Avomira 25mg Tablet ER (Mirabegron): Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Severe headache with visual changes or nosebleeds
- Inability to urinate or painful urination
- Swelling of the face, lips, tongue, or throat
- Difficulty breathing or rash with blisters
- Yellowing of the skin or eyes, dark urine, or abdominal pain
- Chest pain or irregular heartbeat
- Severe dizziness or fainting
If experiencing severe symptoms, call emergency services immediately.
What is avomira 25mg tablet er used for?
This medicine is an extended-release tablet containing Mirabegron 25 mg, used to treat overactive bladder symptoms such as urgency, frequency, and urge incontinence. It works by relaxing the bladder muscle to increase bladder capacity. It is taken once daily, with or without food, and should be swallowed whole.
- Generic Name: Mirabegron
- Manufacturer: Micro Labs Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 avomira 25mg tablet er के बारे में (Hindi Summary)
उपयोग: यह दवा मिराबेग्रॉन 25 मिलीग्राम एक्सटेंडेड-रिलीज़ टैबलेट के रूप में उपलब्ध है और मुख्य रूप से अति सक्रिय मूत्राशय (ओवरएक्टिव ब्लैडर) के इलाज के लिए इस्तेमाल की जाती है। अति सक्रिय मूत्राशय में बार-बार पेशाब आना, अचानक तेज इच्छा होना और कभी-कभी पेशाब का रिसना जैसी समस्याएं होती हैं। यह दवा मूत्राशय की मांसपेशियों को आराम देकर मूत्राशय की क्षमता बढ़ाती है और अनियंत्रित संकुचन को कम करती है। यह दवा उन वयस्कों के लिए है जिन्हें अन्य दवाओं से लाभ नहीं हुआ है। इसे रोज एक बार लेना होता है, भोजन के साथ या बिना। ध्यान रखें कि यह दवा बच्चों, गर्भवती महिलाओं और गंभीर उच्च रक्तचाप या गंभीर जिगर की बीमारी वाले लोगों के लिए नहीं है।
साइड इफेक्ट्स: आम दुष्प्रभावों में रक्तचाप में वृद्धि, सिरदर्द, मूत्र मार्ग में संक्रमण, कब्ज और मुंह सूखना शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभावों में बहुत अधिक रक्तचाप बढ़ना, पेशाब करने में कठिनाई, और एलर्जी प्रतिक्रियाएं जैसे चेहरे, होंठ या गले में सूजन शामिल हैं। यदि आपको कोई असामान्य लक्षण दिखे, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को शुरू करने से पहले अपने डॉक्टर को अपनी उच्च रक्तचाप, जिगर या गुर्दे की बीमारी, या किसी भी हृदय रोग के बारे में बताएं। इस दवा को लेते समय नियमित रूप से रक्तचाप की जांच कराएं। टैबलेट को चबाएं या तोड़ें नहीं, इसे पूरा निगल लें। इसे हर दिन एक ही समय पर लें। शराब का सेवन सीमित करें क्योंकि इससे चक्कर आ सकते हैं। यदि आपको कोई खुराक छूट जाए, तो याद आते ही ले लें, लेकिन अगली खुराक का समय नजदीक हो तो छोड़ दें। डॉक्टर की सलाह के बिना दवा बंद न करें।
💊 avomira 25mg tablet er Uses & Benefits
[{"condition":"Overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency","description":"This medicine is used to treat the symptoms of overactive bladder, helping to reduce the number of sudden urges to urinate and episodes of accidental leakage.","evidence":"Well-established"},{"condition":"Neurogenic detrusor overactivity","description":"Sometimes prescribed for bladder dysfunction due to neurological conditions, but this is not a primary approved use.","evidence":"Limited"}]
Off-label uses: [{"condition":"Bladder outlet obstruction","description":"Rarely used off-label to improve bladder emptying in certain patients, but evidence is limited.","evidence":"Limited"}]
Primary treatment for: Overactive bladder
Also treats: Urge urinary incontinence, Urinary frequency, Nocturia
📋 Drug Information
| Generic Name(s) | Mirabegron |
| Brand Name | Avomira 25mg Tablet ER |
| Manufacturer | Micro Labs Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | UROLOGY |
| Action Class | Selective beta 3-adrenoceptor agonist (Bladder) |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep the tablets in their original container, tightly closed, and protect from moisture and light. Do not refrigerate. |
| Shelf Life | The shelf life of this medicine is typically 24 months from the date of manufacture. Check the expiry date on the packaging before use. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by selectively stimulating beta-3 adrenergic receptors located in the detrusor muscle of the urinary bladder. When these receptors are activated, the detrusor muscle relaxes, which increases bladder capacity and reduces the frequency of involuntary contractions that cause urgency and leakage. This action helps to control the symptoms of overactive bladder without affecting other types of adrenergic receptors to a significant degree.
