ampy c 250mg/500mg tablet - Ampicillin (250mg) + Cloxacillin (500mg) medicine

Ampy C 250mg/500mg Tablet - Uses, Price, Side Effects

4.6 (16 reviews)
๐Ÿญ Global Medisciences Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 21, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 21, 2026

What is ampy c 250mg/500mg tablet used for?

Ampy C 250mg/500mg Tablet is a combination antibiotic containing Ampicillin and Cloxacillin. It is used to treat bacterial infections such as respiratory tract infections, skin infections, and urinary tract infections. Ampicillin kills bacteria by inhibiting cell wall synthesis, while Cloxacillin is effective against penicillinase-producing bacteria. Take as prescribed by your doctor.

  • Generic Name: Ampicillin + Cloxacillin
  • Manufacturer: Global Medisciences Ltd
  • Form: Allopathy
  • Pregnancy Category: B
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š ampy c 250mg/500mg tablet Uses & Benefits

Respiratory tract infections, urinary tract infections, skin and soft tissue infections, bone and joint infections

Off-label uses: Prophylaxis in dental procedures, Endocarditis prophylaxis

๐Ÿ“‹ Drug Information

Generic Name(s)Ampicillin + Cloxacillin
Brand NameAmpoxin 500 Capsule
ManufacturerGlobal Medisciences Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassPenicillinase-resistant penicillin combination
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed from the gastrointestinal tract
DistributionDistributed widely in body tissues and fluids, including pleural, peritoneal, and synovial fluids
Protein BindingAmpicillin: 15-25%; Cloxacillin: 90-95%
MetabolismPartially hepatic
Half-LifeAmpicillin: 1-1.5 hours; Cloxacillin: 0.5-1 hour
ExcretionRenal (tubular secretion and glomerular filtration)
BioavailabilityAmpicillin: 50-60%; Cloxacillin: 50-70%
Onset of Action1-2 hours
Peak Plasma Time1-2 hours
Duration of Action6-8 hours

How It Works

Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to cell lysis

Mechanism Steps

1Penetration through bacterial cell wall via porins
2Binding to penicillin-binding proteins (PBPs) on the inner membrane
3Inhibition of transpeptidase activity, preventing cross-linking of peptidoglycan

๐Ÿ’ก How to Take ampy c 250mg/500mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of ampy c 250mg/500mg tablet

โœ… Common Side Effects

  • Diarrhea
  • Nausea
  • Vomiting
  • Rash
  • Urticaria

๐Ÿšจ Serious Side Effects

  • Anaphylaxis
  • Pseudomembranous colitis
  • Stevens-Johnson syndrome
  • Seizures

โš ๏ธ Rare Side Effects

  • Hemolytic anemia
  • Agranulocytosis
  • Interstitial nephritis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Methotrexate Major Increased methotrexate toxicity
Probenecid Moderate Decreased renal excretion of ampicillin
Oral contraceptives Minor Reduced contraceptive efficacy

๐Ÿšจ Major Interactions

  • Methotrexate
  • Warfarin
  • Probenecid

โšก Moderate Interactions

  • Oral contraceptives
  • Allopurinol
  • Chloramphenicol

โ„น๏ธ Minor Interactions

  • Aminoglycosides
  • Tetracyclines

๐Ÿฝ๏ธ Food Interactions

Food may decrease absorption; take on empty stomach

๐Ÿท Alcohol Interaction

No known interaction

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category B

๐Ÿšซ Contraindications

Hypersensitivity to penicillins, cephalosporins, or any component

๐Ÿ“Š Monitoring Parameters

Renal function, hepatic function, complete blood count, signs of hypersensitivity

๐Ÿคฑ Lactation Safety

Excreted in breast milk in low concentrations; generally considered compatible

๐Ÿ’Š Overdose Management

Supportive care; hemodialysis may be considered

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

๐Ÿ”— View Profile

โญ User Reviews

Trusted Reviewer Jul 10, 2026

Found this to be a helpful product. Good results.

Regular Customer Jul 10, 2026

Found this to be a helpful product. Good results.

Regular Customer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Happy Patient Jul 10, 2026

Found this to be a helpful product. Good results.

Verified User Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

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