atelol d 50mg/2.5mg tablet - Atenolol (50mg) + Indapamide (2.5mg) medicine

Atelol D 50mg/2.5mg Tablet: Complete Information

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🏭 Themis Pharmaceuticals Prop Chemosyn Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Nov 1, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for hypertension.
Reviewed by
SaathiMed Expert Panel | Nov 01, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe dizziness or fainting
  • Heart rate below 50 beats per minute
  • Difficulty breathing or wheezing
  • Swelling of face, lips, or throat
  • Chest pain or irregular heartbeat
  • Severe muscle cramps or weakness
  • Decreased urine output
  • Yellowing of skin or eyes

If experiencing severe symptoms, call emergency services immediately.

What is atelol d 50mg/2.5mg tablet used for?

This medicine is a combination of Atenolol (a beta-blocker) and Indapamide (a diuretic) used to treat high blood pressure. It works by slowing the heart rate and removing excess fluid from the body.

  • Generic Name: Atenolol (50mg) + Indapamide (2.5mg)
  • Manufacturer: Themis Pharmaceuticals Prop Chemosyn Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 atelol d 50mg/2.5mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा उच्च रक्तचाप (हाइपरटेंशन) के इलाज के लिए इस्तेमाल की जाती है। यह एटेनोलोल और इंडापामाइड का संयोजन है, जो रक्तचाप को कम करने में मदद करता है। यह दिल पर दबाव कम करती है और शरीर से अतिरिक्त पानी और नमक को बाहर निकालती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में थकान, चक्कर आना, ठंडे हाथ-पैर, धीमी हृदय गति, सिरदर्द और बार-बार पेशाब आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इसमें गंभीर धीमी हृदय गति, हृदय रुकावट, एलर्जी प्रतिक्रिया और इलेक्ट्रोलाइट असंतुलन शामिल हो सकते हैं।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। अचानक बंद न करें। शराब से बचें। पर्याप्त पानी पिएं। नियमित रूप से रक्तचाप, हृदय गति और रक्त परीक्षण कराएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 atelol d 50mg/2.5mg tablet Uses & Benefits

[{"condition":"Hypertension","description":"This medicine is used to lower high blood pressure in adults when a combination of a beta-blocker and a diuretic is appropriate.","evidence":"Well-established"},{"condition":"Angina pectoris","description":"Atenolol component helps reduce the frequency and severity of angina attacks by decreasing heart workload.","evidence":"Well-established"},{"condition":"Edema","description":"Indapamide component helps reduce fluid retention in conditions such as heart failure or renal impairment.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Migraine prophylaxis","description":"Beta-blockers like Atenolol are sometimes used off-label to prevent migraines, but this combination is not specifically approved for that purpose.","evidence":"Limited"},{"condition":"Anxiety with palpitations","description":"Atenolol may be used off-label to manage physical symptoms of anxiety such as rapid heartbeat, but this is not a standard use of the combination.","evidence":"Limited"}]

