amps-s tablet - Silodosin (8mg) medicine

amps-s tablet

4.5 (16 reviews)
๐Ÿญ AMPS Biotech Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is amps-s tablet used for?

Avoprost (Silodosin) is used to treat UROLOGY. It contains Silodosin (8mg), which Selective antagonist of alpha-1A adrenergic receptors in the prostate, bladder b. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Silodosin
  • Manufacturer: AMPS Biotech Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š amps-s tablet Uses & Benefits

Treatment of signs and symptoms of benign prostatic hyperplasia (BPH).

Off-label uses: None well-established; may be used for ureteral stones (off-label).

๐Ÿ“‹ Drug Information

Generic Name(s)Silodosin
Brand NameAvoprost
ManufacturerAMPS Biotech Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassUROLOGY
Action ClassUroselective adrenergic receptor(ฮฑ1a) antagonist
Route of AdministrationOral
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration; peak plasma concentration reached within 2-6 hours.
DistributionVolume of distribution approximately 0.6 L/kg; extensively distributed to tissues.
Protein BindingApproximately 96-97% bound to plasma proteins, mainly albumin.
MetabolismExtensively metabolized in the liver via glucuronidation (UGT2B7) and to a lesser extent via CYP3A4; major metabolites are silodosin glucuronide and KMD-3213G.
Half-LifeApproximately 13-15 hours (parent drug); metabolites have longer half-lives.
ExcretionPrimarily excreted in feces (55%) and urine (34%); less than 1% excreted unchanged in urine.
BioavailabilityApproximately 32% (oral); food reduces bioavailability by about 20%.
Onset of ActionWithin 1-2 hours.
Peak Plasma Time2-6 hours post-dose.
Duration of ActionApproximately 24 hours.

How It Works

Selective antagonist of alpha-1A adrenergic receptors in the prostate, bladder base, and urethra, leading to relaxation of smooth muscle and improved urine flow.

Mechanism Steps

1Silodosin binds selectively to alpha-1A adrenergic receptors in the prostate, bladder base, and urethra.
2Antagonism of these receptors inhibits the action of norepinephrine.
3This leads to relaxation of smooth muscle in the prostate and bladder neck.

๐Ÿ’ก How to Take amps-s tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of amps-s tablet

โœ… Common Side Effects

  • Dizziness
  • Orthostatic hypotension
  • Nasal congestion
  • Diarrhea
  • Ejaculation disorders (retrograde ejaculation, decreased ejaculate volume)
  • Headache
  • Asthenia

๐Ÿšจ Serious Side Effects

  • Syncope
  • Priapism (rare)
  • Intraoperative floppy iris syndrome (IFIS) during cataract surgery
  • Allergic reactions (angioedema, rash)

โš ๏ธ Rare Side Effects

  • Hepatic enzyme elevation
  • Jaundice
  • Thrombocytopenia
  • Atrial fibrillation

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Ketoconazole Major Increased silodosin exposure; avoid coadministration.
Ritonavir Major Increased silodosin exposure; avoid coadministration.
Other alpha-blockers Major Additive hypotensive effects; avoid coadministration.
PDE5 inhibitors Major Increased risk of hypotension; avoid coadministration.
Diltiazem Moderate Increased silodosin exposure; monitor for adverse effects.
Antihypertensives Moderate Additive hypotensive effects; monitor blood pressure.
Digoxin Minor No significant interaction expected.
Warfarin Minor No significant interaction expected.

๐Ÿšจ Major Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, ritonavir, clarithromycin)
  • Alpha-blockers (e.g., tamsulosin, alfuzosin)
  • Phosphodiesterase-5 inhibitors (e.g., sildenafil, tadalafil)

โšก Moderate Interactions

  • Moderate CYP3A4 inhibitors (e.g., diltiazem, verapamil, erythromycin)
  • Antihypertensives (e.g., diuretics, beta-blockers, ACE inhibitors)

โ„น๏ธ Minor Interactions

  • Digoxin
  • Warfarin

๐Ÿฝ๏ธ Food Interactions

Food reduces bioavailability; take with food to minimize adverse effects.

๐Ÿท Alcohol Interaction

May increase risk of orthostatic hypotension and dizziness; avoid excessive alcohol.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to silodosin or any component; severe hepatic impairment; concomitant use with strong CYP3A4 inhibitors; history of orthostatic hypotension; severe renal impairment (CrCl <30 mL/min).

๐Ÿ“Š Monitoring Parameters

Blood pressure (especially orthostatic), symptoms of BPH, renal function, liver function tests.

๐Ÿคฑ Lactation Safety

Not indicated for women; unknown if excreted in human milk.

๐Ÿ’Š Overdose Management

Induce emesis or gastric lavage; administer supportive care; monitor blood pressure; vasopressors may be used for hypotension.

โฐ Missed Dose

Take missed dose as soon as remembered; if close to next dose, skip missed dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for amps-s tablet

View All

Alternative brands with exact same active ingredient (Silodosin (8mg)):

Medical Note: Always consult your doctor before switching medications.

โญ User Reviews

Regular Customer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Regular Customer Jul 10, 2026

Effective and reliable. Worked as expected.

Regular Customer Jul 10, 2026

Found this to be a helpful product. Good results.

Happy Patient Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Certified Buyer Jul 10, 2026

Effective and reliable. Worked as expected.

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