amexil lotion - Uses, Price, Side Effects & Substitutes
What is amexil lotion used for?
Ascabiol Emulsion (Lindane + Cetrimide) is used to treat DERMA. It contains Lindane (1% w/v) + Cetrimide (0.1% w/v), which Lindane is a neurotoxin that disrupts GABA-gated chloride channels in parasites,. Always consult your doctor before use. Take as prescribed.
- Generic Name: Lindane + Cetrimide
- Manufacturer: Lanark Laboratories Pvt Ltd
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ amexil lotion Uses & Benefits
Treatment of scabies and pediculosis (lice infestations).
Off-label uses: None commonly recognized.
๐ Drug Information
| Generic Name(s) | Lindane + Cetrimide |
| Brand Name | Ascabiol Emulsion |
| Manufacturer | Lanark Laboratories Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | Scabicide and Pediculicide |
| Route of Administration | Topical |
| Storage | Store at room temperature (20-25ยฐC); protect from light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Lindane is a neurotoxin that disrupts GABA-gated chloride channels in parasites, causing hyperexcitation and death. Cetrimide is a detergent that disrupts cell membranes.
Mechanism Steps
๐ก How to Take amexil lotion
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of amexil lotion
โ Common Side Effects
- Skin irritation
- Pruritus
- Burning sensation
- Dryness
๐จ Serious Side Effects
- Seizures
- Dizziness
- Ataxia
- Arrhythmias
โ ๏ธ Rare Side Effects
- Aplastic anemia
- Hepatotoxicity
- Allergic dermatitis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| CYP3A4 Inducers | Major | May increase lindane metabolism and reduce efficacy. |
| CYP3A4 Inhibitors | Major | May decrease lindane metabolism and increase toxicity. |
| Other Neurotoxic Drugs | Major | Additive neurotoxicity risk. |
๐จ Major Interactions
- CYP3A4 inducers
- CYP3A4 inhibitors
- Other neurotoxic drugs
โก Moderate Interactions
- Topical corticosteroids
- Other topical medications
โน๏ธ Minor Interactions
- None significant
๐ฝ๏ธ Food Interactions
None known.
๐ท Alcohol Interaction
No known interaction.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to lindane or cetrimide; premature infants; patients with seizure disorders; broken or inflamed skin.
๐ Monitoring Parameters
Observe for skin irritation, neurological symptoms (dizziness, seizures), and treatment efficacy.
๐คฑ Lactation Safety
Avoid use; lindane may be excreted in breast milk.
๐ Overdose Management
Remove product by washing; symptomatic and supportive care; anticonvulsants for seizures.
โฐ Missed Dose
Apply as soon as remembered; do not double dose.