amyclox-lb 125mg/125mg/60millionspores tablet - Amoxycillin (125mg) + Cloxacillin (125mg) medicine

Almox C Tablet: Complete Guide to Uses, Side Effects, and Safety

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🏭 Ind Swift Laboratories Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for susceptible bacterial infections.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of face, lips, or throat
  • Severe or persistent diarrhea
  • Blood in stool or vomit
  • Yellowing of skin or eyes
  • Unusual bleeding or bruising
  • Decreased urine output
  • Seizures

If experiencing severe symptoms, call emergency services immediately.

What is amyclox-lb 125mg/125mg/60millionspores tablet used for?

This medicine is a combination antibiotic containing Amoxycillin and Cloxacillin, used to treat bacterial infections of the skin, respiratory tract, and other sites. It works by killing bacteria and should be taken exactly as prescribed.

  • Generic Name: Amoxycillin + Cloxacillin
  • Manufacturer: Ind Swift Laboratories Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 amyclox-lb 125mg/125mg/60millionspores tablet के बारे में (Hindi Summary)

उपयोग: यह दवा अमोक्सिसिलिन और क्लोक्सासिलिन का संयोजन है, जिसका उपयोग बैक्टीरियल संक्रमणों के इलाज के लिए किया जाता है। यह त्वचा, श्वसन पथ, दांतों और अन्य संक्रमणों में प्रभावी है। यह बैक्टीरिया की कोशिका भित्ति को नष्ट करके उन्हें मार देती है। इसे डॉक्टर के निर्देशानुसार ही लें और पूरा कोर्स पूरा करें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, पेट दर्द और त्वचा पर चकत्ते शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी, गंभीर दस्त, या यकृत की समस्या हो सकती है। यदि कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खाने के साथ लें ताकि पेट खराब न हो। पूरा कोर्स पूरा करें, बीच में न छोड़ें। शराब न पिएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। दवा को बच्चों से दूर रखें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 amyclox-lb 125mg/125mg/60millionspores tablet Uses & Benefits

[{"condition":"Skin and soft tissue infections","description":"Effective against infections caused by Staphylococcus aureus and Streptococcus species, including cellulitis, impetigo, and wound infections.","evidence":"Well-established"},{"condition":"Respiratory tract infections","description":"Used for upper and lower respiratory tract infections such as pharyngitis, tonsillitis, sinusitis, and community-acquired pneumonia when caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Urinary tract infections","description":"May be used for uncomplicated urinary tract infections caused by susceptible organisms, though other antibiotics are often preferred.","evidence":"Moderate"},{"condition":"Dental infections","description":"Prescribed for dental abscesses and periodontal infections caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Bone and joint infections","description":"May be used in combination with other antibiotics for osteomyelitis and septic arthritis caused by susceptible staphylococci.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Eradication of Helicobacter pylori","description":"Amoxycillin is part of some regimens, but the combination with Cloxacillin is not standard.","evidence":"Limited"},{"condition":"Lyme disease","description":"Amoxycillin is used, but Cloxacillin is not typically included.","evidence":"Limited"}]

Primary treatment for: Bacterial infections

Also treats: Skin and soft tissue infections, Respiratory tract infections, Dental infections, Urinary tract infections, Bone and joint infections