Mechanism Steps
💡 How to Take avomira 25mg tablet er
Strength: Extended-release tablet, 25 mg
Dosage Information
| Adult Dosage | The recommended starting dose of this medicine for adults is 25 mg once daily, taken with or without food. Based on individual response and tolerability, the dose may be increased to 50 mg once daily after 4 to 8 weeks. For patients with severe renal impairment or moderate hepatic impairment, the maximum dose is 25 mg once daily. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | No overall differences in safety or effectiveness have been observed between elderly patients (65 years and older) and younger adults. However, because elderly patients may have reduced renal function, dose selection should be cautious and renal function should be monitored. |
| Renal Impairment | For patients with mild to moderate renal impairment (creatinine clearance 30-89 mL/min), no dose adjustment is necessary. For patients with severe renal impairment (creatinine clearance 15-29 mL/min), the dose should not exceed 25 mg once daily. This medicine is not recommended for patients with end-stage renal disease (creatinine clearance less than 15 mL/min or on dialysis). |
| Hepatic Impairment | For patients with mild hepatic impairment (Child-Pugh Class A), no dose adjustment is necessary. For patients with moderate hepatic impairment (Child-Pugh Class B), the dose should not exceed 25 mg once daily. This medicine is not recommended for patients with severe hepatic impairment (Child-Pugh Class C). |
| Maximum Daily Dose | The maximum recommended daily dose is 50 mg once daily for patients with normal renal and hepatic function. For patients with severe renal impairment or moderate hepatic impairment, the maximum daily dose is 25 mg. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of avomira 25mg tablet er
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Digoxin | Major | |
| Warfarin | Major | |
| Metoprolol | Major | |
| Ketoconazole | Moderate | |
| Rifampicin | Moderate | |
| Cyclosporine | Moderate | |
| Antacids | Minor | |
| H2 blockers | Minor | |
| Grapefruit juice | Moderate | |
| Alcohol | Moderate |
🚨 Major Interactions
- Digoxin
- Warfarin
- Metoprolol
⚡ Moderate Interactions
- Ketoconazole
- Rifampicin
- Cyclosporine
🍷 Alcohol Interaction
Alcohol may enhance the blood pressure-lowering effects of this medicine and increase the risk of dizziness or fainting. It is advisable to limit or avoid alcohol while taking this medicine, especially when starting treatment or adjusting the dose.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to Mirabegron or any component of the formulation","Severe uncontrolled hypertension (systolic blood pressure ≥180 mmHg or diastolic ≥110 mmHg)","Severe hepatic impairment (Child-Pugh Class C)","End-stage renal disease or dialysis","Use in children"]
⚠️ Warnings & Precautions
["This medicine can increase blood pressure. Monitor blood pressure regularly, especially in patients with hypertension.","Use with caution in patients with bladder outlet obstruction or those taking antimuscarinic drugs, as urinary retention may occur.","Patients with severe renal impairment (creatinine clearance less than 30 mL/min) should not take this medicine.","Patients with moderate hepatic impairment should not exceed a dose of 25 mg once daily.","This medicine may cause dizziness; avoid driving or operating machinery until you know how it affects you.","Do not crush, chew, or break the extended-release tablet; swallow it whole.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding."]
🤱 Lactation Safety
It is not known whether this medicine is excreted in human breast milk. Because many drugs are excreted in human milk, caution should be exercised when this medicine is administered to a breastfeeding woman. Consult your doctor to weigh the benefits and risks.
💊 Overdose Management
There is limited experience with overdose of this medicine. In case of overdose, symptomatic and supportive treatment is recommended. Monitor blood pressure and heart rate. Contact a poison control center or emergency department immediately if you suspect an overdose.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.
