asrapime 1000mg injection - Cefepime (1000mg) medicine

asrapime 1000mg injection - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Asrawell Lifecare ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 27, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 27, 2026

What is asrapime 1000mg injection used for?

Appime 250mg Injection (Cefepime) is used to treat ANTI INFECTIVES. It contains Cefepime (1000mg), which Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Cefepime
  • Manufacturer: Asrawell Lifecare
  • Form: Allopathy
  • Pregnancy Category: B
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š asrapime 1000mg injection Uses & Benefits

Treatment of pneumonia, urinary tract infections, skin and soft tissue infections, intra-abdominal infections, febrile neutropenia.

Off-label uses: Meningitis, Osteomyelitis

๐Ÿ“‹ Drug Information

Generic Name(s)Cefepime
Brand NameAppime 250mg Injection
ManufacturerAsrawell Lifecare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassCephalosporins: 4th generation
Route of AdministrationIntravenous (IV) or intramuscular (IM)
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionIntravenous administration results in complete bioavailability.
DistributionWidely distributed into tissues and body fluids including cerebrospinal fluid.
Protein BindingApproximately 20%
MetabolismPartially metabolized to N-methylpyrrolidine (NMP) which is rapidly converted to N-methylpyrrolidine oxide.
Half-LifeApproximately 2 hours
ExcretionPrimarily excreted unchanged in urine via glomerular filtration and tubular secretion.
Bioavailability100% (intravenous)
Onset of ActionRapid
Peak Plasma TimeEnd of infusion
Duration of ActionApproximately 12 hours

How It Works

Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to cell lysis.

Mechanism Steps

1Cefepime binds to penicillin-binding proteins (PBPs) located on the bacterial cell wall.
2Inhibition of transpeptidase enzymes prevents cross-linking of peptidoglycan chains.
3Autolytic enzymes are activated, leading to cell wall degradation and bacterial lysis.

๐Ÿ’ก How to Take asrapime 1000mg injection

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of asrapime 1000mg injection

โœ… Common Side Effects

  • Diarrhea
  • Nausea
  • Vomiting
  • Rash
  • Injection site reactions

๐Ÿšจ Serious Side Effects

  • Anaphylaxis
  • Clostridioides difficile colitis
  • Seizures
  • Acute renal failure

โš ๏ธ Rare Side Effects

  • Hemolytic anemia
  • Agranulocytosis
  • Stevens-Johnson syndrome

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Aminoglycosides Major Increased risk of nephrotoxicity and ototoxicity
Loop diuretics Major Increased risk of nephrotoxicity
Probenecid Major Decreased renal excretion of cefepime, increased plasma levels
Warfarin Moderate Possible increased INR
Oral contraceptives Moderate Reduced efficacy of contraceptives
Antacids Minor No significant interaction

๐Ÿšจ Major Interactions

  • Aminoglycosides
  • Loop diuretics
  • Probenecid

โšก Moderate Interactions

  • Warfarin
  • Oral contraceptives

โ„น๏ธ Minor Interactions

  • Antacids

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

No known interaction.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to cefepime or other cephalosporins, penicillins, or beta-lactam antibiotics.

๐Ÿ“Š Monitoring Parameters

Renal function, complete blood count, signs of hypersensitivity, superinfection.

๐Ÿคฑ Lactation Safety

Excreted in breast milk in low concentrations; use with caution.

๐Ÿ’Š Overdose Management

Supportive care; hemodialysis may enhance elimination.

โฐ Missed Dose

Administer as soon as remembered; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 27, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for asrapime 1000mg injection

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Alternative brands with exact same active ingredient (Cefepime (1000mg)):

Medical Note: Always consult your doctor before switching medications.

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