📋 Drug Information

Generic Name(s)Amoxycillin + Cloxacillin
Brand NameAmyclox-LB Capsule
ManufacturerInd Swift Laboratories Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassPenicillin antibiotics, beta-lactamase resistant combination
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and direct sunlight. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Complete the full prescribed course even if you feel better.
3
Do not share this medicine with others.
4
Avoid alcohol while taking this medicine.
5
Inform your doctor if you have kidney or liver disease.
6
Report any rash, difficulty breathing, or severe diarrhea immediately.
7
Take at evenly spaced intervals for best effect.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Skin infection
This medicine is commonly prescribed for this.
Likely Use
Sore throat
May be used if bacterial pharyngitis is suspected.
Likely Use
Common cold
This medicine is not effective against viral infections.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAmoxycillin and Cloxacillin are both absorbed from the gastrointestinal tract after oral administration. Amoxycillin is more rapidly and completely absorbed than Cloxacillin. Food may slightly reduce the rate but not the extent of absorption. The presence of food in the stomach can decrease peak concentrations of Cloxacillin.
DistributionBoth Amoxycillin and Cloxacillin distribute widely into body tissues and fluids, including skin, muscle, bone, and synovial fluid. They cross the placenta and are excreted in breast milk. Cloxacillin is highly protein-bound, which limits its distribution to some extent.
Protein BindingAmoxycillin is approximately 17-20% protein-bound. Cloxacillin is approximately 94-97% protein-bound, primarily to albumin.
MetabolismAmoxycillin is partially metabolized in the liver to inactive penicilloic acid. Cloxacillin is also metabolized in the liver, primarily by hydrolysis and oxidation.
Half-LifeThe elimination half-life of Amoxycillin is approximately 1 to 1.5 hours. The elimination half-life of Cloxacillin is approximately 0.5 to 1 hour. These may be prolonged in patients with renal impairment.
ExcretionBoth Amoxycillin and Cloxacillin are excreted primarily unchanged in the urine via glomerular filtration and tubular secretion. A small amount is excreted in bile and feces.
BioavailabilityAmoxycillin has a bioavailability of approximately 80-90% after oral administration. Cloxacillin has a bioavailability of approximately 50-70% after oral administration.
Onset of ActionThe onset of antibacterial action begins within 1 to 2 hours after oral administration, corresponding to peak plasma concentrations.
Peak Plasma TimePeak plasma concentrations of Amoxycillin are reached approximately 1 to 2 hours after oral administration. Peak plasma concentrations of Cloxacillin are reached approximately 0.5 to 1 hour after oral administration.
Duration of ActionThe antibacterial effect typically lasts for 6 to 8 hours after a single dose, depending on the susceptibility of the organism and the dose administered.

How It Works

This medicine combines two penicillin antibiotics that inhibit bacterial cell wall synthesis. Amoxycillin and Cloxacillin both bind to penicillin-binding proteins (PBPs) located inside the bacterial cell wall. This binding inhibits the transpeptidation reaction that cross-links peptidoglycan chains, which are essential for cell wall strength and rigidity. As a result, the bacterial cell wall becomes weakened, and the cell undergoes lysis and death, especially in actively dividing bacteria. Cloxacillin is resistant to hydrolysis by penicillinase enzymes produced by certain staphylococci, allowing it to be effective against penicillinase-producing Staphylococcus aureus. Amoxycillin has a broader spectrum but is susceptible to penicillinase. The combination provides coverage against both penicillinase-producing and non-producing bacteria.

Mechanism Steps

1
Binding to penicillin-binding proteins: Amoxycillin and Cloxacillin bind to specific penicillin-binding proteins (PBPs) on the bacterial cell membrane.
2
Inhibition of cell wall cross-linking: This binding inhibits the transpeptidase enzyme responsible for cross-linking peptidoglycan strands in the bacterial cell wall.
3
Weakening of cell wall: Without proper cross-linking, the cell wall becomes weak and cannot withstand osmotic pressure.
4
Bacterial lysis and death: The weakened cell wall leads to cell lysis and death, especially in rapidly dividing bacteria.

💡 How to Take amyclox-lb 125mg/125mg/60millionspores tablet

Strength: Tablet containing Amoxycillin 125 mg and Cloxacillin 125 mg.

