alzap im 6mg/400mg tablet - Ivermectin (6mg) + Albendazole (400mg) medicine

ABD Plus Tablet: Comprehensive Guide to Uses, Side Effects, and Safety

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🏭 Dokcare Life Sciences 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 24, 2026
⚠️ Hepatotoxicity Risk 🤰 Pregnancy Category Not established from the available information. However, both ivermectin and albendazole are generally avoided during pregnancy, especially in the first trimester, unless the potential benefit justifies the potential risk. Consult your doctor. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate to well-established for individual components; combination evidence is limited.
Reviewed by
SaathiMed Expert Panel | Sep 24, 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Unusual bruising or bleeding
  • Seizures or confusion

If experiencing severe symptoms, call emergency services immediately.

What is alzap im 6mg/400mg tablet used for?

This medicine is a combination of Ivermectin 6 mg and Albendazole 400 mg used to treat mixed parasitic infections. It works by paralysing and killing worms, which are then expelled from the body. It is taken orally with food, usually as a single dose or repeated as prescribed.

  • Generic Name: Ivermectin + Albendazole
  • Manufacturer: Dokcare Life Sciences
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 alzap im 6mg/400mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा इवरमेक्टिन 6 मिलीग्राम और अल्बेंडाजोल 400 मिलीग्राम का संयोजन है, जिसका उपयोग विभिन्न प्रकार के परजीवी संक्रमणों के इलाज के लिए किया जाता है। यह पेट के कीड़ों, स्केबीज, और फाइलेरिया जैसे संक्रमणों में प्रभावी है। यह दवा कीड़ों को लकवा मारकर मार देती है, जिसके बाद वे शरीर से बाहर निकल जाते हैं। इसे भोजन के साथ मुँह से लिया जाता है। डॉक्टर के परामर्श के बिना इसका सेवन न करें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, दस्त, सिरदर्द, चक्कर आना और थकान शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। कुछ लोगों में फाइलेरिया के इलाज के दौरान बुखार, खुजली, दाने और मांसपेशियों में दर्द हो सकता है, जिसे माज़ोटी प्रतिक्रिया कहते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको आंखों या त्वचा का पीलापन, गहरे रंग का मूत्र, या गंभीर पेट दर्द हो, तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे भोजन के साथ लें ताकि पेट की परेशानी कम हो। इस दवा के सेवन के दौरान शराब न पिएं। यदि आप गर्भवती हैं, गर्भवती होने की योजना बना रही हैं, या स्तनपान करा रही हैं, तो अपने डॉक्टर को बताएं। इस दवा को गर्भावस्था में न लें। स्तनपान कराने वाली महिलाएं अंतिम खुराक के बाद कम से कम एक सप्ताह तक स्तनपान न कराएं। चक्कर या नींद आने पर वाहन न चलाएं। पूरा कोर्स पूरा करें। दवा को ठंडी, सूखी जगह पर रखें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 alzap im 6mg/400mg tablet Uses & Benefits

[{"condition":"Mixed intestinal parasitic infections","description":"Used to treat infections caused by multiple intestinal worms such as roundworm, hookworm, whipworm, and threadworm when both ivermectin and albendazole are indicated.","evidence":"Well-established"},{"condition":"Strongyloidiasis","description":"Ivermectin is the drug of choice for Strongyloides stercoralis; albendazole provides additional coverage against other worms.","evidence":"Well-established"},{"condition":"Scabies","description":"Ivermectin is effective against scabies mites, and albendazole may help with concurrent intestinal parasites.","evidence":"Well-established"},{"condition":"Filariasis","description":"Used in mass drug administration for lymphatic filariasis in some regions, though albendazole is often combined with diethylcarbamazine or ivermectin alone.","evidence":"Established"},{"condition":"Cutaneous larva migrans","description":"Albendazole and ivermectin are both effective against creeping eruption caused by hookworm larvae.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Rosacea","description":"Topical ivermectin is approved for rosacea, but oral ivermectin is not standard; combination with albendazole is not established.","evidence":"Limited"},{"condition":"Head lice","description":"Oral ivermectin has been used off-label for resistant head lice, but albendazole is not typically included.","evidence":"Limited"}]

