axinac nano gel - Diclofenac (1.16% w/w) + Linseed Oil (3% w/w) medicine

Axinac Nano Gel - Uses, Price, Side Effects

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๐Ÿญ Axenic Healthcare ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 27, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 27, 2026

What is axinac nano gel used for?

Axinac Nano Gel is a topical medication containing Diclofenac (1.16% w/w) and Linseed Oil (3% w/w). It is used for relief of pain and inflammation in conditions like arthritis, muscle strains, and joint pain. Diclofenac works by reducing substances that cause pain and swelling, while Linseed Oil provides moisturizing and soothing effects. Apply the gel to the affected area as directed.

  • Generic Name: Diclofenac + Linseed Oil
  • Manufacturer: Axenic Healthcare
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š axinac nano gel Uses & Benefits

Local relief of pain and inflammation in musculoskeletal conditions such as osteoarthritis, rheumatoid arthritis, sprains, strains, and sports injuries.

Off-label uses: Tendinopathy, bursitis, and other soft tissue inflammatory conditions.

๐Ÿ“‹ Drug Information

Generic Name(s)Diclofenac + Linseed Oil
Brand NameAxinac Nano Gel
ManufacturerAxenic Healthcare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassNonsteroidal Anti-inflammatory Drug (NSAID) + Emollient
Route of AdministrationTopical
StorageStore at room temperature (20-25ยฐC); keep tube tightly closed; avoid freezing.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionTopical absorption; systemic absorption is minimal (approximately 6% of applied dose) but can be enhanced by damaged skin or prolonged use.
DistributionDistributes locally to subcutaneous tissues; systemic distribution is low due to limited absorption.
Protein BindingDiclofenac: >99% bound to plasma proteins, primarily albumin.
MetabolismDiclofenac: Hepatic metabolism via CYP2C9 and glucuronidation; linseed oil is not significantly metabolized.
Half-LifeDiclofenac: Approximately 1-2 hours (systemic); topical application results in prolonged local prese
ExcretionDiclofenac: Renal excretion (65% as metabolites, 35% as unchanged drug) and biliary excretion.
BioavailabilityTopical: Low systemic bioavailability (~6% of applied dose).
Onset of ActionWithin 1-2 hours after application.
Peak Plasma TimeNot applicable for topical; local effect peaks within 2-4 hours.
Duration of ActionUp to 8-12 hours per application.

How It Works

Diclofenac inhibits cyclooxygenase (COX-1 and COX-2), reducing prostaglandin synthesis; linseed oil provides emollient and anti-inflammatory effects via omega-3 fatty acids.

Mechanism Steps

1Diclofenac binds to COX-1 and COX-2 enzymes, inhibiting conversion of arachidonic acid to prostaglandins.
2Reduced prostaglandin synthesis decreases inflammation, pain, and fever locally.
3Linseed oil provides omega-3 fatty acids that compete with arachidonic acid, reducing pro-inflammatory eicosanoids.

๐Ÿ’ก How to Take axinac nano gel

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of axinac nano gel

โœ… Common Side Effects

  • Application site reactions (rash, itching, burning, redness)
  • Dry skin
  • Contact dermatitis

๐Ÿšจ Serious Side Effects

  • Gastrointestinal bleeding (rare with topical use)
  • Renal impairment (rare)
  • Severe allergic reactions (anaphylaxis)

โš ๏ธ Rare Side Effects

  • Photosensitivity
  • Stevens-Johnson syndrome
  • Hepatotoxicity

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Aspirin Moderate Increased risk of gastrointestinal bleeding
Methotrexate Major Increased methotrexate toxicity

๐Ÿšจ Major Interactions

  • Warfarin
  • Other NSAIDs
  • Anticoagulants
  • Lithium
  • Methotrexate

โšก Moderate Interactions

  • ACE inhibitors
  • Diuretics
  • Aspirin
  • Corticosteroids

โ„น๏ธ Minor Interactions

  • Antacids
  • Cholestyramine

๐Ÿฝ๏ธ Food Interactions

No significant food interactions for topical use.

๐Ÿท Alcohol Interaction

No direct interaction, but alcohol may increase risk of gastrointestinal bleeding if systemic absorption is high.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity to diclofenac, aspirin, or other NSAIDs; active peptic ulcer; severe renal or hepatic impairment; third trimester of pregnancy; application on broken skin or open wounds.

๐Ÿ“Š Monitoring Parameters

Monitor for skin irritation, allergic reactions, and signs of systemic effects (e.g., gastrointestinal bleeding, renal impairment) with prolonged use.

๐Ÿคฑ Lactation Safety

Limited data; use with caution. Diclofenac is excreted in breast milk in low amounts.

๐Ÿ’Š Overdose Management

Topical overdose unlikely; if ingested accidentally, treat symptomatically; activated charcoal may be considered.

โฐ Missed Dose

Apply as soon as remembered; if near next dose, skip missed dose and resume regular schedule; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 27, 2026

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