1Take this medicine with a full glass of water.
2Take with food to reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Take at evenly spaced intervals as prescribed.
5Complete the full course even if you feel better.
6Do not share this medicine with others.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one tablet (Amoxycillin 125 mg + Cloxacillin 125 mg) taken orally every 6 to 8 hours, or as prescribed by your doctor. The dose may be increased for severe infections. The duration of treatment depends on the type and severity of infection, typically 5 to 10 days. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-medicate.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing based on weight and infection severity.
Elderly DosageElderly patients may have reduced renal function and may require dose adjustment. Use with caution and monitor renal function. Dose must be individualized by a qualified clinician.
Renal ImpairmentIn patients with renal impairment (creatinine clearance <30 mL/min), dose reduction or increased dosing interval may be necessary. Consult your doctor for specific dosing recommendations.
Hepatic ImpairmentIn patients with hepatic impairment, use with caution and monitor liver function. Dose adjustment may be necessary. Consult your doctor.
Maximum Daily DoseThe maximum recommended daily dose is not established from available information. Follow your doctor's prescription.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
No significant interaction
Not known to interact with penicillins.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of amyclox-lb 125mg/125mg/60millionspores tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. If it persists, consult your doctor.
Diarrhea (Common (5-10%))
Stay hydrated. If diarrhea is severe or persistent, contact your doctor.
Vomiting (Common (5-10%))
Take with food and avoid large meals. Consult doctor if vomiting continues.
Skin rash (Uncommon (1-5%))
Stop the medicine and consult your doctor immediately if rash appears.
Stomach pain (Common (5-10%))
Take with food. If pain is severe, seek medical advice.

🚨 Serious Side Effects

Anaphylaxis (Rare (<0.1%))
Seek emergency medical help immediately if you experience difficulty breathing, swelling of face or throat, or a sudden drop in blood pressure.
Clostridioides difficile-associated diarrhea (Rare (<0.1%))
Contact your doctor if you develop severe or persistent diarrhea, abdominal cramps, or fever.
Hepatotoxicity (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe abdominal pain to your doctor immediately.
Blood dyscrasias (Rare (<0.1%))
If you notice unusual bleeding, bruising, or signs of infection, seek medical attention.
Seizures (Very rare (<0.01%))
Seek immediate medical attention if seizures occur, especially in patients with renal impairment.

⚠️ Rare Side Effects

Interstitial nephritis
Report decreased urine output, swelling, or fatigue to your doctor.
Serum sickness-like reaction
Seek medical attention for fever, joint pain, and rash.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Methotrexate Major
Probenecid Moderate
Allopurinol Moderate
Oral contraceptives Moderate
Tetracyclines Moderate
Antacids Minor
Food Minor

🚨 Major Interactions

  • Warfarin
  • Methotrexate
  • Probenecid

⚡ Moderate Interactions

  • Allopurinol
  • Oral contraceptives
  • Tetracyclines

🍷 Alcohol Interaction

Alcohol may worsen gastrointestinal side effects such as nausea and diarrhea. It is advisable to avoid alcohol while taking this medicine to reduce the risk of stomach upset and to support recovery from infection.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to penicillins or cephalosporins.","History of severe allergic reaction (e.g., anaphylaxis) to beta-lactam antibiotics.","Infectious mononucleosis (risk of rash).","Concurrent use with live typhoid vaccine (may reduce efficacy)."]

⚠️ Warnings & Precautions

["Use with caution in patients with renal impairment; dose adjustment may be needed.","Use with caution in patients with hepatic impairment; monitor liver function.","May cause false-positive results in urine glucose tests using copper reduction methods.","Prolonged use may lead to superinfection with resistant organisms or fungi.","Ensure adequate hydration during treatment.","Do not use for viral infections; it is ineffective and promotes resistance.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.","Avoid alcohol to reduce gastrointestinal side effects."]

🤱 Lactation Safety

Amoxycillin and Cloxacillin are excreted in breast milk in small amounts. They are generally considered safe during breastfeeding, but monitor the infant for diarrhea, thrush, or rash. Consult your doctor before use.

💊 Overdose Management

Overdose may cause nausea, vomiting, diarrhea, and electrolyte imbalance. In severe cases, especially in renal impairment, seizures may occur. Treatment is symptomatic and supportive. Maintain adequate hydration. Hemodialysis may be considered in severe cases to remove Amoxycillin from the blood. Contact a poison control center or emergency department immediately if overdose is suspected.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop treatment early, even if you feel better, as this can lead to antibiotic resistance and recurrence of infection. Take this medicine with food to reduce stomach upset. Swallow the tablet whole with a glass of water. Do not crush or chew the tablet unless your doctor advises otherwise. Inform your doctor if you have a history of allergies, kidney or liver disease, or if you are pregnant or breastfeeding. Avoid alcohol while taking this medicine as it may worsen side effects. Do not share this medicine with others, even if they have similar symptoms. Keep out of reach of children. Store at room temperature away from moisture and heat. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have reduced renal function and are at higher risk of side effects. Dose adjustment may be necessary. Monitor renal function.

