitors, diuretics)
  • Lithium
  • Methotrexate

🍷 Alcohol Interaction

No specific interaction is established for topical use. However, alcohol may increase the risk of gastrointestinal bleeding if diclofenac is absorbed systemically. Limit alcohol consumption while using this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Allergy to diclofenac, linseed oil, or any component of the gel.","History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs.","Application on broken, infected, or inflamed skin.","Third trimester of pregnancy.","Children under 14 years of age (unless directed by a doctor)."]

⚠️ Warnings & Precautions

["For external use only. Do not ingest.","Avoid contact with eyes and mucous membranes.","Do not apply to large areas of skin or use under airtight dressings without medical advice.","Discontinue if skin irritation develops.","Consult a doctor if pain persists beyond 7 days or worsens.","Use with caution in elderly patients who may be more susceptible to side effects.","Keep out of reach of children."]

🤱 Lactation Safety

It is not known whether diclofenac passes into breast milk in significant amounts after topical application. Consult your doctor before using this medicine while breastfeeding. Avoid applying to the breast area.

💊 Overdose Management

Overdose from topical application is unlikely. If accidental ingestion occurs, seek immediate medical attention. Symptoms of overdose may include nausea, vomiting, abdominal pain, and drowsiness. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Apply this medicine only to intact skin. Avoid contact with eyes, mucous membranes, or open wounds. Wash your hands thoroughly after applying, unless your hands are the treated area. Do not cover the treated area with airtight dressings unless directed by your doctor. Do not use this medicine for more than 7 days without consulting a doctor. If you are pregnant or breastfeeding, consult your doctor before using this medicine. Do not use this medicine on children under 14 years of age without medical advice. Keep this medicine out of reach of children. Do not use this medicine after the expiry date. If you experience any allergic reaction, stop use and seek medical help immediately.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to side effects of NSAIDs, including skin irritation and systemic effects. Use the lowest effective dose for the shortest duration and monitor closely.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. NSAIDs may affect ovulation and are generally avoided in the third trimester.

🏥 Post-Surgery Considerations

Consult your surgeon before using this medicine after surgery, especially if the surgical site is near the application area. It may be used for post-operative pain under medical supervision.

🦷 Dental Procedures

This medicine is not typically used for dental pain. Consult your dentist for appropriate pain relief after dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce joint stress.
🥗
Regular low-impact exercise like swimming or cycling.
😴
Practice good posture to prevent muscle strain.
💧
Include anti-inflammatory foods in your diet.
🧘
Get adequate sleep to aid recovery.
🌞
Apply heat or cold packs as needed for additional relief.

🏋️ Exercise Considerations

Avoid strenuous exercise or activities that put stress on the affected area until pain and swelling subside. Gentle stretching and range-of-motion exercises may be beneficial, but consult your doctor or physiotherapist.

🥗 Diet Recommendations

Include omega-3 rich foods like fish, flaxseeds, and walnuts.
Reduce processed food intake.
Stay well hydrated.
Eat plenty of fruits and vegetables rich in antioxidants.

💼 Impact on Daily Work & Life

This medicine is applied topically and is unlikely to affect your ability to drive or operate machinery. However, if you experience dizziness or drowsiness (rare), avoid these activities until you feel normal.

🛑 When to Stop This Medicine

Stop using this medicine and consult your doctor if your pain persists beyond 7 days, worsens, or if you experience any severe side effects. Do not stop prescribed treatment without consulting your doctor.

📅 Long-Term Use Effects

Long-term use of topical diclofenac is generally safe, but prolonged use over large areas may increase the risk of systemic side effects such as gastrointestinal and kidney problems. Monitor for skin reactions and consult your doctor if you need to use it for more than 7 days.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain and improve joint function.

Evidence: Well-established
Acupuncture

May help with pain relief in some individuals.

Evidence: Moderate
Heat/cold therapy

Can provide temporary relief from pain and stiffness.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific interactions with vaccines are established for topical diclofenac. However, if you are scheduled for vaccination, inform your healthcare provider about all medicines you are using.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with the prescription label. Keep it in your carry-on luggage if possible. Store it at room temperature, away from direct sunlight. If traveling to a different time zone, continue applying as per your usual schedule. Check customs regulations for carrying topical medications.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old woman with knee osteoarthritis
She started using this medicine as prescribed for her knee pain. After two weeks, she noticed significant improvement in her morning stiffness and could walk more comfortably. She applied it three times a day and experienced only mild skin redness initially, which resolved.
💡 Lesson: Consistent application and adhering to the prescribed frequency can lead to noticeable pain relief in osteoarthritis.
👤 A 40-year-old man with a sports injury
He sprained his ankle while playing football. His doctor recommended this medicine for pain and swelling. He applied it four times daily and used an ice pack. Within three days, the swelling reduced, and he could bear weight with less pain.
💡 Lesson: Topical NSAIDs can be effective for acute soft tissue injuries when combined with rest and ice.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling pain relief within 30 minutes to 1 hour after application, but full anti-inflammatory effects may take several days of regular use.

Q: Can I use this medicine on my face?

A: No, this medicine is not recommended for use on the face. Avoid contact with eyes and mucous membranes.

Q: Is it safe to use during pregnancy?

A: Consult your doctor before using this medicine during pregnancy, especially in the third trimester.

Q: Can I use this medicine with oral painkillers?

A: Consult your doctor before combining with oral NSAIDs, as it may increase the risk of side effects.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for axinac nano gel

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Topical pain gels are completely safe and have no side effects.
    Fact: Topical gels can cause skin irritation and, if absorbed, may have systemic effects. Always use as directed.
  • Myth: You can apply topical gels on any skin wound.
    Fact: Do not apply on broken or infected skin as it can cause irritation and systemic absorption.
  • Myth: More gel means faster relief.
    Fact: Applying more than the recommended amount does not improve efficacy and may increase side effects.

🔄 Alternative Options

Generic Alternatives

  • Diclofenac gel
  • Diclofenac + Linseed Oil gel

Brand Alternatives

  • Voltaren
  • Voveran
  • Diclomol
  • Linseed Oil + Diclofenac gel

📊 Comparison with Similar Medicines

[{"medicine":"Axinac Nano Gel","active_ingredient":"Diclofenac + Linseed Oil","route":"Topical","common_use":"Osteoarthritis, soft tissue injuries"},{"medicine":"Voltaren Gel","active_ingredient":"Diclofenac","route":"Topical","common_use":"Osteoarthritis, soft tissue injuries"},{"medicine":"Ibuprofen Gel","active_ingredient":"Ibuprofen","route":"Topical","common_use":"Muscle pain, sprains"}]

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