analar eye drop - Naphazoline (0.05% w/v) + Chlorpheniramine Maleate (0.01% w/v) medicine

Analar Eye Drop: Comprehensive Guide to Uses, Side Effects, and Safety

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🏭 Pharmtak Ophtalmics India Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 22, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for symptomatic relief of allergic conjunctivitis.
Reviewed by
SaathiMed Expert Panel | Sep 22, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe eye pain or sudden vision loss
  • Swelling of face, lips, or throat
  • Difficulty breathing or swallowing
  • Persistent worsening redness or irritation
  • Fast or irregular heartbeat
  • Severe headache with nausea

If experiencing severe symptoms, call emergency services immediately.

What is analar eye drop used for?

This medicine is an eye drop combining naphazoline (a decongestant) and chlorpheniramine (an antihistamine) to quickly relieve redness, itching, and watering caused by eye allergies. It is for short-term use only.

  • Generic Name: Naphazoline + Chlorpheniramine Maleate
  • Manufacturer: Pharmtak Ophtalmics India Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 analar eye drop के बारे में (Hindi Summary)

उपयोग: यह दवा आंखों की एलर्जी, लालिमा, खुजली और पानी आने में राहत देती है। इसमें नैफाजोलिन और क्लोरफेनिरामिन मेलिएट होते हैं जो आंखों की रक्त वाहिकाओं को सिकोड़ते हैं और हिस्टामिन को रोकते हैं। यह केवल आंखों में डालने के लिए है और डॉक्टर की सलाह से ही इस्तेमाल करें।

साइड इफेक्ट्स: आम दुष्प्रभावों में आंखों में जलन, धुंधली दृष्टि, सिरदर्द और नींद आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन तेज दर्द, लालिमा बढ़ना, या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को केवल आंखों में डालें। उपयोग से पहले हाथ धोएं। ड्रॉपर की नोक को आंख या किसी सतह से न छुएं। कॉन्टैक्ट लेंस निकालकर ही डालें और 10-15 मिनट बाद ही वापस लगाएं। 3-5 दिन से ज्यादा लगातार इस्तेमाल न करें। धुंधली दृष्टि या नींद आने पर वाहन न चलाएं।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 analar eye drop Uses & Benefits

[{"condition":"Allergic conjunctivitis","description":"Relieves redness, itching, and watering of the eyes caused by allergies.","evidence":"Well-established"},{"condition":"Seasonal allergic eye symptoms","description":"Provides temporary relief from eye irritation during pollen or dust seasons.","evidence":"Well-established"},{"condition":"Non-infectious eye irritation","description":"Soothes mild irritation from smoke, wind, or other environmental factors.","evidence":"Commonly used"}]

Off-label uses: [{"condition":"Minor eye redness from fatigue","description":"Sometimes used to reduce cosmetic redness, but not a primary approved use.","evidence":"Limited"}]

Primary treatment for: Allergic conjunctivitis

Also treats: Seasonal allergic eye symptoms, Non-infectious eye irritation

📋 Drug Information

Generic Name(s)Naphazoline + Chlorpheniramine Maleate
Brand NameAndre Plus Eye Drops
ManufacturerPharmtak Ophtalmics India Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOPHTHAL
Action ClassOphthalmic decongestant and antihistamine
Route of AdministrationOphthalmic (topical eye drops)
StorageStore at room temperature (15-30°C). Protect from light and moisture. Keep the bottle tightly closed when not in use.
Shelf LifeRefer to the packaging for the expiry date. Do not use after the expiry date.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Use this medicine only for short-term relief, not more than 3-5 days consecutively.
2
Remove contact lenses before applying and wait 10-15 minutes before reinserting.
3
Do not touch the dropper tip to your eye or any surface to avoid contamination.
4
If you have glaucoma, high blood pressure, or heart disease, consult your doctor before use.
5
Avoid driving or operating machinery if you experience blurred vision or drowsiness.
6
Do not share your eye drops with anyone else.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Eye redness
This medicine is commonly used for allergic redness.
Likely Use
Eye itching
The antihistamine component helps relieve itching.
Likely Use
Eye pain
Eye pain may indicate a serious condition; consult a doctor.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionSystemic absorption after topical ocular administration is minimal but can occur, especially if the tear duct is not compressed after instillation.
DistributionNot established from the available information.
Protein BindingNot established from the available information.
MetabolismNot established from the available information.
Half-LifeNot established from the available information.
ExcretionNot established from the available information.
BioavailabilityNot established from the available information.
Onset of ActionRedness reduction typically begins within a few minutes after instillation.
Peak Plasma TimeNot established from the available information.
Duration of ActionSymptomatic relief usually lasts for 4 to 6 hours, but this can vary.

