Amiodar 100 Tablet: Complete Guide to Uses, Side Effects, and Safety
When to Call Your Doctor IMMEDIATELY
- New or worsening cough, shortness of breath, or chest pain
- Blurred vision or loss of vision
- Yellowing of the eyes or skin, dark urine, or severe abdominal pain
- Unusual fatigue, weight gain or loss, or neck swelling
- Fainting, near-fainting, or palpitations
- Numbness, tingling, or weakness in hands or feet
- Severe dizziness or slow heartbeat
- Signs of bleeding such as easy bruising, blood in stool, or vomiting blood
If experiencing severe symptoms, call emergency services immediately.
What is amiodar 100 tablet used for?
This medicine contains Amiodarone 100 mg, a powerful antiarrhythmic drug used to treat serious heart rhythm disorders such as ventricular tachycardia, ventricular fibrillation, and atrial fibrillation. It works by blocking multiple ion channels in the heart to stabilize its electrical activity. It requires regular monitoring of the heart, lungs, liver, thyroid, and eyes.
- Generic Name: Amiodarone
- Manufacturer: Micro Labs Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 amiodar 100 tablet के बारे में (Hindi Summary)
उपयोग: यह दवा अमियोडेरोन 100 मिलीग्राम टैबलेट है, जिसका उपयोग दिल की धड़कन की गंभीर समस्याओं जैसे वेंट्रिकुलर टैचीकार्डिया, वेंट्रिकुलर फाइब्रिलेशन, और एट्रियल फाइब्रिलेशन के इलाज और रोकथाम के लिए किया जाता है। यह दिल की मांसपेशियों में कई आयन चैनलों को ब्लॉक करके दिल की धड़कन को नियमित करने में मदद करती है। यह दवा केवल हृदय रोग विशेषज्ञ की देखरेख में ही लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में जी मिचलाना, कब्ज, थकान, चक्कर आना, और धूप से त्वचा में जलन शामिल हैं। लंबे समय तक उपयोग से त्वचा का रंग नीला-भूरा हो सकता है। गंभीर दुष्प्रभावों में फेफड़ों में सूजन, थायरॉइड की समस्या, लिवर की क्षति, आंखों की समस्या, और दिल की धड़कन में गड़बड़ी शामिल हैं। कोई भी नया लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें, अपने आप बंद न करें। धूप में जाने से बचें और सनस्क्रीन का उपयोग करें। अपने सभी डॉक्टरों को बताएं कि आप यह दवा ले रहे हैं, क्योंकि यह कई दवाओं के साथ प्रतिक्रिया करती है। नियमित रूप से रक्त परीक्षण, आंखों की जांच, और थायरॉइड की जांच करवाते रहें। गर्भवती महिलाओं को यह दवा नहीं लेनी चाहिए। अंगूर का जूस न पिएं।
💊 amiodar 100 tablet Uses & Benefits
[{"condition":"Ventricular tachycardia","description":"This medicine is used to suppress and prevent recurrent episodes of ventricular tachycardia, a potentially life-threatening fast heart rhythm that starts in the lower chambers of the heart.","evidence":"Well-established"},{"condition":"Ventricular fibrillation","description":"This medicine is used to reduce the risk of recurrent ventricular fibrillation, a chaotic heart rhythm that can cause sudden cardiac arrest.","evidence":"Well-established"},{"condition":"Atrial fibrillation","description":"This medicine helps maintain normal sinus rhythm in patients with atrial fibrillation, especially when other antiarrhythmic drugs are ineffective or not tolerated.","evidence":"Well-established"},{"condition":"Atrial flutter","description":"This medicine is used to control and prevent atrial flutter, a rapid but regular abnormal heart rhythm originating in the upper chambers.","evidence":"Well-established"},{"condition":"Supraventricular tachycardia","description":"This medicine may be used in selected patients with difficult-to-control supraventricular tachycardia when other treatments fail.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Refractory ventricular arrhythmias in heart failure","description":"Sometimes used off-label in patients with heart failure and implanted defibrillators who continue to have shocks despite standard therapy.","evidence":"Limited"},{"condition":"Arrhythmias in hypertrophic cardiomyopathy","description":"May be prescribed off-label to manage atrial fibrillation or ventricular arrhythmias in patients with hypertrophic cardiomyopathy.","evidence":"Limited"}]
Primary treatment for: Ventricular arrhythmias
Also treats: Atrial fibrillation, Atrial flutter, Supraventricular tachycardia
📋 Drug Information
| Generic Name(s) | Amiodarone |
| Brand Name | Amiodar 200 Tablet |
| Manufacturer | Micro Labs Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Class III Agents- anti arrhythmic |
| Route of Administration | Oral |
