amlowin at 5 mg/50 mg tablet - Amlodipine (5mg) + Atenolol (50mg) medicine

Amlokem AT 5 mg/50 mg Tablet: Comprehensive Medicine Guide

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🏭 Vintage Labs Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for hypertension and angina.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Very slow heart rate (below 50 beats per minute) or irregular heartbeat
  • Severe dizziness, fainting, or confusion
  • Difficulty breathing, wheezing, or chest tightness
  • Sudden swelling of face, lips, tongue, or throat
  • Chest pain that worsens or is not relieved by rest
  • Yellowing of skin or eyes (jaundice)
  • Decreased urine output or swelling in legs

If experiencing severe symptoms, call emergency services immediately.

What is amlowin at 5 mg/50 mg tablet used for?

This medicine is a combination of Amlodipine and Atenolol used to treat high blood pressure and prevent angina. It works by relaxing blood vessels and slowing the heart rate.

  • Generic Name: Amlodipine (5mg) + Atenolol (50mg)
  • Manufacturer: Vintage Labs Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 amlowin at 5 mg/50 mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा उच्च रक्तचाप (हाइपरटेंशन) और एंजाइना (सीने में दर्द) के इलाज के लिए इस्तेमाल की जाती है। यह रक्त वाहिकाओं को आराम देकर और हृदय की गति को धीमा करके रक्तचाप को कम करती है। यह उन वयस्कों के लिए है जिनका रक्तचाप एक दवा से नियंत्रित नहीं हो पाता। इसे डॉक्टर के निर्देशानुसार ही लें।

साइड इफेक्ट्स: आम दुष्प्रभावों में थकान, चक्कर आना, सिरदर्द, पैरों में सूजन, धीमी हृदय गति और ठंडे हाथ-पैर शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें गंभीर धीमी हृदय गति, हृदय रुकावट, सांस लेने में कठिनाई और गंभीर निम्न रक्तचाप शामिल हो सकते हैं। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अचानक बंद न करें, क्योंकि इससे एंजाइना या दिल का दौरा पड़ सकता है। शराब से बचें क्योंकि इससे चक्कर और निम्न रक्तचाप बढ़ सकता है। यदि आपको अस्थमा, मधुमेह, गुर्दे या यकृत की बीमारी है तो डॉक्टर को बताएं। नियमित रूप से रक्तचाप और हृदय गति की जांच कराएं।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 amlowin at 5 mg/50 mg tablet Uses & Benefits

  • [{"condition":"Hypertension","description":"This medicine is used to lower high blood pressure when a single agent is not effective.
  • It helps reduce the risk of stroke, heart attack, and kidney problems.","evidence":"Well-established"},{"condition":"Angina pectoris","description":"This medicine may be prescribed to prevent chest pain (angina) by reducing heart workload and improving blood flow to the heart.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes beta-blockers like Atenolol are used off-label to prevent migraines, but combination with Amlodipine is not standard.","evidence":"Limited"},{"condition":"Anxiety with palpitations","description":"Atenolol may be used off-label to reduce physical symptoms of anxiety such as rapid heartbeat, but this combination is not typical.","evidence":"Limited"}]

Primary treatment for: Hypertension

Also treats: Angina pectoris, Coronary artery disease

📋 Drug Information

Generic Name(s)Amlodipine (5mg) + Atenolol (50mg)
Brand Nameamlowin at 5 mg/50 mg tablet
ManufacturerVintage Labs Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day, preferably in the morning.
2
Monitor your blood pressure and heart rate regularly and keep a record.
3
Do not stop this medicine abruptly; consult your doctor before making any changes.
4
Avoid alcohol while taking this medicine to prevent dizziness and low blood pressure.
5
Inform your doctor if you experience persistent swelling of ankles, difficulty breathing, or very slow pulse.
6
If you have diabetes, monitor your blood sugar closely as Atenolol may mask hypoglycemia symptoms.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
High blood pressure
This medicine is commonly prescribed for this.
Likely Use
✅
Chest pain (angina)
This medicine helps prevent angina attacks.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary
❌
Headache
This medicine is not a primary headache treatment.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAmlodipine is well absorbed after oral administration, with peak plasma concentrations reached in 6 to 12 hours. Atenolol is incompletely absorbed (about 50%) from the gastrointestinal tract, with peak levels occurring 2 to 4 hours after ingestion.
DistributionAmlodipine is widely distributed in body tissues and is highly protein-bound. Atenolol has low protein binding and is distributed mainly in extracellular fluid, with low penetration into the brain.
Protein BindingAmlodipine is approximately 93% bound to plasma proteins. Atenolol is only about 3% bound to plasma proteins.
MetabolismAmlodipine is extensively metabolized in the liver, primarily by CYP3A4, to inactive metabolites. Atenolol is minimally metabolized in the liver and is primarily excreted unchanged by the kidneys.
Half-LifeThe elimination half-life of Amlodipine is approximately 30 to 50 hours. The elimination half-life of Atenolol is approximately 6 to 7 hours.
ExcretionAmlodipine is excreted mainly in the urine as metabolites. Atenolol is excreted primarily unchanged in the urine.
BioavailabilityThe oral bioavailability of Amlodipine is approximately 64% to 90%. The oral bioavailability of Atenolol is approximately 50% to 60%.
Onset of ActionAmlodipine: onset of antihypertensive effect is gradual, within 24 hours. Atenolol: onset of beta-blockade occurs within 1 hour after oral administration.
Peak Plasma TimeAmlodipine: 6 to 12 hours. Atenolol: 2 to 4 hours.
Duration of ActionAmlodipine: 24 hours. Atenolol: approximately 12 to 24 hours, allowing once-daily dosing.

