Amwin's Fungisure-IT 200 Capsule - Uses, Price, Side Effects
What is amwin's fungisure-it 200 capsule used for?
Amwin's Fungisure-IT 200 Capsule contains Itraconazole, an antifungal medication used to treat infections caused by fungi and yeasts, such as athlete's foot, ringworm, and systemic fungal infections. It works by inhibiting the synthesis of ergosterol, a vital component of fungal cell membranes, leading to cell death.
- Generic Name: Itraconazole
- Manufacturer: Amwin Pharmaceuticals
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ amwin's fungisure-it 200 capsule Uses & Benefits
Onychomycosis, dermatophytosis, candidiasis, histoplasmosis, blastomycosis, aspergillosis.
Off-label uses: Coccidioidomycosis, sporotrichosis, chromoblastomycosis, prophylaxis in immunocompromised patients.
๐ Drug Information
| Generic Name(s) | Itraconazole |
| Brand Name | Alcros 100 Capsule |
| Manufacturer | Amwin Pharmaceuticals |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | OPHTHAL |
| Action Class | Fungal ergosterol synthesis inhibitor |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits fungal cytochrome P450 14ฮฑ-demethylase, blocking ergosterol synthesis and disrupting fungal cell membrane.
Mechanism Steps
๐ก How to Take amwin's fungisure-it 200 capsule
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of amwin's fungisure-it 200 capsule
โ Common Side Effects
- Nausea
- Abdominal pain
- Diarrhea
- Headache
- Dizziness
- Rash
๐จ Serious Side Effects
- Hepatotoxicity
- Congestive heart failure
- QT prolongation
- Torsades de pointes
- Stevens-Johnson syndrome
โ ๏ธ Rare Side Effects
- Peripheral neuropathy
- Adrenal suppression
- Hypokalemia
- Gynecomastia
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Cisapride | Major | Risk of cardiac arrhythmias |
| Statins | Moderate | Increased risk of myopathy |
๐จ Major Interactions
- CYP3A4 substrates (e.g., midazolam, triazolam)
- HMG-CoA reductase inhibitors (e.g., simvastatin, lovastatin)
- Ergot alkaloids
- Cisapride
- Pimozide
- Quinidine
- Dofetilide
- Lovastatin
- Simvastatin
โก Moderate Interactions
- Warfarin
- Oral hypoglycemics
- Calcium channel blockers
- Digoxin
- Cyclosporine
- Tacrolimus
- Sirolimus
- Carbamazepine
- Phenytoin
- Rifampin
- Isoniazid
- Antacids
- H2 blockers
- Proton pump inhibitors
โน๏ธ Minor Interactions
- Corticosteroids
- Benzodiazepines (e.g., alprazolam)
- Oral contraceptives
๐ฝ๏ธ Food Interactions
Absorption increased with acidic beverages (e.g., cola) and food; avoid grapefruit juice.
๐ท Alcohol Interaction
Avoid alcohol due to potential hepatotoxicity.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to itraconazole or excipients; concomitant use with CYP3A4 substrates with narrow therapeutic index; ventricular dysfunction; pregnancy (category C).
๐ Monitoring Parameters
Liver function tests (ALT, AST), serum potassium, ECG (QT interval), therapeutic drug monitoring if needed.
๐คฑ Lactation Safety
Excreted in breast milk; use with caution.
๐ Overdose Management
Supportive care; no specific antidote; gastric lavage if recent; monitor liver function and ECG.
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for amwin's fungisure-it 200 capsule
View AllAlternative brands with exact same active ingredient (Itraconazole (200mg)):
-
itrazeal 200mg capsuleGlantis Pharmaceutical โน20.63 90.6% CHEAPER
-
itrapro 200mg capsuleKitnix Pvt Ltd โน33.98 84.6% CHEAPER
-
davaindia itraconazole 200mg capsuleDavaindia Generic Pharmacy โน39.38 82.1% CHEAPER
-
fungizee 200 capsuleZeelab Pharmacy Pvt Ltd โน40.00 81.8% CHEAPER
-
candimore 200mg capsuleMorepen Laboratories Ltd โน45.00 79.5% CHEAPER
-
itrobid 200mg capsuleEuro Organics โน45.94 79.1% CHEAPER
-
itraks 200mg capsuleAxis Life Science Pvt Ltd โน48.75 77.8% CHEAPER
-
itrapic 200mg capsuleAtopic Laboratories โน60.94 72.3% CHEAPER
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itrason 200 capsuleUnison Pharmaceuticals Pvt Ltd โน64.09 70.9% CHEAPER
-
itrapuri 200mg capsuleRavian Life Science Pvt Ltd โน65.63 70.2% CHEAPER
Medical Note: Always consult your doctor before switching medications.