Aleev 125mg Syrup (Levofloxacin): Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Sudden pain, swelling, or inability to move a joint (possible tendon rupture).
- Numbness, tingling, or burning in hands or feet (peripheral neuropathy).
- Seizures, confusion, or hallucinations.
- Severe allergic reaction: difficulty breathing, swelling of face or throat, severe rash.
- Yellowing of skin or eyes, dark urine, or severe abdominal pain (liver damage).
- Irregular heartbeat, palpitations, or fainting.
- Severe or bloody diarrhea.
If experiencing severe symptoms, call emergency services immediately.
What is aviflox suspension used for?
This medicine is a levofloxacin syrup used to treat bacterial infections such as pneumonia, sinusitis, and urinary tract infections. It works by killing bacteria and is taken orally, usually once daily. Complete the full course as prescribed.
- Generic Name: Levofloxacin
- Manufacturer: Avalanche Pharmaceuticals
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 aviflox suspension के बारे में (Hindi Summary)
उपयोग: यह दवा लेवोफ्लोक्सासिन सिरप है, जिसका उपयोग बैक्टीरियल संक्रमण जैसे निमोनिया, साइनसाइटिस, मूत्र मार्ग संक्रमण और त्वचा संक्रमण के इलाज के लिए किया जाता है। यह बैक्टीरिया को मारकर काम करती है और आमतौर पर दिन में एक बार मुँह से ली जाती है। डॉक्टर के बताए अनुसार पूरा कोर्स पूरा करें।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, दस्त, सिरदर्द, चक्कर आना और नींद न आना शामिल हैं। गंभीर दुष्प्रभावों में टेंडन टूटना, तंत्रिका क्षति, दौरे और एलर्जी प्रतिक्रियाएँ हो सकती हैं। कोई भी असामान्य लक्षण होने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। एंटासिड, आयरन या जिंक सप्लीमेंट के साथ लेने से बचें। पर्याप्त पानी पिएँ। चक्कर आने पर वाहन न चलाएँ। गुर्दे की बीमारी, मधुमेह या टेंडन विकार के इतिहास के बारे में डॉक्टर को बताएं।
💊 aviflox suspension Uses & Benefits
[{"condition":"Community-acquired pneumonia","description":"Used to treat bacterial pneumonia caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Acute bacterial sinusitis","description":"Effective against sinus infections caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Acute bacterial exacerbation of chronic bronchitis","description":"Used to treat flare-ups of chronic bronchitis due to bacterial infection.","evidence":"Well-established"},{"condition":"Urinary tract infections","description":"Treats complicated and uncomplicated UTIs caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Used for uncomplicated skin infections caused by susceptible bacteria.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Tuberculosis (as part of combination therapy)","description":"Sometimes used off-label as a second-line agent in multidrug-resistant tuberculosis.","evidence":"Limited"},{"condition":"Prostatitis","description":"May be used off-label for chronic bacterial prostatitis.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Community-acquired pneumonia, Acute bacterial sinusitis, Urinary tract infections, Skin infections
📋 Drug Information
| Generic Name(s) | Levofloxacin |
| Brand Name | Alevo 500 Tablet |
| Manufacturer | Avalanche Pharmaceuticals |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | OPHTHAL |
| Action Class | Quinolones/ Fluroquinolones |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep the bottle tightly closed. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Levofloxacin is included in the WHO Model List of Essential Medicines for the treatment of certain bacterial infections. |
| ICMR Guideline | ICMR guidelines recommend levofloxacin for the treatment of community-acquired pneumonia and other susceptible bacterial infections, with caution due to antimicrobial resistance. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Levofloxacin inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes required for DNA replication, transcription, repair, and recombination. This inhibition leads to double-strand DNA breaks and ultimately bacterial cell death.
