atm lx 500 mg/500 mg tablet - Levofloxacin (500mg) + Azithromycin (500mg) medicine

Azibact L 500 mg/500 mg Tablet: Complete Medicine Guide

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🏭 Indoco Remedies Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 25, 2026
⚠️ Hepatotoxicity Risk 🤰 Pregnancy Category Levofloxacin and azithromycin should be used during pregnancy only if the potential benefit justifies the potential risk. Consult your doctor. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Established for individual components; limited for the fixed-dose combination.
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Tendon pain or swelling
  • Numbness or tingling in hands or feet
  • Palpitations or fainting

If experiencing severe symptoms, call emergency services immediately.

What is atm lx 500 mg/500 mg tablet used for?

This medicine is a combination antibiotic containing Levofloxacin 500 mg and Azithromycin 500 mg. It is used to treat serious bacterial infections under a doctor's supervision. It works by killing bacteria through two different mechanisms. It should not be used for viral infections.

  • Generic Name: Levofloxacin + Azithromycin
  • Manufacturer: Indoco Remedies Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 atm lx 500 mg/500 mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा लेवोफ्लोक्सासिन 500 मिलीग्राम और एज़िथ्रोमाइसिन 500 मिलीग्राम का संयोजन है। यह गंभीर बैक्टीरियल संक्रमणों जैसे निमोनिया, त्वचा संक्रमण और श्वसन संक्रमण के इलाज के लिए डॉक्टर की देखरेख में दी जाती है। यह वायरल संक्रमण जैसे सर्दी-जुकाम के लिए नहीं है।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, दस्त, पेट दर्द, सिरदर्द, चक्कर आना और स्वाद में बदलाव शामिल हैं। गंभीर दुष्प्रभावों में टेंडन टूटना, तंत्रिका समस्याएं, लीवर की क्षति और हृदय की धड़कन में बदलाव शामिल हैं। कोई भी असामान्य लक्षण होने पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। पूरा कोर्स पूरा करें। शराब न लें। पर्याप्त पानी पिएं। एंटासिड, आयरन, जिंक या सुक्राल्फेट के साथ 2 घंटे का अंतर रखें। धूप से बचें। चक्कर आने पर वाहन न चलाएं। टेंडन में दर्द होने पर तुरंत डॉक्टर से मिलें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 atm lx 500 mg/500 mg tablet Uses & Benefits

[{"condition":"Community-acquired pneumonia","description":"Used when a clinician decides dual antibiotic coverage is needed for severe or complicated pneumonia.","evidence":"Well-established for the individual components; combination use is based on clinical judgment."},{"condition":"Complicated skin and soft tissue infections","description":"May be used when broad coverage against multiple bacteria is required.","evidence":"Limited for the fixed-dose combination; individual agents are established."},{"condition":"Mixed respiratory tract infections","description":"Sometimes prescribed when both typical and atypical bacteria are suspected.","evidence":"Limited for the combination; based on clinician experience."}]

Off-label uses: [{"condition":"Mycobacterial infections","description":"Azithromycin and levofloxacin are sometimes used in combination regimens for certain mycobacterial infections under specialist care.","evidence":"Limited and specialist-directed."}]

Primary treatment for: Bacterial infections

Also treats: Community-acquired pneumonia, Complicated skin infections, Mixed respiratory infections

📋 Drug Information

Generic Name(s)Levofloxacin + Azithromycin
Brand NameAzibact L 500 mg/500 mg Tablet
ManufacturerIndoco Remedies Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassFluoroquinolone + Macrolide Antibiotic
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Stay well hydrated throughout the day.
3
Avoid alcohol while taking this medicine.
4
Do not take antacids, iron, or zinc within 2 hours of this medicine.
5
Complete the full course even if you feel better.
6
Report any tendon pain, numbness, or vision changes immediately.
7
Avoid excessive sun exposure and use sunscreen.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Fever with productive cough
This medicine may be prescribed for bacterial pneumonia.
Likely Use
❌
Common cold
This medicine is not effective against viral infections.
Not Primary
✅
Skin infection with pus
May be used for complicated skin infections.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionLevofloxacin is rapidly and almost completely absorbed after oral administration. Azithromycin is also well absorbed orally, though food may slightly alter absorption. Specific values for this fixed-dose combination are not established from the available information.
DistributionBoth drugs distribute widely into body tissues and fluids. Levofloxacin penetrates lung tissue and macrophages. Azithromycin concentrates in phagocytes and is delivered to infection sites. Specific volume of distribution for the combination is not established from the available information.
Protein BindingLevofloxacin is approximately 24-38% protein bound. Azithromycin is approximately 7-50% protein bound depending on concentration. Values for the combination are not established from the available information.
MetabolismLevofloxacin undergoes minimal metabolism. Azithromycin is metabolized in the liver, primarily by CYP3A4, to inactive metabolites. Specific data for the combination are not established from the available information.
Half-LifeLevofloxacin half-life is about 6-8 hours. Azithromycin half-life is about 68 hours due to tissue accumulation. The combination half-life is not established from the available information.
ExcretionLevofloxacin is mainly excreted unchanged in urine. Azithromycin is excreted primarily in bile and feces, with a small amount in urine. Specific data for the combination are not established from the available information.
BioavailabilityLevofloxacin oral bioavailability is approximately 99%. Azithromycin oral bioavailability is approximately 37%. The bioavailability of this fixed-dose combination is not established from the available information.
Onset of ActionAntibacterial effects begin within hours of the first dose, but clinical improvement may take 24-72 hours. Specific onset for the combination is not established from the available information.
Peak Plasma TimeLevofloxacin peak plasma time is 1-2 hours. Azithromycin peak plasma time is 2-3 hours. The combination peak time is not established from the available information.
Duration of ActionLevofloxacin duration is about 24 hours per dose. Azithromycin has a long tissue half-life allowing once-daily dosing. The combination duration is not established from the available information.

