atenom 1000mg injection - Uses, Price, Side Effects & Substitutes
What is atenom 1000mg injection used for?
Azenam 1gm Injection (Aztreonam) is used to treat ANTI INFECTIVES. It contains Aztreonam (1000mg), which Inhibits bacterial cell wall synthesis by binding to penicillin-binding protein . Always consult your doctor before use. Take as prescribed.
- Generic Name: Aztreonam
- Manufacturer: Mandevis Pharma
- Form: Allopathy
- Pregnancy Category: B
- Prescription Required: Yes
๐ atenom 1000mg injection Uses & Benefits
Treatment of infections caused by susceptible Gram-negative bacteria including urinary tract infections, lower respiratory tract infections, septicemia, skin and skin structure infections, intra-abdominal infections, and gynecologic infections.
Off-label uses: Febrile neutropenia (in combination), Meningitis (with inflamed meninges)
๐ Drug Information
| Generic Name(s) | Aztreonam |
| Brand Name | Azenam 1gm Injection |
| Manufacturer | Mandevis Pharma |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Monobactams |
| Route of Administration | Intravenous (IV) or intramuscular (IM) injection. |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light; reconstituted solutions stable for 48 hours at room temperature or 7 days under refrigeration. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits bacterial cell wall synthesis by binding to penicillin-binding protein 3 (PBP3), leading to cell lysis and death.
Mechanism Steps
๐ก How to Take atenom 1000mg injection
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of atenom 1000mg injection
โ Common Side Effects
- Injection site reactions (pain, phlebitis)
- Diarrhea
- Nausea
- Vomiting
- Rash
๐จ Serious Side Effects
- Severe hypersensitivity reactions (anaphylaxis)
- Clostridioides difficile-associated diarrhea
- Seizures
- Hepatotoxicity
โ ๏ธ Rare Side Effects
- Pseudomembranous colitis
- Blood dyscrasias (neutropenia, thrombocytopenia)
- Interstitial nephritis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Live Typhoid Vaccine | Major | Reduced vaccine efficacy |
| BCG Vaccine | Major | Reduced vaccine efficacy |
| Probenecid | Moderate | Decreased renal excretion of aztreonam |
| Aminoglycosides | Moderate | Increased nephrotoxicity risk |
| Furosemide | Moderate | Increased nephrotoxicity risk |
| Chloramphenicol | Minor | Antagonistic effect |
| Tetracyclines | Minor | Antagonistic effect |
๐จ Major Interactions
- Warfarin
- Live Typhoid Vaccine
- BCG Vaccine
โก Moderate Interactions
- Probenecid
- Aminoglycosides
- Furosemide
โน๏ธ Minor Interactions
- Chloramphenicol
- Tetracyclines
๐ฝ๏ธ Food Interactions
No significant food interactions; injection only.
๐ท Alcohol Interaction
No known interaction.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to aztreonam or any component of the formulation.
๐ Monitoring Parameters
Renal function (especially in elderly or with concurrent nephrotoxic drugs), liver function tests, signs of hypersensitivity, and superinfection.
๐คฑ Lactation Safety
Excreted in breast milk in low concentrations; generally considered compatible with breastfeeding.
๐ Overdose Management
Supportive care; hemodialysis may enhance elimination.
โฐ Missed Dose
Administer as soon as possible; if near next dose, skip missed dose and resume regular schedule.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for atenom 1000mg injection
View AllAlternative brands with exact same active ingredient (Aztreonam (1000mg)):
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azy 1000mg injectionMedilife Health Sciences Pvt Ltd โน571.88 4.8% COSTLIER
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azvzn 1000mg injectionAlwin Wilcare Pharmaceuticals โน595.00 9.1% COSTLIER
Medical Note: Always consult your doctor before switching medications.