Almero-S 1.5gm Injection: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Swelling of the face, lips, or throat, or difficulty breathing
- Sudden severe rash with blistering or peeling skin
- Seizures, confusion, or unusual movements
- Severe or bloody diarrhea, or diarrhea with fever and abdominal pain
- Unusual bruising, bleeding gums, or blood in urine or stool
- Decreased urine output or swelling in the legs
- Yellowing of the eyes or skin, or dark urine
- Chest pain, fainting, or a rapid heartbeat
If experiencing severe symptoms, call emergency services immediately.
What is almero-s 1.5gm injection used for?
This medicine is a prescription-only intravenous antibiotic that combines meropenem and sulbactam. It is used in hospitals to treat serious bacterial infections such as complicated abdominal infections, urinary tract infections, skin infections, and pneumonia. It works by killing bacteria and blocking the enzymes that make bacteria resistant. It must be given by a healthcare professional and is not for viral infections.
- Generic Name: Meropenem + Sulbactam
- Manufacturer: Vistica Life Sciences
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 almero-s 1.5gm injection के बारे में (Hindi Summary)
उपयोग: यह दवा मेरोपेनम और सल्बैक्टम का संयोजन है और इसे नस के माध्यम से दिया जाता है। यह अस्पताल में गंभीर बैक्टीरियल संक्रमणों के इलाज के लिए उपयोग की जाती है, जैसे पेट के अंदर के संक्रमण, मूत्र मार्ग के जटिल संक्रमण, त्वचा और मांसपेशियों के संक्रमण, और निमोनिया। यह दवा बैक्टीरिया को मारती है और उन एंजाइमों को रोकती है जो बैक्टीरिया को दवा के प्रति प्रतिरोधी बनाते हैं। यह वायरल बुखार या सर्दी-जुकाम के लिए नहीं है। इस दवा का उपयोग केवल डॉक्टर की देखरेख में किया जाना चाहिए और पूरा कोर्स पूरा करना जरूरी है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में दस्त, जी मिचलाना, उल्टी, सिरदर्द, चकत्ते और इंजेक्शन की जगह पर दर्द या सूजन शामिल हैं। गंभीर दुष्प्रभावों में एलर्जी की तीव्र प्रतिक्रिया, सांस लेने में कठिनाई, चेहरे या गले में सूजन, दौरे पड़ना, गंभीर दस्त, और खून की बीमारियां शामिल हो सकती हैं। अगर आपको इनमें से कोई भी लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह दवा केवल डॉक्टर या नर्स द्वारा नस के माध्यम से दी जाती है। इसे घर पर खुद से न लगाएं। अपने डॉक्टर को अपनी सभी एलर्जी, गुर्दे की बीमारी, लीवर की बीमारी, और दौरे की history के बारे में बताएं। डॉक्टर के बताए अनुसार पूरा कोर्स पूरा करें, चाहे आप बेहतर महसूस करने लगें। इलाज के दौरान शराब न पिएं। अगर दस्त, चकत्ते, सूजन या सांस लेने में तकलीफ हो तो तुरंत डॉक्टर को बताएं।
💊 almero-s 1.5gm injection Uses & Benefits
[{"condition":"Complicated intra-abdominal infections","description":"This medicine is used to treat serious abdominal infections such as perforated appendicitis, peritonitis, and intra-abdominal abscesses caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Complicated urinary tract infections","description":"It is prescribed for severe kidney and urinary tract infections, including pyelonephritis, that require intravenous antibiotic therapy.","evidence":"Well-established"},{"condition":"Complicated skin and soft tissue infections","description":"This medicine treats deep skin infections, infected wounds, and abscesses caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Community-acquired pneumonia","description":"It may be used for severe community-acquired pneumonia when resistant or mixed bacteria are suspected and intravenous therapy is needed.","evidence":"Well-established"},{"condition":"Hospital-acquired and ventilator-associated pneumonia","description":"This medicine is used for serious lung infections that develop during hospitalization or while on a breathing machine.","evidence":"Well-established"},{"condition":"Febrile neutropenia","description":"It is used as empiric therapy for fever in patients with low white blood cell counts, often after chemotherapy.","evidence":"Well-established"},{"condition":"Bacterial meningitis","description":"This medicine may be used for meningitis caused by susceptible bacteria because it penetrates the cerebrospinal fluid when the meninges are inflamed.","evidence":"Well-established"},{"condition":"Polymicrobial infections","description":"The combination of meropenem and sulbactam may be used when multiple types of bacteria, including beta-lactamase-producing strains, are likely.