How It Works

Levofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication and repair. Azithromycin binds to the 50S ribosomal subunit and inhibits protein synthesis. The two mechanisms are complementary and can be bactericidal or bacteriostatic depending on the organism and concentration.

Mechanism Steps

1
Levofloxacin enters bacteria: Levofloxacin penetrates the bacterial cell wall and reaches the cytoplasm.
2
DNA gyrase and topoisomerase IV inhibition: Levofloxacin binds these enzymes and blocks DNA replication, leading to bacterial cell death.
3
Azithromycin binds ribosome: Azithromycin attaches to the 50S ribosomal subunit and prevents peptide bond formation.
4
Protein synthesis stops: Without new proteins, bacteria cannot grow or divide, and are cleared by the immune system.

💡 How to Take atm lx 500 mg/500 mg tablet

Strength: Tablet containing Levofloxacin 500 mg and Azithromycin 500 mg.

1Take the tablet by mouth with a full glass of water.
2You may take it with or without food, but taking it with food may reduce stomach upset.
3Do not crush, chew, or break the tablet unless your doctor advises.
4Take at the same time each day to maintain consistent levels.
5Separate antacids, iron, zinc, or sucralfate by at least 2 hours.
6Complete the full course even if you feel better.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally once daily or as prescribed by your doctor. The exact dose and duration depend on the type and severity of infection, your kidney and liver function, and other medical conditions. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-medicate.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to side effects, especially tendon rupture, kidney effects, and heart rhythm changes. Dose adjustment may be needed based on kidney function. Consult your doctor.
Renal ImpairmentLevofloxacin requires dose adjustment in patients with reduced kidney function. Azithromycin generally does not require adjustment. Consult your doctor for personalized dosing.
Hepatic ImpairmentAzithromycin may require caution in severe liver impairment. Levofloxacin does not require adjustment in mild to moderate liver impairment. Consult your doctor.
Maximum Daily DoseThe maximum recommended daily dose is one tablet (Levofloxacin 500 mg + Azithromycin 500 mg) unless otherwise directed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Dairy products
Separate by 2 hours
Calcium reduces absorption of levofloxacin.
Antacids
Separate by 2 hours
Aluminum and magnesium reduce absorption.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of atm lx 500 mg/500 mg tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food and stay hydrated. Consult doctor if persistent.
Diarrhea (Common (5-10%))
Drink fluids. If severe or bloody, contact doctor immediately.
Headache (Common (5-10%))
Rest and hydrate. Consult doctor if severe or persistent.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you.
Altered taste (Common (5-10%))
Usually temporary. Consult doctor if bothersome.

🚨 Serious Side Effects

Tendon rupture or tendinitis (Rare (<0.1%))
Stop medicine and seek immediate medical attention if you have tendon pain, swelling, or difficulty moving a joint.
Peripheral neuropathy (Rare (<0.1%))
Report numbness, tingling, or burning in hands or feet to your doctor promptly.
Clostridioides difficile-associated diarrhea (Rare (<0.1%))
Seek medical attention if you have severe, persistent, or bloody diarrhea.
Liver injury (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe abdominal pain immediately.
QT prolongation and arrhythmias (Rare (<0.1%))
Seek emergency care if you experience palpitations, fainting, or seizures.

⚠️ Rare Side Effects

Severe allergic reactions (anaphylaxis)
Seek emergency care for swelling of face, lips, throat, or difficulty breathing.
Blood cell abnormalities
Report unusual bruising, bleeding, or signs of infection to your doctor.
Vision changes
Consult an eye specialist if you notice blurred vision or eye pain.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Amiodarone Major
Antacids Major
Corticosteroids Moderate
NSAIDs Moderate
Insulin Moderate
Theophylline Minor
Caffeine Minor

🚨 Major Interactions

  • QT-prolonging drugs (e.g., amiodarone, sotalol, quinidine)
  • Warfarin
  • Antacids, iron, zinc, sucralfate

⚡ Moderate Interactions

  • Corticosteroids
  • NSAIDs
  • Diabetes medicines (sulfonylureas, insulin)

🍷 Alcohol Interaction

Alcohol may increase the risk of dizziness, drowsiness, and liver effects. It is best to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to levofloxacin, azithromycin, or other quinolones or macrolides","History of tendon disorders with fluoroquinolones","Myasthenia gravis","Severe liver impairment","Concurrent use with QT-prolonging drugs unless clearly necessary"]

⚠️ Warnings & Precautions

["May cause tendon rupture, especially in elderly and corticosteroid users.","May cause peripheral neuropathy.","May worsen muscle weakness in myasthenia gravis.","May cause central nervous system effects including seizures.","May cause severe diarrhea due to C. difficile.","May cause blood sugar disturbances in diabetics.","Avoid excessive sun exposure due to photosensitivity risk.","Use with caution in patients with kidney or liver disease.","Do not use for viral infections.","Complete the full course as prescribed."]