Primary treatment for: Hypertension

Also treats: Angina pectoris, Edema

📋 Drug Information

Generic Name(s)Atenolol (50mg) + Indapamide (2.5mg)
Brand Nameatelol d 50mg/2.5mg tablet
ManufacturerThemis Pharmaceuticals Prop Chemosyn Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action Class
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day, preferably in the morning, to establish a routine.
2
Monitor your blood pressure regularly and keep a record to share with your doctor.
3
Do not stop this medicine abruptly; always consult your doctor before making any changes.
4
Stay hydrated, especially during hot weather or exercise, to prevent dehydration.
5
Avoid alcohol as it can increase dizziness and low blood pressure.
6
Report any unusual symptoms like severe dizziness, fainting, or muscle cramps to your doctor immediately.
7
If you have diabetes, monitor your blood sugar closely as this medicine may mask hypoglycemia symptoms.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
High blood pressure
This medicine is commonly prescribed for this.
Likely Use
✅
Angina
Atenolol component helps reduce angina.
Likely Use
✅
Fluid retention
Indapamide component helps reduce edema.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAtenolol is rapidly but incompletely absorbed from the gastrointestinal tract, with an oral bioavailability of approximately 50%. Indapamide is rapidly and completely absorbed from the gastrointestinal tract, with a bioavailability of about 93%.
DistributionAtenolol is widely distributed in body tissues, with low protein binding (approximately 3%). Indapamide is highly bound to plasma proteins and also distributes into body tissues.
Protein BindingAtenolol: approximately 3%; Indapamide: approximately 71-79%.
MetabolismAtenolol is minimally metabolized in the liver. Indapamide is extensively metabolized in the liver, primarily by CYP3A4.
Half-LifeAtenolol: 6-7 hours; Indapamide: approximately 14-18 hours.
ExcretionAtenolol is primarily excreted unchanged in the urine. Indapamide is excreted in urine (70%) and feces (23%) as unchanged drug and metabolites.
BioavailabilityAtenolol: ~50%; Indapamide: ~93%.
Onset of ActionAtenolol: within 1 hour; Indapamide: within 1-2 hours.
Peak Plasma TimeAtenolol: 2-4 hours; Indapamide: 1-2 hours.
Duration of ActionAtenolol: 24 hours; Indapamide: 24-36 hours.

How It Works

This medicine combines two active ingredients with complementary mechanisms. Atenolol selectively blocks beta-1 adrenergic receptors in the heart, reducing heart rate, contractility, and cardiac output, which lowers blood pressure and myocardial oxygen demand. Indapamide inhibits sodium reabsorption in the distal convoluted tubule of the kidney, increasing excretion of sodium, chloride, and water, which reduces plasma volume and peripheral vascular resistance. The combined effect provides effective blood pressure reduction.

Mechanism Steps

1
Beta-1 receptor blockade: Atenolol binds to beta-1 adrenergic receptors in the heart, blocking the effects of catecholamines like adrenaline.
2
Reduced cardiac output: This blockade leads to a slower heart rate and reduced force of contraction, decreasing cardiac output.
3
Diuretic action: Indapamide inhibits sodium reabsorption in the distal tubule, promoting excretion of sodium and water.
4
Reduced plasma volume: The increased diuresis reduces plasma volume, which lowers blood pressure.
5
Combined antihypertensive effect: The combined actions of reduced cardiac output and reduced plasma volume result in effective blood pressure control.

💡 How to Take atelol d 50mg/2.5mg tablet

Strength: Tablet containing Atenolol 50 mg and Indapamide 2.5 mg.

1Take the tablet orally with a glass of water.
2Swallow it whole; do not crush or chew.
3Take it at the same time each day, preferably in the morning.
4You may take it with or without food, but with food if it upsets your stomach.
5Do not stop taking this medicine without consulting your doctor.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally once daily, preferably in the morning. The dose may be adjusted by your doctor based on your blood pressure response and tolerance. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, especially dizziness and electrolyte imbalances. Start with a lower dose and monitor closely. Dose must be individualized by a qualified clinician.
Renal ImpairmentIn patients with renal impairment, dose adjustment is required. Atenolol is renally excreted; reduce dose if creatinine clearance is below 35 mL/min. Indapamide should be used with caution. Consult your doctor for specific dosing.
Hepatic ImpairmentIn patients with hepatic impairment, Indapamide metabolism may be affected. Use with caution and monitor liver function. Dose adjustment may be necessary. Consult your doctor.
Maximum Daily DoseOne tablet daily (Atenolol 50 mg + Indapamide 2.5 mg). Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
May enhance blood pressure lowering and cause dizziness.
High-potassium foods
Monitor intake
Indapamide can cause potassium loss; consult doctor about dietary needs.

⏰ What to Do If You Miss a Dose

📌 Less than 12 hours have passed since the missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 12 hours have passed since the missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of atelol d 50mg/2.5mg tablet

✅ Common Side Effects

Fatigue (Common (5-10%))
Usually resolves with continued use. Consult doctor if persistent.
Dizziness (Common (5-10%))
Rise slowly from sitting or lying position. Avoid driving if affected.
Cold extremities (Common (5-10%))
Keep hands and feet warm. Report if severe or persistent.
Increased urination (Common (5-10%))
Take dose earlier in the day to avoid nighttime urination.
Headache (Common (5-10%))
Usually resolves. Use acetaminophen if needed, but consult doctor.