| Storage | Store this medicine at room temperature between 15°C and 30°C (59°F to 86°F). Keep it in the original container, tightly closed, away from moisture, heat, and direct light. Do not store it in the bathroom. Keep out of reach of children and pets. |
| Shelf Life | The shelf life of this medicine is typically 24 months from the date of manufacture, but refer to the expiry date printed on the pack. Do not use after the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by blocking multiple ion channels in heart muscle cells. It blocks potassium channels, which prolongs the cardiac action potential and the refractory period, helping to stop abnormal re-entrant circuits. It also blocks sodium channels, which slows electrical conduction, and calcium channels, which reduces the automaticity of the heart's pacemaker cells. In addition, it has weak beta-blocking and alpha-blocking effects. Together, these actions stabilize the heart's electrical activity and suppress dangerous arrhythmias.
Mechanism Steps
💡 How to Take amiodar 100 tablet
Strength: Amiodarone 100 mg immediate-release tablet for oral administration.
Dosage Information
| Adult Dosage | The dose of this medicine must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function, and response to treatment. For oral Amiodarone, a common loading regimen is 800 to 1600 mg daily in divided doses for 1 to 3 weeks, followed by a maintenance dose of 200 to 400 mg daily. However, this 100 mg tablet allows finer dose adjustments. Do not adjust the dose without your doctor's guidance. |
| Pediatric Dosage | Pediatric dosing of Amiodarone is not established from available information for this 100 mg tablet. Consult a pediatric cardiologist for appropriate dosing in children. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of Amiodarone, especially bradycardia, thyroid dysfunction, and lung toxicity. Doses should be started at the lower end of the range and adjusted carefully based on response and monitoring. Regular check-ups are especially important in this age group. |
| Renal Impairment | Amiodarone is primarily metabolized by the liver and excreted in bile, so renal impairment generally does not require dose adjustment. However, kidney function should be monitored, especially if other kidney-toxic drugs are used. |
| Hepatic Impairment | Amiodarone is extensively metabolized in the liver. In patients with severe liver disease, the dose may need to be reduced, and liver function should be monitored closely. Use with caution in patients with hepatic impairment. |
| Maximum Daily Dose | The maximum daily dose of Amiodarone for oral maintenance is generally 400 mg, but higher loading doses may be used for short periods under close medical supervision. The exact maximum dose must be determined by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of amiodar 100 tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Digoxin | Major | |
| Simvastatin | Major | |
| Beta-blockers | Major | |
| Verapamil | Major | |
| Diltiazem | Major | |
| Sotalol | Major | |
| Quinidine | Major | |
| Phenytoin | Moderate | |
| Cyclosporine | Moderate |
🚨 Major Interactions
- Warfarin
- Digoxin
- Beta-blockers
- Calcium channel blockers (verapamil, diltiazem)
- Simvastatin
- QT-prolonging drugs (e.g., sotalol, quinidine, macrolide antibiotics, antipsychotics)
⚡ Moderate Interactions
- Phenytoin
- Cyclosporine
- Fentanyl
- Lidocaine
- Methotrexate
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Alcohol can worsen dizziness, low blood pressure, and liver stress, and it may increase the risk of abnormal heart rhythms. If you drink alcohol regularly, discuss it with your doctor before starting this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Severe sinus node dysfunction or sinoatrial heart block without a pacemaker","Second- or third-degree atrioventricular block without a pacemaker","Cardiogenic shock","Severe hypotension","Known hypersensitivity to Amiodarone or iodine","Thyroid dysfunction (hypothyroidism or hyperthyroidism) unless controlled","Pre-existing pulmonary fibrosis or interstitial lung disease","Severe liver disease","Pregnancy unless life-threatening arrhythmia and no alternative"]
⚠️ Warnings & Precautions
