Axi Clav 200mg/125mg Tablet - Uses, Price, Side Effects
What is axi clav 200mg/125mg tablet used for?
Axi Clav 200mg/125mg Tablet is a combination antibiotic used to treat bacterial infections like respiratory tract infections, urinary tract infections, and skin infections. It works by stopping the growth of bacteria and preventing resistance.
- Generic Name: Cefixime + Potassium Clavulanate
- Manufacturer: Axis Life Science Pvt Ltd
- Form: Allopathy
- Pregnancy Category: B
- Prescription Required: Yes
๐ axi clav 200mg/125mg tablet Uses & Benefits
Upper and lower respiratory tract infections, urinary tract infections, otitis media, sinusitis, gonorrhea, skin and soft tissue infections.
Off-label uses: Prophylaxis in surgery, Lyme disease, Typhoid fever
๐ Drug Information
| Generic Name(s) | Cefixime + Potassium Clavulanate |
| Brand Name | Axi Clav 200mg/125mg Tablet |
| Manufacturer | Axis Life Science Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cephalosporin antibiotic + Beta-lactamase inhibitor |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC; protect from moisture and light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Cefixime inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs). Potassium clavulanate irreversibly inhibits beta-lactamases, protecting cefixime from degradation.
Mechanism Steps
๐ก How to Take axi clav 200mg/125mg tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of axi clav 200mg/125mg tablet
โ Common Side Effects
- Diarrhea
- Nausea
- Vomiting
- Abdominal pain
- Headache
- Rash
๐จ Serious Side Effects
- Pseudomembranous colitis
- Stevens-Johnson syndrome
- Anaphylaxis
- Seizures
- Hemolytic anemia
โ ๏ธ Rare Side Effects
- Hepatitis
- Interstitial nephritis
- Thrombocytopenia
- Agranulocytosis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Methotrexate | Moderate | Increased methotrexate toxicity |
| Probenecid | Moderate | Reduced excretion of cefixime |
๐จ Major Interactions
- Warfarin
- Methotrexate
- Probenecid
- Live typhoid vaccine
- BCG vaccine
โก Moderate Interactions
- Oral contraceptives
- Loop diuretics
- Aminoglycosides
- Anticoagulants
โน๏ธ Minor Interactions
- Antacids
- Iron supplements
- Zinc supplements
๐ฝ๏ธ Food Interactions
Food delays absorption; take with food to reduce GI upset.
๐ท Alcohol Interaction
Avoid alcohol; may cause disulfiram-like reaction (flushing, headache, nausea).
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to cephalosporins or beta-lactamase inhibitors; history of anaphylaxis to penicillins.
๐ Monitoring Parameters
Renal function, liver function, CBC, signs of superinfection, bleeding time.
๐คฑ Lactation Safety
Caution; excreted in breast milk in small amounts.
๐ Overdose Management
Gastric lavage, supportive care; hemodialysis may enhance elimination.
โฐ Missed Dose
Take as soon as remembered; skip if almost time for next dose; do not double.