How It Works

This medicine works through two complementary mechanisms. Naphazoline, an imidazoline derivative, directly stimulates alpha-adrenergic receptors on the blood vessels of the conjunctiva, causing them to narrow. This reduces blood flow and quickly diminishes redness and swelling. Chlorpheniramine maleate is a first-generation antihistamine that competitively blocks histamine H1 receptors on cells in the eye, preventing histamine from triggering itching, vasodilation, and increased permeability. The combination addresses both the vascular and allergic components of eye irritation.

Mechanism Steps

1
Alpha-adrenergic stimulation: Naphazoline binds to alpha receptors on conjunctival blood vessels, causing vasoconstriction and reducing redness.
2
Histamine H1 receptor blockade: Chlorpheniramine maleate blocks histamine H1 receptors, preventing histamine-mediated itching and vascular leakage.
3
Rapid symptomatic relief: The combined actions reduce redness, itching, and swelling within minutes of application.

💡 How to Take analar eye drop

Strength: Eye drops containing naphazoline 0.05% w/v and chlorpheniramine maleate 0.01% w/v.

1Wash your hands thoroughly with soap and water.
2Shake the bottle gently before use.
3Tilt your head back and pull down your lower eyelid to form a small pocket.
4Look up and squeeze one drop into the pocket. Avoid touching the dropper tip to your eye.
5Close your eye gently for 1-2 minutes and press the inner corner of your eye with a finger to prevent drainage.
6Wipe away any excess liquid with a clean tissue.
7Replace the cap tightly and wash your hands again.

Dosage Information

Adult DosageThe usual adult dose is one drop in the affected eye(s) up to four times daily, or as directed by your doctor. Do not use for more than 3 to 5 days consecutively unless advised. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine. Use with caution and follow doctor's advice.
Renal ImpairmentNot established from the available information. Consult your doctor.
Hepatic ImpairmentNot established from the available information. Consult your doctor.
Maximum Daily DoseDo not exceed the dose prescribed by your doctor. Typically, no more than 4 drops per eye per day.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of analar eye drop

✅ Common Side Effects

Temporary stinging or burning (Common (5-10%))
Usually resolves within a minute. If it persists, consult your doctor.
Blurred vision (Common (5-10%))
Wait until vision clears before driving or operating machinery.
Headache (Uncommon (1-5%))
Rest and stay hydrated. Consult doctor if severe or persistent.
Drowsiness (Uncommon (1-5%))
Avoid driving or operating heavy machinery until you know how it affects you.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help immediately if you experience swelling of face, lips, throat, or difficulty breathing.
Rebound conjunctival hyperemia (Uncommon with prolonged use)
Stop using the medicine and consult your eye doctor if redness worsens or persists.
Increased intraocular pressure (Rare)
Consult an ophthalmologist if you have glaucoma or experience eye pain and vision changes.

⚠️ Rare Side Effects

Systemic hypertension
Monitor blood pressure if you have hypertension. Seek medical attention if severe.
Tachycardia or palpitations
Consult a doctor if you notice a fast or irregular heartbeat.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAO inhibitors Major
Tricyclic antidepressants Moderate
Other antihistamines Moderate
Beta-blockers Minor

🚨 Major Interactions

  • MAO inhibitors

⚡ Moderate Interactions

  • Tricyclic antidepressants
  • Other antihistamines or CNS depressants

🍷 Alcohol Interaction

Alcohol may increase drowsiness caused by the antihistamine component. Avoid or limit alcohol while using this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to naphazoline, chlorpheniramine, or any ingredient","Narrow-angle glaucoma","Severe cardiovascular disease including uncontrolled hypertension","Use in children below the age recommended by a doctor"]

⚠️ Warnings & Precautions

["Do not use for more than 3 to 5 days without medical advice.","Remove contact lenses before use and wait 10-15 minutes before reinserting.","May cause drowsiness; avoid driving if affected.","Do not touch dropper tip to any surface to avoid contamination.","Consult doctor if you have glaucoma, high blood pressure, heart disease, or thyroid problems."]

🤱 Lactation Safety

It is not known whether this medicine passes into breast milk in significant amounts. Consult your doctor before using while breastfeeding.