🚨 Serious Side Effects

Severe bradycardia (Rare (<0.1%))
Seek immediate medical attention if heart rate drops below 50 beats per minute or you feel faint.
Heart block (Rare (<0.1%))
Report symptoms like dizziness, fainting, or irregular heartbeat to your doctor immediately.
Severe allergic reaction (Rare (<0.1%))
Seek emergency care if you experience rash, swelling of face/lips/throat, or difficulty breathing.
Electrolyte imbalance (Uncommon (0.1-1%))
Report muscle cramps, weakness, confusion, or irregular heartbeat to your doctor.

⚠️ Rare Side Effects

Bronchospasm
Seek medical attention if you experience wheezing or difficulty breathing.
Severe skin reactions
Discontinue and seek immediate care if you develop blistering rash or peeling skin.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Verapamil Major
Clonidine Major
Lithium Major
NSAIDs Moderate
Corticosteroids Moderate
Antidiabetic drugs Moderate
Digoxin Minor
Antacids Minor

🚨 Major Interactions

  • Verapamil or Diltiazem
  • Clonidine
  • Lithium

⚡ Moderate Interactions

  • NSAIDs
  • Corticosteroids
  • Antidiabetic drugs

🍷 Alcohol Interaction

Alcohol may enhance the blood pressure-lowering effects of this medicine and increase the risk of dizziness, fainting, and orthostatic hypotension. It is advisable to avoid or limit alcohol consumption while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Severe bradycardia","Second or third-degree heart block","Cardiogenic shock","Decompensated heart failure","Severe renal impairment (creatinine clearance

⚠️ Warnings & Precautions

["Do not stop abruptly; taper gradually to avoid rebound angina or hypertension.","Use with caution in patients with asthma or COPD; may cause bronchospasm.","May mask symptoms of hypoglycemia in diabetic patients.","Can cause electrolyte imbalances; monitor potassium and sodium levels.","May worsen peripheral vascular disease.","Use with caution in elderly patients; increased risk of falls and electrolyte disturbances.","Avoid in pregnancy unless clearly needed; may cause fetal harm.","Not recommended during breastfeeding."]

🤱 Lactation Safety

Atenolol is excreted in breast milk and may cause bradycardia and hypotension in the nursing infant. Indapamide is also excreted in breast milk. This medicine is not recommended during breastfeeding unless the potential benefit outweighs the risk. Consult your doctor.

💊 Overdose Management

Overdose may cause severe bradycardia, hypotension, heart failure, and electrolyte disturbances. Treatment is supportive and symptomatic. Gastric lavage may be considered if recent ingestion. Administer intravenous fluids, atropine for bradycardia, and vasopressors for hypotension. Monitor electrolytes and renal function. Contact a poison control center immediately.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not stop taking it suddenly, as abrupt withdrawal of Atenolol can worsen angina or lead to a heart attack. Inform your doctor if you have asthma, diabetes, kidney or liver disease, or thyroid disorders. Avoid alcohol as it can enhance the blood pressure-lowering effect and cause dizziness. Stay hydrated, especially during hot weather or exercise, to prevent dehydration and electrolyte imbalance. Regular monitoring of blood pressure, heart rate, and blood tests for kidney function and electrolytes is important. Do not use potassium supplements without medical advice. If you are scheduled for surgery, inform your surgeon and anesthesiologist about this medicine.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to dizziness, electrolyte imbalances, and falls. Start with a lower dose and monitor closely. Regular blood tests are essential.

🤰 Pregnancy Planning (TTC)

This medicine is not recommended during pregnancy as it may harm the fetus. If you are planning pregnancy, consult your doctor to switch to a safer alternative. Use effective contraception while on this medicine.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist about this medicine. It may interact with anesthesia and affect heart rate and blood pressure. Your doctor may adjust or temporarily stop it before surgery.