How It Works

This medicine combines two antihypertensive agents with complementary mechanisms. Amlodipine is a dihydropyridine calcium channel blocker that inhibits the influx of calcium ions into vascular smooth muscle and cardiac muscle, causing peripheral arterial vasodilation and reducing peripheral vascular resistance. Atenolol is a cardioselective beta-1 adrenergic receptor blocker that reduces heart rate, myocardial contractility, and cardiac output. Together, they lower blood pressure and decrease myocardial oxygen demand.

Mechanism Steps

1
Calcium channel blockade by Amlodipine: Amlodipine blocks L-type calcium channels in vascular smooth muscle, preventing calcium entry and causing relaxation of blood vessels.
2
Vasodilation and reduced peripheral resistance: Relaxation of arterioles leads to decreased peripheral vascular resistance, lowering blood pressure.
3
Beta-1 receptor blockade by Atenolol: Atenolol selectively blocks beta-1 adrenergic receptors in the heart, reducing heart rate and contractility.
4
Reduced cardiac output and renin release: Atenolol decreases cardiac output and inhibits renin secretion from the kidneys, further lowering blood pressure.
5
Combined antihypertensive effect: The complementary actions of both drugs result in effective blood pressure control and reduced cardiac workload.

💡 How to Take amlowin at 5 mg/50 mg tablet

Strength: Tablet containing Amlodipine 5 mg and Atenolol 50 mg.

1Take this medicine orally with a glass of water.
2Swallow the tablet whole; do not crush or chew.
3Take it at the same time each day, preferably in the morning.
4You may take it with or without food, but taking it with food may reduce stomach upset.
5Do not stop taking this medicine without consulting your doctor.

Dosage Information

Adult DosageThe usual adult dose is one tablet (Amlodipine 5 mg + Atenolol 50 mg) once daily, preferably in the morning. Dose may be adjusted by your doctor based on blood pressure response and tolerability. Do not exceed the prescribed dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, especially dizziness and bradycardia. Start with lower doses and monitor closely. Dose must be individualized by a qualified clinician.
Renal ImpairmentAtenolol is excreted renally; dose adjustment is required in renal impairment. Amlodipine does not require adjustment. Consult your doctor for appropriate dosing.
Hepatic ImpairmentAmlodipine is metabolized hepatically; dose adjustment may be needed in hepatic impairment. Atenolol is minimally affected. Consult your doctor.
Maximum Daily DoseThe maximum recommended daily dose is one tablet (Amlodipine 5 mg + Atenolol 50 mg) once daily. Do not exceed without medical advice.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset and improves tolerability.
Grapefruit
Avoid
May increase Amlodipine levels and risk of side effects.
High-fat meals
No specific restriction
May slightly delay absorption but not clinically significant.

⏰ What to Do If You Miss a Dose

📌 Less than 12 hours have passed since the missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with your regular schedule.
📌 More than 12 hours have passed since the missed dose
→ Skip the missed dose and take the next dose at the regular time.
💡 Do not double the dose to catch up.

⚠️ Side Effects of amlowin at 5 mg/50 mg tablet

✅ Common Side Effects

Fatigue (Common (5-10%))
Usually improves with time. If persistent, consult your doctor.
Dizziness (Common (5-10%))
Rise slowly from sitting or lying position. Avoid driving if dizzy.
Headache (Common (5-10%))
May resolve on its own. Consult doctor if severe or persistent.
Peripheral edema (swelling of ankles/feet) (Common (5-10%))
Elevate legs when resting. Report to doctor if worsening.
Bradycardia (slow heart rate) (Common (5-10%))
Monitor pulse. If below 50 bpm or symptomatic, contact doctor.
Cold extremities (Common (5-10%))
Keep warm. Usually not dangerous.