Primary treatment for: Parasitic infections

Also treats: Strongyloidiasis, Scabies, Filariasis, Cutaneous larva migrans

📋 Drug Information

Generic Name(s)Ivermectin + Albendazole
Brand NameABD Plus Tablet
ManufacturerDokcare Life Sciences
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassAnthelmintics
Route of AdministrationOral
StorageStore below 30°C in a cool, dry place, protected from light and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information. For specific parasitic infections, refer to WHO guidelines for ivermectin and albendazole use.
ICMR GuidelineNot established from the available information. Consult ICMR guidelines for parasitic infections.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with a fatty meal to enhance the absorption of albendazole.
2
Complete the full course as prescribed, even if symptoms improve, to prevent reinfection and resistance.
3
Avoid alcohol during treatment to reduce the risk of liver toxicity.
4
Inform your doctor if you are taking blood thinners, as this medicine can increase bleeding risk.
5
Do not use this medicine for viral infections like COVID-19; it is not effective.
6
If you experience dizziness or drowsiness, avoid driving or operating heavy machinery.
7
Report any signs of liver problems, such as yellowing of eyes or skin, immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Itching and rash
This medicine is used for scabies and other parasitic skin infections.
Likely Use
Abdominal pain and worms in stool
This medicine treats intestinal worms.
Likely Use
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionIvermectin is well absorbed from the gastrointestinal tract, with peak plasma levels reached in about 4 hours. Albendazole is poorly absorbed but absorption increases when taken with a fatty meal; its active metabolite, albendazole sulfoxide, reaches peak levels in 2–5 hours.
DistributionIvermectin is highly lipophilic and distributes widely into tissues, including fat, liver, and skin. Albendazole and its metabolites are distributed to various tissues, including liver, lungs, and muscles, but penetration into cerebrospinal fluid is limited unless inflammation is present.
Protein BindingIvermectin is about 93% bound to plasma proteins. Albendazole is about 70% bound to plasma proteins.
MetabolismIvermectin is primarily metabolised in the liver by CYP3A4. Albendazole undergoes extensive first-pass metabolism in the liver to its active metabolite, albendazole sulfoxide, via CYP3A4 and flavin-containing monooxygenases.
Half-LifeIvermectin half-life is approximately 18 hours. Albendazole sulfoxide half-life is about 8–12 hours.
ExcretionIvermectin is mainly excreted in faeces, with less than 1% excreted unchanged in urine. Albendazole metabolites are excreted mainly in urine and bile.
BioavailabilityIvermectin oral bioavailability is about 60% but can vary. Albendazole bioavailability is low, about 5%, but increases significantly when taken with a fatty meal.
Onset of ActionParasite paralysis begins within hours, but clinical improvement may take days to weeks depending on the infection.
Peak Plasma TimeIvermectin: about 4 hours; Albendazole sulfoxide: 2–5 hours.
Duration of ActionThe antiparasitic effect persists for several days after a single dose, but repeated dosing may be needed for certain infections.

How It Works

This medicine combines two antiparasitic agents with complementary mechanisms. Ivermectin binds to glutamate-gated chloride channels in invertebrate nerve and muscle cells, causing hyperpolarisation and paralysis of the parasite. Albendazole binds to beta-tubulin, inhibiting microtubule polymerisation, which disrupts glucose uptake and leads to energy depletion and death of the worm. Together, they provide broad-spectrum activity against many nematodes, cestodes, and some ectoparasites.

Mechanism Steps

1
Ivermectin binding: Ivermectin binds to glutamate-gated chloride channels on parasite nerve and muscle cells, increasing chloride ion influx.
2
Paralysis of parasite: The increased chloride influx hyperpolarises the cell membrane, leading to paralysis and eventual death of the parasite.
3
Albendazole binding: Albendazole binds to beta-tubulin, preventing microtubule assembly.
4
Energy depletion: Disruption of microtubules impairs glucose uptake and other cellular functions, causing energy depletion and death of the worm.
5
Expulsion: Paralysed and dead worms are expelled from the body through normal bowel movements.

💡 How to Take alzap im 6mg/400mg tablet

Strength: Each tablet contains Ivermectin 6 mg and Albendazole 400 mg.

