autic 250mg injection - Uses, Price, Side Effects & Substitutes
What is autic 250mg injection used for?
Acivir 400 DT Tablet (Acyclovir) is used to treat ANTI INFECTIVES. It contains Acyclovir (250mg), which Acyclovir is converted to acyclovir monophosphate by viral thymidine kinase, the. Always consult your doctor before use. Take as prescribed.
- Generic Name: Acyclovir
- Manufacturer: H & I Critical Care
- Form: Allopathy
- Pregnancy Category: B
- Prescription Required: Yes
๐ autic 250mg injection Uses & Benefits
Herpes simplex infections (genital, oral, encephalitis), varicella-zoster (chickenpox, shingles).
Off-label uses: Herpes simplex prophylaxis in immunocompromised, EBV infection
๐ Drug Information
| Generic Name(s) | Acyclovir |
| Brand Name | Acivir 400 DT Tablet |
| Manufacturer | H & I Critical Care |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Antiviral (Non-HIV) drugs |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Acyclovir is converted to acyclovir monophosphate by viral thymidine kinase, then to triphosphate by cellular kinases, which inhibits viral DNA polymerase and incorporates into viral DNA, causing chain termination.
Mechanism Steps
๐ก How to Take autic 250mg injection
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of autic 250mg injection
โ Common Side Effects
- Nausea
- Diarrhea
- Headache
- Dizziness
- Fatigue
๐จ Serious Side Effects
- Acute renal failure
- Neurotoxicity (confusion, hallucinations, seizures)
- Thrombotic thrombocytopenic purpura/hemolytic uremic syndrome (TTP/HUS)
โ ๏ธ Rare Side Effects
- Hepatitis
- Stevens-Johnson syndrome
- Anaphylaxis
- Leukopenia
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Probenecid | Major | Reduced renal clearance of acyclovir, increased plasma levels and toxicity risk. |
| Cimetidine | Major | Increased acyclovir AUC and half-life. |
| Mycophenolate mofetil | Major | Increased plasma levels of both drugs; monitor for toxicity. |
| Tenofovir | Moderate | Additive nephrotoxicity risk. |
| Aminoglycosides | Moderate | Increased risk of nephrotoxicity. |
| Cyclosporine | Moderate | Increased nephrotoxicity risk. |
| Tacrolimus | Moderate | Increased nephrotoxicity risk. |
| Zidovudine | Minor | Possible increased drowsiness. |
| Interferon | Minor | Possible additive antiviral effect. |
๐จ Major Interactions
- Probenecid
- Cimetidine
- Mycophenolate mofetil
โก Moderate Interactions
- Tenofovir
- Aminoglycosides
- Cyclosporine
- Tacrolimus
โน๏ธ Minor Interactions
- Zidovudine
- Interferon
๐ฝ๏ธ Food Interactions
No significant food interactions; may be taken with or without food.
๐ท Alcohol Interaction
No known interaction; however, alcohol may exacerbate side effects like dizziness.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to acyclovir or valacyclovir.
๐ Monitoring Parameters
Renal function (especially in elderly or high-dose therapy); hydration status.
๐คฑ Lactation Safety
Caution; acyclovir is excreted in breast milk but considered compatible with breastfeeding.
๐ Overdose Management
Supportive care; hemodialysis may enhance elimination.
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose. Do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for autic 250mg injection
View AllAlternative brands with exact same active ingredient (Acyclovir (250mg)):
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iqbavir 250mg injectionSuncure Lifescience Pvt Ltd โน232.50 30.7% CHEAPER
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axovir 250mg injectionSamarth Life Sciences Pvt Ltd โน254.90 24% CHEAPER
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Medical Note: Always consult your doctor before switching medications.