💊 Overdose Management

Overdose from topical eye use is unlikely. If accidentally ingested, seek immediate medical attention. Symptoms of overdose may include drowsiness, slow heart rate, low blood pressure, or difficulty breathing. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Use this medicine only in the eye and only as directed by your doctor. Wash your hands before and after each use. Do not touch the dropper tip to your eye, eyelid, or any surface to avoid contamination. Remove soft contact lenses before applying the drops and wait at least 10 to 15 minutes before reinserting them. Do not use this medicine for more than 3 to 5 days in a row unless your doctor tells you otherwise, because longer use can cause rebound redness. Avoid driving or operating heavy machinery if you experience blurred vision or drowsiness after using the drops. Do not share your eye drops with anyone else. Keep the bottle tightly closed and out of reach of children. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before using this medicine. If you have glaucoma, high blood pressure, heart disease, or an overactive thyroid, tell your doctor before using this product.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the effects of this medicine, especially drowsiness and cardiovascular effects. Use with caution and follow doctor's advice.

🤰 Pregnancy Planning (TTC)

Consult your doctor before using this medicine if you are planning pregnancy or are pregnant. The safety profile is not well established.

🏥 Post-Surgery Considerations

Consult your eye surgeon before using this medicine after eye surgery, as it may interfere with healing or increase pressure.

🦷 Dental Procedures

No specific considerations. Inform your dentist if you are using this medicine.

💚 Lifestyle Tips for Better Results

🏃
Avoid rubbing your eyes to prevent irritation.
🥗
Wash your hands frequently to reduce allergen contact.
😴
Use sunglasses to protect eyes from wind and dust.
💧
Keep windows closed during high pollen seasons.
🧘
Use air purifiers to reduce indoor allergens.

🏋️ Exercise Considerations

No specific exercise restrictions, but avoid swimming or activities that may expose eyes to contaminants while using this medicine.

🥗 Diet Recommendations

Include omega-3 rich foods like fish to support eye health.
Stay hydrated to maintain tear production.
Reduce intake of processed foods that may worsen inflammation.

💼 Impact on Daily Work & Life

May cause temporary blurred vision or drowsiness, affecting driving or operating machinery. Avoid these activities until you know how the medicine affects you.

🛑 When to Stop This Medicine

Stop using this medicine if symptoms worsen, if you experience severe side effects, or after the recommended short-term use period. Consult your doctor before stopping if you have been using it for a longer duration.

📅 Long-Term Use Effects

Prolonged use beyond 3-5 days can lead to rebound conjunctival hyperemia, where the eye becomes redder when the medicine is stopped. It may also increase the risk of systemic effects. Regular monitoring by an eye doctor is advised if long-term use is necessary.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Cold compresses

Can help reduce eye puffiness and soothe irritation.

Evidence: Well-established
Avoidance of allergens

Reducing exposure to pollen, dust, or pet dander can prevent symptoms.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines. Consult your doctor if you have concerns.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with the prescription label intact. Keep a copy of your prescription with you. Store at room temperature and protect from direct sunlight. If traveling across time zones, continue your regular dosing schedule as prescribed. Declare it at customs if required. Do not leave it in a hot car.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 32-year-old woman with seasonal eye allergies
She experienced itchy, red, watery eyes every spring. Her doctor prescribed this medicine. She used it for 3 days and got significant relief. She was advised not to use it continuously and to remove her contact lenses before application.
💡 Lesson: Short-term use as directed provides effective relief without rebound redness.
👤 A 45-year-old man with red eyes from dust exposure
He used this medicine for quick relief but continued it for 2 weeks. His eyes became redder when he stopped. His doctor explained rebound hyperemia and advised gradual withdrawal and alternative treatment.
💡 Lesson: Prolonged use can cause rebound redness; always follow the recommended duration.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Redness relief usually begins within a few minutes after instillation.

Q: How long can I use this medicine?

A: Do not use for more than 3 to 5 days consecutively unless directed by your doctor.

Q: Is it safe for children?

A: Pediatric dosing is not established. Consult a pediatrician.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this medicine long-term?
  • Will it affect my vision?
  • Can I drive after using this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while using this?

🔄 Substitutes for analar eye drop

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be used indefinitely for red eyes.
    Fact: Prolonged use can cause rebound redness and should be limited to 3-5 days unless directed by a doctor.
  • Myth: It is safe to use anyone else's eye drops.
    Fact: Sharing eye drops can spread infection and is not recommended.

📊 Comparison with Similar Medicines

[{"feature":"Naphazoline + Chlorpheniramine","this_medicine":"Combination provides both redness and itch relief.","alternative":"Single-ingredient drops may only address one symptom."}]

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