amnol 5 mg/50 mg tablet
What is amnol 5 mg/50 mg tablet used for?
Amlokind-AT Tablet (Amlodipine + Atenolol) is used to treat CARDIAC. It contains Amlodipine (5mg) + Atenolol (50mg), which Amlodipine inhibits calcium influx across cell membranes in vascular smooth musc. Always consult your doctor before use. Take as prescribed.
- Generic Name: Amlodipine + Atenolol
- Manufacturer: Exotic Laboratories Pvt Ltd
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ amnol 5 mg/50 mg tablet Uses & Benefits
Hypertension, angina pectoris (chronic stable angina, vasospastic angina)
๐ Drug Information
| Generic Name(s) | Amlodipine + Atenolol |
| Brand Name | Amlokind-AT Tablet |
| Manufacturer | Exotic Laboratories Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Calcium channel blocker + Beta blocker |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF), protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Amlodipine inhibits calcium influx across cell membranes in vascular smooth muscle and cardiac muscle, leading to vasodilation and reduced peripheral resistance. Atenolol selectively blocks beta-1 adrenergic receptors, decreasing heart rate, contractility, and cardiac output.
Mechanism Steps
๐ก How to Take amnol 5 mg/50 mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of amnol 5 mg/50 mg tablet
โ Common Side Effects
- Edema (ankle/foot)
- Headache
- Dizziness
- Fatigue
- Nausea
- Flushing
- Palpitations
- Bradycardia
- Cold extremities
๐จ Serious Side Effects
- Severe hypotension
- Heart failure exacerbation
- Bradyarrhythmias
- Bronchospasm
- Hepatotoxicity (rare)
- Stevens-Johnson syndrome (rare)
โ ๏ธ Rare Side Effects
- Gingival hyperplasia
- Leukopenia
- Thrombocytopenia
- Vasculitis
- Photosensitivity
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Verapamil | Major | Increased risk of bradycardia, heart block, and hypotension |
| Clonidine | Major | Rebound hypertension upon clonidine withdrawal |
| NSAIDs | Moderate | Reduced antihypertensive effect |
| Grapefruit juice | Minor | Increased amlodipine levels |
๐จ Major Interactions
- Beta blockers (other)
- Calcium channel blockers (verapamil, diltiazem)
- CYP3A4 inhibitors (ketoconazole, itraconazole, ritonavir)
- Clonidine
- Digitalis glycosides
โก Moderate Interactions
- NSAIDs
- Antihypertensives (additive effect)
- Insulin
- Oral hypoglycemics
- Anesthetics
โน๏ธ Minor Interactions
- Cimetidine
- Grapefruit juice (amlodipine)
- Antacids
๐ฝ๏ธ Food Interactions
Grapefruit juice may increase amlodipine levels; avoid excessive intake. Food does not significantly affect atenolol absorption.
๐ท Alcohol Interaction
Alcohol may enhance hypotensive effect; avoid excessive alcohol consumption.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to components, cardiogenic shock, severe bradycardia, heart block (2nd/3rd degree), sick sinus syndrome, severe hypotension, acute heart failure, asthma/COPD (atenolol), peripheral vascular disease (severe)
๐ Monitoring Parameters
Blood pressure, heart rate, ECG, serum electrolytes, renal function, hepatic function, blood glucose (in diabetics)
๐คฑ Lactation Safety
Low risk; both drugs excreted in breast milk in small amounts. Caution advised.
๐ Overdose Management
Supportive care; atropine for bradycardia, vasopressors for hypotension, calcium gluconate for calcium channel blocker overdose, glucagon for beta blocker overdose
โฐ Missed Dose
Take as soon as remembered if within 12 hours; skip if close to next dose. Do not double dose.
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Effective and reliable. Worked as expected.
Effective and reliable. Worked as expected.
Good quality medicine. Satisfied with the outcome.
This medicine was effective for me. I followed the doctor's advice.
Good quality medicine. Satisfied with the outcome.