1Take the tablet with a full glass of water.
2Take it with food to improve absorption and reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Follow the prescribed schedule exactly.
5Do not skip doses or stop early without consulting your doctor.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one tablet (Ivermectin 6 mg + Albendazole 400 mg) taken orally once daily with food. The duration of treatment depends on the type of infection: for intestinal worms, a single dose may be sufficient; for strongyloidiasis, it may be repeated after 1–2 weeks; for scabies, a single dose may be repeated after 1–2 weeks. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician. This medicine is generally not recommended for children under 2 years or weighing less than 15 kg.
Elderly DosageElderly patients may have reduced liver or kidney function; dose adjustment may be necessary. Consult a doctor for individualized dosing.
Renal ImpairmentNo specific dose adjustment is established for renal impairment. Use with caution and monitor renal function. Consult a doctor.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Dose adjustment may be needed based on liver function tests. Consult a doctor.
Maximum Daily DoseThe maximum recommended daily dose is one tablet (Ivermectin 6 mg + Albendazole 400 mg). Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Increases absorption of albendazole and reduces stomach upset.
Grapefruit
Avoid
May increase ivermectin levels and risk of side effects.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of alzap im 6mg/400mg tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. If it persists, consult your doctor.
Abdominal pain (Common (5-10%))
Usually temporary. Try taking with a meal. If severe, contact your doctor.
Headache (Common (5-10%))
Rest and stay hydrated. Consult doctor if headache is severe or persistent.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you feel normal.
Fatigue (Common (5-10%))
Get adequate rest. If fatigue interferes with daily activities, consult your doctor.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of face, lips, tongue, or throat, difficulty breathing, or a severe rash.
Liver toxicity (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe abdominal pain immediately.
Bone marrow suppression (Rare (<0.1%))
Report unusual bruising, bleeding, or signs of infection such as fever and sore throat.
Seizures (Very rare (<0.01%))
Seek emergency medical help if seizures occur.

⚠️ Rare Side Effects

Prolonged QT interval
Report palpitations or fainting to your doctor.
Stevens-Johnson syndrome
Seek immediate medical attention if you develop a painful rash with blisters or peeling skin.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Ketoconazole Major
Rifampicin Major
Dexamethasone Moderate
Praziquantel Moderate
Grapefruit juice Minor

🚨 Major Interactions

  • Warfarin
  • CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
  • CYP3A4 inducers (e.g., rifampicin, carbamazepine)

⚡ Moderate Interactions

  • Dexamethasone
  • Praziquantel

🍷 Alcohol Interaction

Alcohol should be avoided while taking this medicine because both ivermectin and albendazole are metabolised by the liver, and alcohol can increase the risk of liver toxicity. Alcohol may also worsen side effects such as dizziness and drowsiness.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to ivermectin, albendazole, or any component of the formulation.","Pregnancy, especially in the first trimester, unless clearly needed.","Breastfeeding during treatment and for one week after the last dose.","Children under 2 years of age or weighing less than 15 kg (unless directed by a doctor).","Concurrent use with drugs that strongly inhibit or induce CYP3A4 should be avoided or monitored."]

⚠️ Warnings & Precautions

["Use with caution in patients with liver disease; monitor liver enzymes.","Use with caution in patients with kidney disease; dose adjustment may be needed.","Avoid alcohol during treatment.","May cause dizziness or drowsiness; avoid driving or operating machinery until you know how it affects you.","Do not use for viral infections such as COVID-19; it is not effective.","Complete the full course as prescribed to prevent resistance.","Inform your doctor if you are taking blood thinners or anticonvulsants."]

🤱 Lactation Safety

Ivermectin and albendazole are excreted in breast milk. Breastfeeding should be avoided for at least one week after the last dose. Consult your doctor for guidance.

💊 Overdose Management

Overdose may cause nausea, vomiting, diarrhoea, dizziness, and in severe cases, seizures, coma, and respiratory depression. There is no specific antidote. Treatment is supportive and symptomatic. Seek immediate medical attention if overdose is suspected.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not self-medicate or share it with others. Swallow the tablet whole with a glass of water. It is best taken with food to reduce stomach upset. Avoid alcohol while taking this medicine as it may increase the risk of liver problems. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. This medicine is not recommended during pregnancy, especially in the first trimester, and breastfeeding should be avoided for at least one week after the last dose. Tell your doctor about all other medicines you are taking, especially blood thinners, anticonvulsants, and drugs that affect liver enzymes. Do not drive or operate heavy machinery if you feel dizzy or drowsy after taking this medicine. Complete the full course even if you feel better after a few doses. Store the tablets in a cool, dry place away from direct sunlight and out of reach of children. If you miss a dose, take it as soon as you remember, but if it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have reduced liver and kidney function, increasing the risk of side effects. Dose adjustment may be necessary. Monitor liver and kidney function during treatment.