["This medicine can cause serious lung, thyroid, liver, eye, and nerve toxicity. Regular monitoring is essential.","Do not stop this medicine suddenly without your doctor's advice, as it can trigger dangerous heart rhythms.","Avoid prolonged sun exposure and use sunscreen, because this medicine can cause severe photosensitivity.","Tell all healthcare providers that you are taking this medicine, as it interacts with many drugs.","Use effective contraception if you are a woman of childbearing age.","Avoid grapefruit juice while taking this medicine.","Report any new cough, shortness of breath, vision changes, or unusual fatigue to your doctor promptly.","This medicine may impair your ability to drive or operate machinery, especially when starting treatment."]
🤱 Lactation Safety
Amiodarone is excreted in breast milk in significant amounts and can accumulate in the nursing infant because of its long half-life. Breastfeeding is not recommended while taking this medicine. If treatment is essential, alternative infant feeding should be discussed with your doctor.
💊 Overdose Management
Overdose of this medicine can cause severe bradycardia, heart block, hypotension, and cardiac arrest. There is no specific antidote. Treatment is supportive and may include intravenous fluids, vasopressors, and temporary cardiac pacing. Because of the long half-life, effects may persist for a long time. If overdose is suspected, seek emergency medical care immediately.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember if less than half the dosing interval has passed. If more than half the interval has passed, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are unsure, contact your doctor or pharmacist.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor, at the same time each day, with or without food. Do not stop this medicine suddenly on your own, because stopping abruptly can trigger dangerous heart rhythms. Avoid prolonged sun exposure and use sunscreen, because this medicine can make your skin very sensitive to sunlight. Tell every doctor, dentist, or pharmacist you visit that you are taking this medicine, since it interacts with many common drugs including blood thinners, cholesterol medicines, and certain antibiotics. Keep all scheduled blood tests, eye examinations, chest X-rays, and thyroid checks. Use a reliable method of birth control if you are a woman of childbearing age, because this medicine can harm an unborn baby. Do not drink grapefruit juice while taking this medicine, as it can raise the drug level in your blood. Store the tablets at room temperature, away from moisture and direct light, and keep them out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more prone to side effects such as bradycardia, thyroid dysfunction, and lung toxicity. Lower starting doses and more frequent monitoring are recommended. Falls due to dizziness or slow heart rate are a concern; take precautions to prevent falls.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy or when planning pregnancy. It can harm the unborn baby, especially the thyroid. Women of childbearing age should use effective contraception. If you are planning pregnancy, consult your doctor well in advance to discuss alternative treatments.
🏥 Post-Surgery Considerations
After surgery, inform your surgical team that you are taking this medicine. It can interact with anesthetic agents and affect heart rhythm. Your doctor may need to monitor your heart rhythm and adjust other medications during the perioperative period.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. It can interact with certain local anesthetics and antibiotics. Your dentist may need to consult your cardiologist before prescribing any new medicines.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine can cause dizziness, fatigue, and slow heart rate, which may affect your ability to exercise. Avoid strenuous exercise until you know how the medicine affects you. Consult your doctor before starting any new exercise program. If you experience chest pain, shortness of breath, or severe dizziness during exercise, stop immediately and seek medical attention.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, fatigue, and vision changes, which can affect your ability to drive or operate machinery. Avoid driving until you know how it affects you. It may also require frequent medical appointments for monitoring, which can impact your work schedule. Discuss any work-related concerns with your doctor.
