as-xime-o tablet - Uses, Price, Side Effects & Substitutes
What is as-xime-o tablet used for?
Abixim O Tablet (Cefixime + Ofloxacin) is used to treat ANTI INFECTIVES. It contains Cefixime (200mg) + Ofloxacin (200mg), which Cefixime inhibits bacterial cell wall synthesis; Ofloxacin inhibits DNA gyrase a. Always consult your doctor before use. Take as prescribed.
- Generic Name: Cefixime + Ofloxacin
- Manufacturer: Asvins Lifecare
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ as-xime-o tablet Uses & Benefits
Respiratory tract infections, urinary tract infections, gastrointestinal infections, skin and soft tissue infections, sexually transmitted infections
Off-label uses: Typhoid fever, Leprosy, Brucellosis
๐ Drug Information
| Generic Name(s) | Cefixime + Ofloxacin |
| Brand Name | Abixim O Tablet |
| Manufacturer | Asvins Lifecare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Antibiotic (Cephalosporin + Fluoroquinolone) |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC, protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Cefixime inhibits bacterial cell wall synthesis; Ofloxacin inhibits DNA gyrase and topoisomerase IV
Mechanism Steps
๐ก How to Take as-xime-o tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of as-xime-o tablet
โ Common Side Effects
- Nausea
- Diarrhea
- Headache
- Dizziness
- Abdominal pain
- Vomiting
- Dyspepsia
๐จ Serious Side Effects
- Tendon rupture
- Peripheral neuropathy
- Severe allergic reactions
- Clostridium difficile colitis
- QT prolongation
- Seizures
- Hepatotoxicity
โ ๏ธ Rare Side Effects
- Blood dyscrasias
- Stevens-Johnson syndrome
- Toxic epidermal necrolysis
- Interstitial nephritis
- Anaphylaxis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Antidiabetic agents | Major | Hypoglycemia |
| NSAIDs | Major | Increased CNS stimulation and seizure risk |
| Theophylline | Major | Increased theophylline toxicity |
| Corticosteroids | Major | Increased risk of tendon rupture |
| Antacids | Moderate | Reduced absorption of ofloxacin |
| Iron supplements | Moderate | Reduced absorption of ofloxacin |
| Zinc supplements | Moderate | Reduced absorption of ofloxacin |
| Sucralfate | Moderate | Reduced absorption of ofloxacin |
| Probenecid | Moderate | Increased cefixime levels |
| Caffeine | Minor | Increased caffeine effects |
| Cyclosporine | Minor | Possible nephrotoxicity |
| Methotrexate | Minor | Increased methotrexate levels |
๐จ Major Interactions
- Warfarin
- Antidiabetic agents
- NSAIDs
- Theophylline
- Corticosteroids
โก Moderate Interactions
- Antacids
- Iron supplements
- Zinc supplements
- Sucralfate
- Probenecid
โน๏ธ Minor Interactions
- Caffeine
- Cyclosporine
- Methotrexate
๐ฝ๏ธ Food Interactions
Avoid dairy products, antacids, and iron supplements within 2-4 hours; food may delay absorption
๐ท Alcohol Interaction
Avoid alcohol; may increase CNS effects and hepatotoxicity risk
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to cephalosporins, fluoroquinolones, or any component; history of tendon disorders with fluoroquinolones; pregnancy (ofloxacin); children <18 years (ofloxacin)
๐ Monitoring Parameters
Renal function, hepatic function, blood glucose (in diabetics), signs of tendonitis, CNS effects, QT interval
๐คฑ Lactation Safety
Excreted in breast milk; use with caution
๐ Overdose Management
Supportive care; gastric lavage; monitor renal function and ECG
โฐ Missed Dose
Take as soon as remembered; skip if almost time for next dose; do not double dose