arobrim eye drop - Brimonidine (0.15% w/v) medicine

Arobrim Eye Drop (Brimonidine 0.15% w/v) - Uses, Price, Side Effects

4.5 (12 reviews)

Brimonidine (0.15% w/v)

🏭 Aromed Pharmaceuticals 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 23, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 23, 2026

What is arobrim eye drop used for?

Arobrim Eye Drop contains Brimonidine 0.15% w/v, an alpha-2 adrenergic agonist that reduces intraocular pressure by decreasing aqueous humor production and increasing uveoscleral outflow. It is used to treat open-angle glaucoma and ocular hypertension. Typically instilled twice daily, it helps prevent optic nerve damage and vision loss.

Generic Name: Brimonidine
Manufacturer: Aromed Pharmaceuticals
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 arobrim eye drop Uses & Benefits

Reduction of intraocular pressure in open-angle glaucoma or ocular hypertension.

Off-label uses: Rosacea (topical), reduction of ocular redness (over-the-counter formulations).

📋 Drug Information

Generic Name(s)	Brimonidine
Brand Name	Alcon Brimo Eye Drop
Manufacturer	Aromed Pharmaceuticals
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	OPHTHAL
Action Class	Sympathomimetics- Ocular
Route of Administration	Ophthalmic (topical to the eye).
Storage	Store at 15-25°C; protect from light; keep bottle tightly closed.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionMinimal systemic absorption after ocular administration; peak plasma concentration reached within 1-2 hours.

DistributionDistributes into ocular tissues; systemic distribution is limited due to low absorption.

Protein BindingApproximately 29% bound to plasma proteins.

MetabolismExtensively metabolized in the liver via aldehyde oxidase and cytochrome P450 enzymes.

Half-LifeApproximately 2-3 hours in plasma; ocular half-life is longer.

ExcretionPrimarily excreted in urine (74%) as metabolites; unchanged drug accounts for less than 5%.

BioavailabilityLow systemic bioavailability due to extensive first-pass metabolism and local administration.

Onset of ActionWithin 1-2 hours after instillation.

Peak Plasma Time1-2 hours after ocular administration.

Duration of ActionUp to 12 hours.

How It Works

Selective alpha-2 adrenergic receptor agonist that reduces aqueous humor production and increases uveoscleral outflow.

Mechanism Steps

1Brimonidine binds to alpha-2 adrenergic receptors on the ciliary epithelium and trabecular meshwork.

2Activation of Gi protein-coupled receptors inhibits adenylyl cyclase, reducing cAMP levels.

3Decreased cAMP leads to reduced aqueous humor production by the ciliary body.

💡 How to Take arobrim eye drop

Follow your doctor's prescription exactly.

Dosage Timeline

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ✅

⚠️ Side Effects of arobrim eye drop

✅ Common Side Effects

Ocular burning/stinging
Blurred vision
Dry mouth
Fatigue
Drowsiness

🚨 Serious Side Effects

Severe allergic reaction
Bradycardia
Hypotension
Apnea in infants

⚠️ Rare Side Effects

Uveitis
Iritis
Corneal edema
Depression

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Beta-blockers (e.g., Timolol)	Moderate	Additive lowering of intraocular pressure and potential cardiovascular effects
MAO inhibitors	Major	Risk of hypertensive crisis
Tricyclic antidepressants	Moderate	Reduced efficacy of brimonidine

🚨 Major Interactions

MAO inhibitors
Tricyclic antidepressants
Beta-blockers (systemic)

⚡ Moderate Interactions

Antihypertensives
Cardiac glycosides
CNS depressants

ℹ️ Minor Interactions

Topical beta-blockers
Carbonic anhydrase inhibitors

🍽️ Food Interactions

No significant food interactions.

🍷 Alcohol Interaction

May enhance CNS depressant effects; caution advised.

🛡️ Safety & Warnings

Liver

Low

Kidney

Low

Heart

Low

Pregnancy

Category A

🚫 Contraindications

Hypersensitivity to brimonidine or any component; patients receiving MAO inhibitors; neonates and infants (risk of apnea).

📊 Monitoring Parameters

Intraocular pressure; heart rate and blood pressure in at-risk patients; signs of ocular irritation or allergy.

🤱 Lactation Safety

Excreted in breast milk in small amounts; caution advised.

💊 Overdose Management

If accidental ingestion, induce emesis or gastric lavage; monitor for CNS depression, bradycardia, hypotension; supportive care.

⏰ Missed Dose

Instill as soon as remembered; if near next dose, skip missed dose and resume regular schedule; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 23, 2026

🔗 View Profile

🔄 Substitutes for arobrim eye drop

View All

Alternative brands with exact same active ingredient (Brimonidine (0.15% w/v)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Regular Customer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Trusted Reviewer Jul 10, 2026