🚨 Serious Side Effects

Severe bradycardia (Rare (<0.1%))
Seek immediate medical attention if you feel faint, very dizzy, or have a very slow pulse.
Heart block (Rare (<0.1%))
Requires urgent medical evaluation. Symptoms include fainting, severe dizziness, or palpitations.
Bronchospasm (Rare (<0.1%))
Seek immediate medical help if you experience difficulty breathing, wheezing, or chest tightness.
Severe hypotension (Rare (<0.1%))
Lie down and seek medical attention if you feel extremely dizzy or faint.
Worsening of heart failure (Rare (<0.1%))
Report increased shortness of breath, swelling, or fatigue to your doctor immediately.

⚠️ Rare Side Effects

Mood changes
Consult your doctor if you notice significant mood swings or depression.
Sleep disturbances
Discuss with your doctor if sleep problems persist.
Skin rash
Discontinue and consult doctor if rash develops.
Gastrointestinal disturbances
Take with food to minimize. Consult doctor if severe.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Verapamil Major
Clonidine Major
Ketoconazole Major
NSAIDs Moderate
Salbutamol Moderate
Insulin Moderate
Antacids Minor
Grapefruit juice Minor

🚨 Major Interactions

  • Verapamil or Diltiazem
  • Clonidine
  • CYP3A4 inhibitors (e.g., Ketoconazole, Itraconazole, Ritonavir)

⚡ Moderate Interactions

  • NSAIDs
  • Beta-2 agonists (e.g., Salbutamol)
  • Insulin and oral hypoglycemics

🍷 Alcohol Interaction

Alcohol may enhance the blood pressure-lowering effect of this medicine, leading to dizziness, fainting, or increased heart rate. It is advisable to avoid or limit alcohol consumption while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Severe bradycardia","Second or third-degree heart block","Cardiogenic shock","Decompensated heart failure","Severe peripheral arterial disease","Known hypersensitivity to Amlodipine or Atenolol","Untreated pheochromocytoma"]

⚠️ Warnings & Precautions

["Do not stop Atenolol abruptly; taper gradually to avoid angina or myocardial infarction.","Use with caution in patients with asthma or COPD; Atenolol may cause bronchospasm.","May mask symptoms of hypoglycemia in diabetics.","May worsen symptoms of peripheral arterial disease.","Use with caution in patients with hepatic impairment; Amlodipine dose may need adjustment.","Use with caution in renal impairment; Atenolol dose may need adjustment.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding."]

🤱 Lactation Safety

Amlodipine is present in breast milk in small amounts; Atenolol is also excreted in breast milk. Caution is advised. Consult your doctor before breastfeeding.

💊 Overdose Management

Overdose may cause severe hypotension, bradycardia, heart failure, and bronchospasm. Seek immediate medical attention. Treatment is supportive and symptomatic, including activated charcoal, IV fluids, vasopressors, and atropine for bradycardia. Hemodialysis may be considered for Atenolol removal.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not stop taking it suddenly, as abrupt withdrawal of Atenolol can worsen angina or cause a heart attack. Do not double the dose if you miss one. Avoid alcohol while taking this medicine, as it can increase dizziness and low blood pressure. Inform your doctor if you have asthma, diabetes, kidney or liver disease, or thyroid disorders. Regular monitoring of blood pressure, heart rate, and kidney function is important. Do not use this medicine during pregnancy unless clearly needed and advised by your doctor. Keep this medicine out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more sensitive to the effects of this medicine, especially dizziness, bradycardia, and low blood pressure. Start with lower doses and monitor closely. Regular assessment of renal function is advised.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before conceiving. This medicine may not be suitable during pregnancy. Your doctor may switch you to a safer alternative.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthesia and affect heart rate and blood pressure during surgery. Do not stop the medicine unless instructed.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine, as it may affect blood pressure and heart rate during dental procedures. Local anesthetics with epinephrine should be used with caution.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce strain on your heart.
🥗
Follow a low-sodium diet to help control blood pressure.
😴
Engage in regular physical activity as advised by your doctor.
💧
Avoid smoking and limit alcohol consumption.
🧘
Manage stress through relaxation techniques like deep breathing or meditation.
🌞
Get adequate sleep and maintain a regular sleep schedule.

