Axetin Tz 2000mg/250mg Injection - Uses, Price, Side Effects
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
What is axetin tz 2000mg/250mg injection used for?
Axetin TZ 2000mg/250mg Injection is a combination antibiotic containing Ceftriaxone (2000mg) and Tazobactam (250mg). It is used to treat severe bacterial infections such as pneumonia, urinary tract infections, and intra-abdominal infections. Ceftriaxone kills bacteria by inhibiting cell wall synthesis, while Tazobactam prevents bacterial resistance by inhibiting beta-lactamase enzymes. This injection is administered intravenously or intramuscularly under medical supervision.
- Generic Name: Ceftriaxone + Tazobactam
- Manufacturer: Nootan Pharmaceuticals
- Form: Allopathy
- Pregnancy Category: Category A
- Prescription Required: Yes
💊 axetin tz 2000mg/250mg injection Uses & Benefits
Treatment of infections caused by susceptible organisms: respiratory tract, urinary tract, skin and soft tissue, intra-abdominal, septicemia, meningitis.
Off-label uses: Lyme disease, Pelvic inflammatory disease, Gonorrhea
📋 Drug Information
| Generic Name(s) | Ceftriaxone + Tazobactam |
| Brand Name | Accutaz AS |
| Manufacturer | Nootan Pharmaceuticals |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Antibiotic (Cephalosporin + Beta-lactamase inhibitor) |
| Route of Administration | Intravenous (IV) or Intramuscular (IM) |
| Storage | Store at 20-25°C; protect from light; reconstituted solution stable for 24 hours at room temperature or 3 days refrigerated. |
| Shelf Life | As per manufacturer |
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Ceftriaxone inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs). Tazobactam inhibits beta-lactamases, preventing degradation of ceftriaxone.
Mechanism Steps
💡 How to Take axetin tz 2000mg/250mg injection
Follow your doctor's prescription exactly.
Dosage Timeline
⚠️ Side Effects of axetin tz 2000mg/250mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Alcohol | Moderate | Increased risk of side effects |
| Probenecid | Moderate | Decreased excretion of ceftriaxone |
🚨 Major Interactions
- Warfarin
- Aminoglycosides
- Loop diuretics
- Probenecid
⚡ Moderate Interactions
- Oral contraceptives
- Live vaccines
- BCG vaccine
🍷 Alcohol Interaction
May cause disulfiram-like reaction (rare with ceftriaxone)
🛡️ Safety & Warnings
🚫 Contraindications
Hypersensitivity to cephalosporins or beta-lactamase inhibitors; hyperbilirubinemic neonates (ceftriaxone displaces bilirubin).
🤱 Lactation Safety
Excreted in breast milk in low amounts; generally considered compatible.
💊 Overdose Management
Supportive care; hemodialysis may remove ceftriaxone but not tazobactam.
⏰ Missed Dose
Administer as soon as remembered; if near next dose, skip missed dose; do not double dose.