🤱 Lactation Safety

Both levofloxacin and azithromycin are excreted in breast milk. Consult your doctor before breastfeeding while taking this medicine.

💊 Overdose Management

Seek emergency medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Monitor ECG and electrolytes.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not share it with others. Complete the full course even if you feel better. Avoid alcohol while taking this medicine. Stay well hydrated. Do not take antacids, iron, zinc, or sucralfate within 2 hours before or after this medicine. Avoid excessive sunlight and use sunscreen. Tell your doctor about all other medicines you take, especially blood thinners, diabetes medicines, and heart rhythm medicines. Do not drive or operate machinery if you feel dizzy. If you develop tendon pain, stop and call your doctor immediately. If you have diarrhea that is severe or bloody, contact your doctor before taking anti-diarrheal medicines.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of tendon rupture, kidney problems, and heart rhythm changes. Dose adjustment may be needed based on kidney function. Close monitoring is advised.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before taking this medicine. Both levofloxacin and azithromycin should be used during pregnancy only if clearly needed.

🏥 Post-Surgery Considerations

Inform your surgeon if you are taking this medicine before any surgery. It may interact with anesthetics and other medications.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine. It may interact with certain antibiotics or painkillers used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce stress on joints.
🥗
Regular low-impact exercise like walking or swimming.
😴
Practice good posture.
💧
Include anti-inflammatory foods in your diet.
🧘
Get adequate sleep to support immune function.
🌞
Stay well hydrated.

🏋️ Exercise Considerations

Avoid strenuous exercise or heavy lifting while taking this medicine, as it may increase the risk of tendon injury. Consult your doctor before starting any new exercise routine.

🥗 Diet Recommendations

Include omega-3 rich foods
Reduce processed food intake
Stay well hydrated
Avoid alcohol
Limit caffeine

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness. Avoid driving or operating heavy machinery until you know how it affects you. Take rest as needed.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience serious side effects like tendon pain, severe diarrhea, or allergic reactions, stop immediately and seek medical help.

📅 Long-Term Use Effects

Long-term use of this medicine can increase the risk of antibiotic resistance, tendon problems, nerve damage, and liver or kidney issues. It should only be used for the prescribed duration. Regular monitoring may be needed if used for prolonged periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Targeted antibiotic therapy

Based on culture and sensitivity, a narrower antibiotic may be used.

Evidence: Well-established
Supportive care

Rest, fluids, and fever control can complement antibiotic therapy.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Antibiotics do not interfere with most vaccines. However, consult your doctor about timing if you are scheduled for any vaccine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing times gradually as advised by your doctor. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with community-acquired pneumonia
He was prescribed this medicine by his doctor for severe pneumonia. He took it with food as advised and completed the 7-day course. His fever subsided in 3 days and he recovered fully. He was advised to avoid alcohol and antacids during treatment.
💡 Lesson: Taking the medicine with food and completing the full course led to a successful recovery.
👤 A 40-year-old woman with a complicated skin infection
She developed a severe skin infection after a minor injury. Her doctor prescribed this combination. She experienced mild nausea but managed it by taking the tablet with meals. The infection cleared within 10 days.
💡 Lesson: Mild side effects can be managed with food, and completing the course prevents recurrence.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 24-72 hours, but you must complete the full course as prescribed.

Q: Can I take it with food?

A: Yes, taking it with food can reduce stomach upset. However, avoid dairy and antacids within 2 hours of the dose.

Q: What if I miss a dose?

A: Take it as soon as you remember. If it is almost time for the next dose, skip the missed dose. Do not double dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for atm lx 500 mg/500 mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure any infection.
    Fact: It only works for specific bacterial infections and should not be used for viral infections.
  • Myth: You can stop taking it once you feel better.
    Fact: You must complete the full course to prevent resistance and relapse.
  • Myth: It is safe to take with any other medicine.
    Fact: It can interact with many medicines, so always inform your doctor.

🔄 Alternative Options

Generic Alternatives

  • Levofloxacin 500 mg + Azithromycin 500 mg tablet (generic)

Brand Alternatives

  • Azibact L 500 mg/500 mg tablet

📊 Comparison with Similar Medicines

[{"medicine":"Levofloxacin alone","difference":"Single antibiotic, narrower coverage."},{"medicine":"Azithromycin alone","difference":"Single antibiotic, different spectrum."},{"medicine":"This combination","difference":"Dual coverage, used for serious infections."}]

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