🤰 Pregnancy Planning (TTC)

This medicine is not recommended during pregnancy, especially in the first trimester. If you are planning pregnancy, consult your doctor before taking this medicine. Use effective contraception during treatment and for at least one week after the last dose.

🏥 Post-Surgery Considerations

There are no specific restrictions, but inform your surgeon if you are taking this medicine. It may interact with other medications used during surgery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may interact with medications used during dental procedures. No specific precautions are otherwise required.

💚 Lifestyle Tips for Better Results

🏃
Maintain good personal hygiene, including regular handwashing and nail trimming.
🥗
Wash fruits and vegetables thoroughly before consumption.
😴
Avoid walking barefoot in areas where hookworm is common.
💧
Wash bedding and clothing in hot water if you have scabies.
🧘
Keep your environment clean to prevent reinfection.

🏋️ Exercise Considerations

If you experience dizziness or fatigue after taking this medicine, avoid strenuous exercise until you feel normal. Otherwise, light to moderate exercise is generally safe.

🥗 Diet Recommendations

Take the medicine with a meal containing some fat to enhance absorption.
Stay well hydrated.
Avoid alcohol.
Eat a balanced diet to support recovery.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. Otherwise, it usually does not significantly impact daily activities.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. Complete the full course as prescribed. If you experience severe side effects, contact your doctor immediately.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended unless prescribed for specific chronic infections. Prolonged use may increase the risk of liver toxicity and bone marrow suppression. Regular monitoring of liver function and blood counts is advised for extended therapy. Consult your doctor for periodic evaluations.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Albendazole alone

May be sufficient for intestinal worms but does not cover scabies or strongyloidiasis.

Evidence: Well-established
Ivermectin alone

Effective for scabies and strongyloidiasis but lacks broad intestinal worm coverage.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, consult your doctor for specific advice.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it in a cool, dry place, away from direct sunlight. If crossing time zones, continue taking the medicine at the same intervals as prescribed; consult your doctor for specific advice. Check customs regulations for carrying prescription medicines. Always carry enough supply for your entire trip.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with itching and rash diagnosed with scabies
He was prescribed this medicine as a single dose, repeated after one week. He also applied topical scabicide. His itching improved significantly within two weeks. He experienced mild nausea after the first dose but it resolved.
💡 Lesson: Taking the medicine with food and completing the repeat dose as prescribed is important for curing scabies.
👤 A 50-year-old woman with chronic abdominal discomfort and weight loss
Stool tests revealed mixed intestinal worms. She was given this medicine once daily for three days. Her symptoms resolved, and repeat stool tests were negative. She was advised to maintain good hygiene.
💡 Lesson: Proper diagnosis and completing the full course are essential for eradicating parasitic infections.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: The medicine starts acting within hours, but symptom relief may take a few days to weeks depending on the infection.

Q: Can I take this medicine without food?

A: It is best taken with food to improve absorption and reduce stomach upset.

Q: Is this medicine safe for children?

A: It is generally not recommended for children under 2 years or weighing less than 15 kg. Consult a pediatrician.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🛑 Myths vs. Facts

  • Myth: This medicine can cure COVID-19.
    Fact: There is no reliable evidence that ivermectin or albendazole are effective against COVID-19. They should not be used for this purpose.
  • Myth: This medicine is a general deworming tablet for everyone.
    Fact: It is a prescription medicine and should only be used for specific parasitic infections diagnosed by a doctor.

🔄 Alternative Options

Generic Alternatives

  • Ivermectin 6 mg + Albendazole 400 mg tablets from other manufacturers

Brand Alternatives

  • Not established from the available information.

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Ivermectin 6 mg + Albendazole 400 mg","uses":"Mixed parasitic infections","notes":"Combination for broad coverage"},{"medicine":"Albendazole alone","composition":"Albendazole 400 mg","uses":"Intestinal worms","notes":"Does not cover scabies or strongyloidiasis as effectively"},{"medicine":"Ivermectin alone","composition":"Ivermectin 6 mg","uses":"Strongyloidiasis, scabies, filariasis","notes":"Does not cover many intestinal worms"}]

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