🤰 Pregnancy Planning (TTC)

Consult your doctor before taking this medicine if you are planning pregnancy. It is generally considered safe, but only use if clearly needed.

🏥 Post-Surgery Considerations

This medicine may be prescribed to prevent or treat surgical site infections. Follow your surgeon's instructions.

🦷 Dental Procedures

This medicine is often prescribed for dental infections. Inform your dentist if you are taking it before any dental procedure.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy diet to support recovery.
🥗
Stay well hydrated.
😴
Get adequate rest.
💧
Practice good hygiene to prevent infection spread.
🧘
Avoid alcohol.
🌞
Complete the full course of antibiotics.

🏋️ Exercise Considerations

No specific exercise restrictions, but if you feel dizzy or weak, avoid strenuous activities until you feel better.

🥗 Diet Recommendations

Include probiotics like yogurt to prevent diarrhea.
Stay hydrated.
Eat light, easily digestible meals.
Avoid spicy and oily foods if you have stomach upset.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or fatigue in some people. If affected, avoid driving or operating heavy machinery until you know how it affects you.

🛑 When to Stop This Medicine

Stop taking this medicine only after completing the full prescribed course or as directed by your doctor. Do not stop early even if you feel better, as this can lead to recurrence and resistance.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to antibiotic resistance, fungal superinfections, and rarely, blood dyscrasias or liver toxicity. Regular monitoring may be required if used for prolonged periods. It should only be used for the prescribed duration.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Other antibiotics

Depending on the infection and susceptibility, other antibiotics like cephalosporins or macrolides may be used.

Evidence: Well-established
Topical antibiotics

For minor skin infections, topical antibiotics may be sufficient.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine may reduce the efficacy of live bacterial vaccines like typhoid vaccine. Avoid concurrent use.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing intervals as advised by your doctor. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with a skin infection
He was prescribed this medicine for a boil on his leg. He took it with food as advised and completed the 7-day course. The infection cleared up without any major side effects.
💡 Lesson: Taking the medicine with food and completing the course led to successful treatment.
👤 A 50-year-old woman with a dental abscess
She experienced nausea initially but it subsided after taking the tablet with meals. She completed the course and her dental infection resolved.
💡 Lesson: Taking with food can minimize gastrointestinal side effects.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 1-2 days, but it is important to complete the full course.

Q: Can I take it with food?

A: Yes, take it with food to reduce stomach upset.

Q: What if I miss a dose?

A: Take it as soon as you remember, but if it's almost time for the next dose, skip the missed dose. Do not double dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for amyclox-lb 125mg/125mg/60millionspores tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Antibiotics can cure viral infections like the common cold.
    Fact: This medicine is effective only against bacterial infections. It does not treat viral infections.
  • Myth: You can stop taking antibiotics once you feel better.
    Fact: You must complete the full prescribed course to prevent recurrence and resistance.
  • Myth: Antibiotics can be shared with others.
    Fact: Never share antibiotics; they are prescribed for a specific infection and person.

🔄 Alternative Options

Generic Alternatives

  • Amoxycillin and Cloxacillin combination tablets from other manufacturers.

Brand Alternatives

  • Almox C tablet

📊 Comparison with Similar Medicines

[{"medicine":"Amoxycillin + Cloxacillin","composition":"Amoxycillin 125 mg + Cloxacillin 125 mg","uses":"Skin, respiratory, dental infections","notes":"Combination covers penicillinase-producing staphylococci."},{"medicine":"Amoxycillin + Clavulanic acid","composition":"Amoxycillin 500 mg + Clavulanic acid 125 mg","uses":"Broad-spectrum infections","notes":"Clavulanic acid inhibits beta-lactamase, broader coverage."},{"medicine":"Cefuroxime axetil","composition":"Cefuroxime 250 mg","uses":"Respiratory, skin infections","notes":"Second-generation cephalosporin, alternative for penicillin allergy."}]

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