Axim O Dry Syrup - Uses, Price, Side Effects, and Dosage
What is axim o dry syrup used for?
Axim O Dry Syrup is a combination antibiotic containing Cefixime (50mg) and Ofloxacin (50mg). It is used to treat bacterial infections such as respiratory tract infections, urinary tract infections, and gastrointestinal infections. Cefixime works by inhibiting bacterial cell wall synthesis, while Ofloxacin inhibits bacterial DNA replication, together providing broad-spectrum antibacterial activity.
- Generic Name: Cefixime + Ofloxacin
- Manufacturer: Uni-Pex Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ axim o dry syrup Uses & Benefits
Respiratory tract infections, urinary tract infections, gastrointestinal infections, skin and soft tissue infections, sexually transmitted infections
Off-label uses: Typhoid fever, Leprosy, Brucellosis
๐ Drug Information
| Generic Name(s) | Cefixime + Ofloxacin |
| Brand Name | Abixim O Tablet |
| Manufacturer | Uni-Pex Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Antibiotic (Cephalosporin + Fluoroquinolone) |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC, protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Cefixime inhibits bacterial cell wall synthesis; Ofloxacin inhibits DNA gyrase and topoisomerase IV
Mechanism Steps
๐ก How to Take axim o dry syrup
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of axim o dry syrup
โ Common Side Effects
- Nausea
- Diarrhea
- Headache
- Dizziness
- Abdominal pain
- Vomiting
- Dyspepsia
๐จ Serious Side Effects
- Tendon rupture
- Peripheral neuropathy
- Severe allergic reactions
- Clostridium difficile colitis
- QT prolongation
- Seizures
- Hepatotoxicity
โ ๏ธ Rare Side Effects
- Blood dyscrasias
- Stevens-Johnson syndrome
- Toxic epidermal necrolysis
- Interstitial nephritis
- Anaphylaxis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| NSAIDs | Moderate | Increased risk of CNS effects |
| Antacids | Moderate | Reduced absorption of Cefixime |
๐จ Major Interactions
- Warfarin
- Antidiabetic agents
- NSAIDs
- Theophylline
- Corticosteroids
โก Moderate Interactions
- Antacids
- Iron supplements
- Zinc supplements
- Sucralfate
- Probenecid
โน๏ธ Minor Interactions
- Caffeine
- Cyclosporine
- Methotrexate
๐ฝ๏ธ Food Interactions
Avoid dairy products, antacids, and iron supplements within 2-4 hours; food may delay absorption
๐ท Alcohol Interaction
Avoid alcohol; may increase CNS effects and hepatotoxicity risk
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to cephalosporins, fluoroquinolones, or any component; history of tendon disorders with fluoroquinolones; pregnancy (ofloxacin); children <18 years (ofloxacin)
๐ Monitoring Parameters
Renal function, hepatic function, blood glucose (in diabetics), signs of tendonitis, CNS effects, QT interval
๐คฑ Lactation Safety
Excreted in breast milk; use with caution
๐ Overdose Management
Supportive care; gastric lavage; monitor renal function and ECG
โฐ Missed Dose
Take as soon as remembered; skip if almost time for next dose; do not double dose