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Acinetobacter baumannii infections","description":"Sulbactam-containing regimens have been studied for multidrug-resistant Acinetobacter infections, but this is not a standard approved use for all formulations.","evidence":"Limited"},{"condition":"Stenotrophomonas maltophilia infections","description":"Some clinicians may use this combination when standard options are not suitable, but evidence is limited and susceptibility testing is essential.","evidence":"Limited"}]
Primary treatment for: Serious bacterial infections caused by susceptible organisms
Also treats: Complicated intra-abdominal infections, Complicated urinary tract infections, Complicated skin and soft tissue infections, Hospital-acquired pneumonia, Ventilator-associated pneumonia, Febrile neutropenia, Bacterial meningitis
📋 Drug Information
| Generic Name(s) | Meropenem + Sulbactam |
| Brand Name | Almero-S 1.5gm Injection |
| Manufacturer | Vistica Life Sciences |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Carbapenem antibiotic + Beta-lactamase inhibitor |
| Route of Administration | Parenteral |
| Storage | Store the unopened vial at room temperature between 20°C and 25°C (68°F to 77°F). Protect from light and moisture. After reconstitution, the solution should be used according to the instructions provided by the manufacturer or hospital pharmacy. Reconstituted solutions may be stored in the refrigerator for a limited time as directed. Do not freeze. Keep out of reach of children. |
| Shelf Life | The shelf life of the unopened vial is typically 24 months from the date of manufacture, but the exact expiry date is printed on the pack. Once reconstituted, the solution should be used within the time specified by the manufacturer or hospital pharmacy, usually within a few hours if kept at room temperature or up to 24 hours if refrigerated. Do not use after the expiry date. |
| WHO Guideline | Not established from the available information for this specific combination product. Meropenem is included in some World Health Organization guidance for serious bacterial infections, but the meropenem-sulbactam combination is not specifically addressed in all WHO documents. Always follow local hospital guidelines and susceptibility results. |
| ICMR Guideline | Not established from the available information for this specific combination product. The Indian Council of Medical Research has published guidance on antimicrobial use and resistance, and meropenem is included in some hospital antibiotic policies. The meropenem-sulbactam combination should be used according to local antibiogram and institutional policy. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works through two complementary actions. Meropenem is a carbapenem antibiotic that binds to penicillin-binding proteins on the bacterial cell wall and prevents the cross-linking of peptidoglycan, which is essential for bacterial structure and survival. This leads to weakening of the cell wall, cell lysis, and bacterial death. Sulbactam is a beta-lactamase inhibitor that binds irreversibly to certain beta-lactamase enzymes produced by bacteria, preventing them from breaking down meropenem. By blocking these enzymes, sulbactam helps meropenem remain active against bacteria that would otherwise be resistant. Sulbactam also has some intrinsic antibacterial activity against certain organisms such as Acinetobacter species. Together, the two ingredients broaden the antibacterial coverage and help overcome resistance mediated by beta-lactamase enzymes.
Mechanism Steps
💡 How to Take almero-s 1.5gm injection
Strength: This medicine is supplied as a sterile powder for injection containing 1000 mg of meropenem and 500 mg of sulbactam in a single vial, for a total strength of 1.5 g. It is reconstituted and diluted before intravenous infusion.
