Avim C 500mg/500mg Injection - Uses, Price, Side Effects
What is avim c 500mg/500mg injection used for?
Avim C 500mg/500mg Injection contains Imipenem (500mg) and Cilastatin (500mg). It is a broad-spectrum antibiotic used to treat severe bacterial infections such as pneumonia, intra-abdominal infections, and complicated urinary tract infections. Imipenem kills bacteria by inhibiting cell wall synthesis, while Cilastatin prevents its breakdown in the kidneys, enhancing efficacy.
- Generic Name: Imipenem + Cilastatin
- Manufacturer: Arvincare Pharma
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ avim c 500mg/500mg injection Uses & Benefits
Treatment of serious infections including intra-abdominal, urinary tract, respiratory tract, skin and soft tissue, bone and joint, and septicemia
Off-label uses: Febrile neutropenia, Empiric therapy in critically ill patients
๐ Drug Information
| Generic Name(s) | Imipenem + Cilastatin |
| Brand Name | Avim C 500mg/500mg Injection |
| Manufacturer | Arvincare Pharma |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Carbapenem antibiotic with renal dehydropeptidase inhibitor |
| Route of Administration | Intravenous |
| Storage | Store at 20-25ยฐC; protect from freezing |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs)
Mechanism Steps
๐ก How to Take avim c 500mg/500mg injection
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of avim c 500mg/500mg injection
โ Common Side Effects
- Nausea
- Vomiting
- Diarrhea
- Rash
- Phlebitis at injection site
๐จ Serious Side Effects
- Seizures
- Clostridioides difficile colitis
- Anaphylaxis
- Stevens-Johnson syndrome
โ ๏ธ Rare Side Effects
- Agranulocytosis
- Hemolytic anemia
- Interstitial nephritis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Valproic Acid | Major | Decreased valproic acid levels, risk of seizures |
| Ganciclovir | Major | Increased risk of seizures |
| Probenecid | Moderate | Increased imipenem levels |
๐จ Major Interactions
- Valproic acid
- Ganciclovir
- Probenecid
โก Moderate Interactions
- Methotrexate
- Cyclosporine
- Warfarin
โน๏ธ Minor Interactions
- Oral contraceptives
๐ฝ๏ธ Food Interactions
No significant food interactions
๐ท Alcohol Interaction
Avoid alcohol; may increase risk of disulfiram-like reaction
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to imipenem, cilastatin, or other carbapenems; severe hypersensitivity to beta-lactams
๐ Monitoring Parameters
Renal function, liver function, CBC, signs of superinfection
๐คฑ Lactation Safety
Caution; excreted in breast milk in low amounts
๐ Overdose Management
Supportive care; hemodialysis may help remove imipenem/cilastatin
โฐ Missed Dose
Administer as soon as remembered; do not double dose