🏋️ Exercise Considerations

This medicine may cause dizziness and fatigue, especially when starting treatment. Avoid strenuous exercise until you know how the medicine affects you. Stay hydrated during exercise. If you experience chest pain, shortness of breath, or severe dizziness during exercise, stop and seek medical attention.

🥗 Diet Recommendations

Reduce salt intake to less than 5 grams per day.
Include potassium-rich foods like bananas, oranges, and spinach (unless advised otherwise).
Limit saturated fats and cholesterol.
Eat plenty of fruits, vegetables, and whole grains.
Avoid excessive caffeine, which can increase heart rate.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or fatigue, especially when you first start taking it. Avoid driving or operating heavy machinery until you know how it affects you. It is usually safe to continue your normal daily activities, but listen to your body and rest if needed.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. Abrupt withdrawal of Atenolol can worsen angina or cause a heart attack. Your doctor may gradually reduce the dose if needed. If you experience serious side effects, contact your doctor immediately for advice.

📅 Long-Term Use Effects

Long-term use of this medicine is generally safe when monitored appropriately. Regular check-ups for blood pressure, heart rate, kidney function, and electrolytes are recommended. Atenolol may cause fatigue and reduced exercise tolerance. Amlodipine may cause persistent ankle swelling. Do not stop the medicine without medical advice.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet, exercise, and stress reduction can help lower blood pressure and complement medicine.

Evidence: Well-established
Other antihypertensive combinations

Your doctor may consider alternatives like ARBs, ACE inhibitors, or diuretics based on your condition.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. However, inform your healthcare provider about this medicine before receiving any vaccine. Continue routine vaccinations as recommended.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid loss. Store at room temperature and protect from extreme heat or moisture. If crossing time zones, consult your doctor about adjusting the timing of your dose. Ensure you have enough supply for your entire trip.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with a history of hypertension and angina
He was prescribed this medicine after his blood pressure remained high on a single drug. Within a few weeks, his blood pressure stabilized and angina episodes reduced. He experienced mild ankle swelling, which was managed by elevating his legs and reducing salt intake. He emphasized the importance of not missing doses.
💡 Lesson: Combination therapy can effectively control blood pressure and angina when a single drug is insufficient. Regular follow-up and lifestyle modifications are key.
👤 A 62-year-old woman with hypertension and diabetes
She started this medicine and noticed improved blood pressure control. However, she experienced episodes of dizziness when standing up quickly. Her doctor advised her to rise slowly and monitored her heart rate. She also learned that Atenolol can mask low blood sugar symptoms, so she checked her glucose more frequently.
💡 Lesson: Elderly patients and diabetics need careful monitoring for side effects like dizziness and masked hypoglycemia. Dose adjustments may be necessary.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts lowering blood pressure within a few hours, but full effect may take 1 to 2 weeks. Your doctor will monitor your response.

Q: Can I stop taking this medicine if I feel better?

A: No, you should not stop without consulting your doctor. High blood pressure often has no symptoms, and stopping suddenly can cause serious problems.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q: Is it safe to take this medicine during pregnancy?

A: Consult your doctor. This medicine is generally not recommended during pregnancy unless clearly needed. Your doctor will weigh the benefits and risks.

Q: Can I take this medicine with other blood pressure medicines?

A: Only if prescribed by your doctor. Combining with other blood pressure medicines can increase the risk of low blood pressure and other side effects.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my diabetes medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for amlowin at 5 mg/50 mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be stopped once blood pressure is normal.
    Fact: High blood pressure often requires long-term treatment. Stopping suddenly can cause rebound hypertension or angina.
  • Myth: This medicine causes kidney damage.
    Fact: When used as prescribed, it helps protect kidneys by controlling blood pressure. Regular monitoring is important.
  • Myth: You can take this medicine with alcohol without any issues.
    Fact: Alcohol can increase dizziness and low blood pressure. It is best to avoid or limit alcohol.

🔄 Alternative Options

Generic Alternatives

  • Amlodipine 5 mg + Atenolol 50 mg tablet (generic)

Brand Alternatives

  • Amlokem AT 5 mg/50 mg tablet

📊 Comparison with Similar Medicines

[{"medicine":"Amlodipine + Atenolol","class":"Calcium channel blocker + Beta-blocker","key_difference":"Combines vasodilation with heart rate reduction."},{"medicine":"Amlodipine + Metoprolol","class":"Calcium channel blocker + Beta-blocker","key_difference":"Metoprolol is more cardioselective and may have different side effect profile."},{"medicine":"Amlodipine + Hydrochlorothiazide","class":"Calcium channel blocker + Diuretic","key_difference":"Diuretic helps remove excess fluid, useful in edema."}]

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