🦷 Dental Procedures

Inform your dentist about this medicine. It may cause dry mouth or interact with local anesthetics containing epinephrine. Monitor blood pressure during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce blood pressure.
🥗
Engage in regular moderate exercise like walking or swimming.
😴
Limit salt intake to help control blood pressure.
💧
Avoid smoking and limit alcohol consumption.
🧘
Manage stress through relaxation techniques like yoga or meditation.
🌞
Get adequate sleep to support heart health.

🏋️ Exercise Considerations

Moderate exercise is generally safe, but avoid strenuous activities initially as this medicine may cause dizziness or fatigue. Stay hydrated and monitor your heart rate. Consult your doctor before starting a new exercise program.

🥗 Diet Recommendations

Reduce sodium intake
Increase potassium-rich foods like bananas and oranges (if approved by doctor)
Limit processed foods
Stay well hydrated
Include fiber-rich foods

💼 Impact on Daily Work & Life

This medicine may cause dizziness or fatigue, especially when starting treatment. Avoid driving or operating heavy machinery until you know how it affects you. Take it in the morning to minimize nighttime urination. Adjust work schedules if needed.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. Abrupt withdrawal can cause rebound hypertension, angina, or heart attack. Your doctor may taper the dose gradually if needed.

📅 Long-Term Use Effects

Long-term use may require regular monitoring of blood pressure, heart rate, kidney function, and electrolytes. Atenolol can cause fatigue and cold extremities. Indapamide can lead to electrolyte imbalances. Periodic blood tests are essential. Do not stop without medical advice.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet, exercise, and stress reduction can help manage blood pressure.

Evidence: Well-established
Other antihypertensive classes

ACE inhibitors, ARBs, or calcium channel blockers may be alternatives.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. However, inform your doctor about this medicine before any vaccination. Continue routine vaccinations as recommended.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage. Adjust dosing times if crossing time zones, but consult your doctor first. Store at room temperature and protect from extreme heat or moisture. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with a history of hypertension and angina
He was prescribed this medicine after his blood pressure remained high on a single drug. Within a few weeks, his blood pressure stabilized, and he experienced fewer angina attacks. He initially felt tired but adjusted after a month. He emphasizes taking it regularly and monitoring his heart rate.
💡 Lesson: Combination therapy can be effective when single drugs fail, but regular monitoring and patience are key.
👤 A 62-year-old woman with hypertension and mild heart failure
She started this medicine and noticed increased urination, which was managed by taking it in the morning. Her blood pressure improved, but she developed low potassium, which was corrected with diet and supplements. She advises regular blood tests.
💡 Lesson: Electrolyte monitoring is crucial, and simple adjustments like timing can improve tolerability.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts lowering blood pressure within a few hours, but full effects may take 1-2 weeks. Regular monitoring is important.

Q: Can I stop taking this medicine if I feel better?

A: No, do not stop without consulting your doctor. High blood pressure often has no symptoms, and stopping suddenly can be dangerous.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember if less than 12 hours have passed. If more than 12 hours, skip it and continue your regular schedule. Do not double dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my diabetes medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for atelol d 50mg/2.5mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be stopped once blood pressure is normal.
    Fact: High blood pressure often requires lifelong treatment. Stopping suddenly can cause rebound hypertension or angina.
  • Myth: This medicine causes kidney damage.
    Fact: When used as prescribed and monitored, this medicine is safe. Regular monitoring helps prevent kidney issues.
  • Myth: You can take this medicine without a prescription.
    Fact: This is a prescription medicine. It should only be taken under a doctor's supervision.

🔄 Alternative Options

Generic Alternatives

  • Atenolol + Indapamide generic tablets

Brand Alternatives

  • Atelol D 50mg/2.5mg tablet

📊 Comparison with Similar Medicines

[{"medicine":"Atelol D","composition":"Atenolol 50mg + Indapamide 2.5mg","class":"Beta-blocker + Diuretic","primary_use":"Hypertension"},{"medicine":"Atenolol + Chlorthalidone","composition":"Atenolol 50mg + Chlorthalidone 12.5mg","class":"Beta-blocker + Diuretic","primary_use":"Hypertension"}]

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