🛑 When to Stop This Medicine
Do not stop this medicine without your doctor's advice. Your doctor may decide to stop or change the medicine based on your response, side effects, or if your heart rhythm normalizes. If you experience serious side effects, contact your doctor immediately; they will decide whether to stop the medicine or adjust the dose.
📅 Long-Term Use Effects
Long-term use of this medicine can lead to accumulation in body tissues and cause thyroid dysfunction, lung toxicity, liver injury, eye problems, and skin discoloration. Regular monitoring of thyroid, liver, lung, and eye health is essential. The dose may need to be adjusted over time based on these tests and your response. Some side effects may be irreversible if not detected early.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
A procedure that can cure certain arrhythmias by destroying abnormal heart tissue.
Evidence: Well-established for many arrhythmiasA device that monitors heart rhythm and delivers a shock if a dangerous arrhythmia occurs.
Evidence: Well-established for preventing sudden cardiac deathReducing caffeine, alcohol, and stress can help manage some arrhythmias.
Evidence: Supportive💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions with this medicine. However, because it can affect the immune system and liver, discuss the timing of any vaccinations with your doctor. Annual influenza vaccination is generally recommended for patients with heart disease.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss or temperature extremes. If crossing time zones, consult your doctor about adjusting the timing of doses. Store it at room temperature and avoid leaving it in a hot car. Check customs regulations for carrying prescription medicines to your destination. Always carry enough supply for the entire trip plus extra in case of delays.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine may take several days to weeks to achieve its full effect, depending on the loading dose and individual response. Your doctor will monitor your heart rhythm regularly.
A: No, you should never stop this medicine suddenly without your doctor's advice. Stopping abruptly can trigger dangerous heart rhythms.
A: If you miss a dose, take it as soon as you remember if less than half the dosing interval has passed. If more than half has passed, skip it and continue with your regular schedule. Do not double dose.
A: Yes, this medicine can affect thyroid function. Regular thyroid tests are recommended. Report any unexplained weight change, fatigue, or neck swelling to your doctor.
A: Yes, you can take it with or without food, but taking it with food may reduce stomach upset. Avoid grapefruit juice.
🤔 Common Patient Concerns
🔄 Substitutes for amiodar 100 tablet
View AllAlternative brands with exact same active ingredient:
-
Panarone 100mg TabletPanacea Biotec Ltd ₹24.49 62.7% CHEAPER
-
panarol 100mg tabletKhandelwal Laboratories Pvt Ltd ₹31.55 51.9% CHEAPER
-
amiojust 100mg tabletRidhima Biocare ₹51.56 21.4% CHEAPER
-
amiodon 100mg tabletNeon Laboratories Ltd ₹52.03 20.7% CHEAPER
-
eurythmic 100mg tabletTroikaa Pharmaceuticals Ltd ₹54.38 17.1% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Amiodarone is a safe drug with no serious side effects.
Fact: Amiodarone can cause serious lung, liver, thyroid, eye, and nerve toxicity. Regular monitoring is essential. - Myth: You can stop Amiodarone as soon as you feel better.
Fact: Stopping Amiodarone suddenly can trigger dangerous heart rhythms. Always consult your doctor before stopping. - Myth: Amiodarone is safe to take during pregnancy.
Fact: Amiodarone can harm the unborn baby, especially the thyroid. It is not recommended during pregnancy unless absolutely necessary. - Myth: Amiodarone does not interact with other medicines.
Fact: Amiodarone interacts with many drugs, including warfarin, digoxin, and statins. Always inform your doctor about all medicines you take.
🔄 Alternative Options
Generic Alternatives
- Amiodarone 100 mg tablet
Brand Alternatives
- Amiodar 100 Tablet