Mechanism Steps
💡 How to Take aviflox suspension
Strength: Levofloxacin 125 mg per 5 mL syrup
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 250 mg to 750 mg once daily, depending on the type and severity of infection. The duration of treatment varies from 3 to 14 days. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may require dose adjustment based on renal function. Use with caution due to increased risk of tendon rupture and CNS effects. |
| Renal Impairment | Dose adjustment is required in patients with renal impairment. For creatinine clearance 20-49 mL/min, the usual dose is 250 mg every 24 hours; for 10-19 mL/min, 250 mg every 48 hours. Consult your doctor for precise dosing. |
| Hepatic Impairment | No dosage adjustment is required for hepatic impairment as levofloxacin is primarily excreted unchanged by the kidneys. |
| Maximum Daily Dose | 750 mg per day |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of aviflox suspension
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Antacids | Major | |
| Warfarin | Major | |
| NSAIDs | Major | |
| Theophylline | Major | |
| Amiodarone | Major | |
| Corticosteroids | Moderate | |
| Oral hypoglycemics | Moderate | |
| Probenecid | Moderate | |
| Caffeine | Minor | |
| Cyclosporine | Minor |
🚨 Major Interactions
- Antacids, sucralfate, iron, zinc
- Warfarin
- NSAIDs
- Theophylline
- Antiarrhythmics (e.g., amiodarone, sotalol)
⚡ Moderate Interactions
- Corticosteroids
- Oral hypoglycemics
- Probenecid
🍷 Alcohol Interaction
Alcohol may increase the risk of central nervous system side effects such as dizziness and drowsiness. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to levofloxacin or other fluoroquinolones","Myasthenia gravis","Pregnancy (unless benefit outweighs risk)","Breastfeeding (unless benefit outweighs risk)","Children under 18 years (unless specifically indicated)"]
⚠️ Warnings & Precautions
["Tendon rupture, including Achilles tendon, can occur; risk increased in elderly, corticosteroid users, and organ transplant recipients.","Peripheral neuropathy may occur and can be irreversible.","Central nervous system effects including seizures, confusion, and hallucinations have been reported.","May exacerbate muscle weakness in patients with myasthenia gravis.","Avoid excessive sun exposure; photosensitivity reactions can occur.","May cause blood sugar disturbances; monitor closely in diabetics.","Not recommended for children under 18 except for specific indications."]
🤱 Lactation Safety
Levofloxacin is excreted in breast milk. It is not recommended during breastfeeding unless clearly needed. Consult your doctor.
💊 Overdose Management
In case of overdose, seek immediate medical attention. Treatment is symptomatic and supportive. Adequate hydration should be maintained. Levofloxacin is not effectively removed by hemodialysis or peritoneal dialysis.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop early. Avoid taking antacids, iron, or zinc supplements within 2 hours before or after this medicine. Drink plenty of fluids. Avoid excessive sunlight. Do not drive or operate machinery if you feel dizzy. Inform your doctor if you have kidney problems, diabetes, or a history of tendon disorders. Do not share this medicine with others.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of tendon rupture, kidney problems, and CNS effects. Dose adjustment may be needed based on renal function. Use with caution.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before taking this medicine. It is not recommended during pregnancy unless clearly needed.
🏥 Post-Surgery Considerations
Inform your surgeon if you are taking this medicine before surgery, as it may interact with anesthetics and increase the risk of tendon rupture.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine. It may interact with certain antibiotics used in dentistry. No specific precautions are usually needed.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or heavy lifting while taking this medicine, as it may increase the risk of tendon rupture. Light activities like walking are generally safe. Consult your doctor before resuming intense exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness. Avoid driving or operating heavy machinery until you know how it affects you. It is advisable to take it when you can rest if you experience side effects.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor, even if you feel better. Stopping early can lead to recurrence of infection and antibiotic resistance. If you experience serious side effects, contact your doctor immediately.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to bacterial resistance, fungal overgrowth, and rare but serious effects like tendon damage, nerve damage, and liver injury. Regular monitoring of kidney and liver function may be required. Use only as prescribed for the shortest duration necessary.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Depending on the infection, other antibiotics like amoxicillin or azithromycin may be used.
Evidence: Well-establishedRest, hydration, and fever control can complement antibiotic therapy.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you are due for any live vaccines, consult your doctor as antibiotics may affect the immune response.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from direct sunlight. If traveling across time zones, adjust dosing times gradually. Check customs regulations for carrying prescription medicines. Keep it in your carry-on luggage.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 2-3 days, but you must complete the full course as prescribed.
A: Yes, you can take it with or without food. If it upsets your stomach, take it with a meal.
A: Avoid antacids, iron, zinc supplements, and excessive sunlight. Also avoid alcohol.
🤔 Common Patient Concerns
🔄 Substitutes for aviflox suspension
View AllAlternative brands with exact same active ingredient:
-
leoquin 125mg suspensionZoic Lifesciences ₹39.00 7.1% CHEAPER
-
mlevo 125mg suspensionMoraceae Pharmaceuticals Pvt Ltd ₹54.49 29.7% COSTLIER
-
levofun 125mg syrupSehat Pharma Pvt Ltd ₹64.00 52.4% COSTLIER
-
mslevo suspensionMPS Life Sciences Pvt Ltd ₹64.90 54.5% COSTLIER
-
levoke oral suspensionLewis Bioserch Pharma Pvt Ltd ₹66.40 58.1% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure viral infections like the flu.
Fact: This medicine is an antibiotic and only works against bacterial infections. It is ineffective against viruses. - Myth: You can stop taking this medicine once you feel better.
Fact: You must complete the full course as prescribed to prevent bacterial resistance and recurrence of infection. - Myth: This medicine is safe for everyone.
Fact: It is not recommended for children under 18, pregnant women, or those with myasthenia gravis unless specifically advised by a doctor.
🔄 Alternative Options
Generic Alternatives
- Levofloxacin 125 mg/5 mL oral solution
Brand Alternatives
- Levofloxacin oral solution (various brands)