Additional Safety Advice
Before starting this medicine, tell your doctor if you have high blood pressure, liver or kidney disease, or any heart condition. Your blood pressure should be checked regularly while taking this medicine, especially if you already have hypertension. Do not crush, chew, or break the extended-release tablet; swallow it whole with water. Take it at the same time each day, with or without food. Avoid drinking alcohol excessively, as it may worsen dizziness or low blood pressure. If you miss a dose, take it as soon as you remember unless it is almost time for your next dose; do not double the dose. Do not stop taking this medicine without consulting your doctor, as your symptoms may return. Keep all appointments for monitoring, and inform your doctor about all other medicines you are taking, including over-the-counter drugs and herbal supplements.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the blood pressure-increasing effects of this medicine. Regular monitoring of blood pressure and renal function is advised. Dose adjustment may be necessary based on renal function. Falls due to dizziness should be monitored.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss with your doctor before starting or continuing this medicine. There is limited data on its safety in pregnancy. Your doctor may consider alternative treatments.
🏥 Post-Surgery Considerations
If you are undergoing surgery, inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be temporarily stopped before surgery due to its effects on blood pressure and heart rate. Follow your doctor's instructions.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. It is generally safe for dental procedures, but if you are having surgery, your dentist may consult with your doctor. Maintain good oral hygiene to prevent dry mouth-related issues.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Regular exercise is beneficial, but avoid high-impact activities that may increase intra-abdominal pressure and worsen urinary symptoms. Low-impact exercises like walking, swimming, and yoga are recommended. If you experience dizziness while exercising, stop and consult your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It should not interfere with most desk jobs. If your work involves frequent bathroom breaks, the medicine may help reduce urgency and improve productivity.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects such as severe hypertension, urinary retention, or allergic reactions, stop the medicine and seek immediate medical attention. Your doctor may adjust the dose or switch to an alternative treatment.
📅 Long-Term Use Effects
Long-term use of this medicine is generally well-tolerated. However, regular monitoring of blood pressure and renal function is recommended. Some patients may experience persistent dry mouth or constipation. There is no evidence of tolerance or dependence. Periodic review with your doctor is advised to ensure continued benefit and to monitor for any rare adverse effects.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Scheduled voiding and delaying urination to increase bladder capacity.
Evidence: Well-establishedStrengthening pelvic floor muscles to improve bladder control.
Evidence: Well-establishedMild electrical pulses to stimulate nerves that control bladder function.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. You can receive vaccinations as scheduled. Inform your healthcare provider about all medicines you are taking before any vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from moisture. If crossing time zones, continue taking your dose at the same local time as usual; no adjustment is typically needed for once-daily dosing. Check customs regulations for carrying prescription medicines to your destination.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start noticing improvement in symptoms within 1 to 2 weeks, but it may take up to 4 to 8 weeks for the full effect. Continue taking it as prescribed.
A: Yes, this medicine can be taken with or without food. However, avoid taking it with large amounts of grapefruit juice.
A: If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. Do not double the dose.
A: There is limited information about its safety in pregnancy. Consult your doctor to weigh the benefits and risks.
A: Do not stop without consulting your doctor. Your symptoms may return if you stop abruptly.
🤔 Common Patient Concerns
🔄 Substitutes for avomira 25mg tablet er
View AllAlternative brands with exact same active ingredient:
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mirajet 25mg tablet erLabcorp India Pvt Ltd ₹59.00 77.9% CHEAPER
-
miratas 25 tablet erIntas Pharmaceuticals Ltd ₹180.00 32.6% CHEAPER
-
mbgron 25 tablet erCare Formulation Labs Pvt Ltd ₹182.81 31.6% CHEAPER
-
blador 25mg tablet erKoye Pharmaceuticals Pvt ltd ₹187.50 29.8% CHEAPER
-
mirafast 25mg tabletFuture Pharma Pvt Ltd ₹201.56 24.5% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a cure for overactive bladder.
Fact: This medicine helps manage symptoms but does not cure the condition. It must be taken regularly to maintain effect. - Myth: This medicine works immediately.
Fact: It may take several days to weeks to notice improvement in symptoms. - Myth: This medicine can be taken with grapefruit juice without any issues.
Fact: Grapefruit juice can increase the levels of this medicine in your body, potentially increasing side effects. It is best to avoid large amounts. - Myth: This medicine is safe for everyone with overactive bladder.
Fact: It is not suitable for people with severe uncontrolled hypertension, severe liver disease, or end-stage kidney disease.
🔄 Alternative Options
Generic Alternatives
- Mirabegron
Brand Alternatives
- Myrbetriq
- Betmiga