Dosage Information
| Adult Dosage | The dose of this medicine must be individualized by a qualified clinician based on the type and severity of infection, the patient's age, weight, kidney function, and liver function. For serious infections in adults with normal kidney function, meropenem is often given as 500 mg to 1 g every 8 hours, and in some severe infections up to 2 g every 8 hours may be used. Sulbactam is combined in a fixed ratio in this product. The infusion is usually given over 15 to 30 minutes, but longer infusions may be used in some situations. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information for this specific combination product. Meropenem is used in children for serious infections, but the addition of sulbactam and the exact dosing for this combination require specialist evaluation. Consult a pediatrician or pediatric infectious disease specialist for dosing in children. |
| Elderly Dosage | Elderly patients may have reduced kidney function, which can increase the blood levels of this medicine and the risk of side effects such as seizures. The dose should be adjusted based on kidney function. Elderly patients should be monitored closely for changes in kidney function, mental status, and signs of infection. Dose must be individualized by a qualified clinician. |
| Renal Impairment | The dose of this medicine must be reduced in patients with kidney impairment. For meropenem, the usual approach is to adjust the dose or the dosing interval based on creatinine clearance. Patients with a creatinine clearance of 26 to 50 mL/min may receive the usual dose every 12 hours, and those with a creatinine clearance of 10 to 25 mL/min may receive half the usual dose every 12 hours. Patients on hemodialysis may need a dose after each dialysis session. Sulbactam also requires dose adjustment in renal impairment. Dose must be individualized by a qualified clinician based on measured kidney function. |
| Hepatic Impairment | Mild to moderate liver impairment usually does not require a dose adjustment for this medicine. However, patients with severe liver disease should be monitored closely because the safety and effectiveness have not been well studied. Liver function tests may be checked during treatment. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum daily dose depends on the indication, the severity of infection, and kidney function. In adults with normal kidney function, meropenem doses up to 2 g every 8 hours have been used in some severe infections, which equals a maximum of 6 g per day. The sulbactam component in this product is fixed at 500 mg per 1 g of meropenem. The exact maximum daily dose must be determined by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of almero-s 1.5gm injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Valproic acid | Major | |
| Probenecid | Major | |
| Aminoglycosides | Major | |
| Amphotericin B | Major | |
| Warfarin | Moderate | |
| Oral contraceptives | Moderate | |
| Mycophenolate mofetil | Moderate | |
| Allopurinol | Minor | |
| Methotrexate | Minor | |
| Cyclosporine | Moderate |
🚨 Major Interactions
- Valproic acid and divalproex sodium
- Probenecid
- Other nephrotoxic drugs such as aminoglycosides or amphotericin B
⚡ Moderate Interactions
- Warfarin
- Oral contraceptives
- Mycophenolate mofetil
🍷 Alcohol Interaction
Alcohol should be avoided while receiving this medicine. Alcohol can increase the risk of liver problems, worsen nausea and dizziness, and may interfere with your body's ability to fight infection. It is best to wait until your doctor confirms that you have recovered and completed treatment before drinking alcohol.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known severe allergy to meropenem, sulbactam, or other carbapenem antibiotics","Known severe allergy to penicillins or beta-lactam antibiotics","History of anaphylaxis to beta-lactam antibiotics","Use of valproic acid or divalproex sodium, because of a significant interaction","Not for use in patients with viral infections such as the common cold or influenza"]
⚠️ Warnings & Precautions
["Serious allergic reactions can occur, including anaphylaxis. Tell your doctor about any antibiotic allergies before treatment.","Clostridioides difficile-associated diarrhea can develop during or after treatment. Report new diarrhea to your doctor.","Seizures have been reported, especially in patients with kidney problems or central nervous system disorders. Use with caution in these patients.","Kidney function should be monitored, and the dose adjusted in patients with renal impairment.","Liver function should be monitored if symptoms of liver injury appear.","Prolonged use may lead to overgrowth of non-susceptible organisms, including fungi.","This medicine should be used only for bacterial infections and not for viral illnesses.","Patients with phenylketonuria should check with their doctor because some formulations may contain phenylalanine.","Use with caution in elderly patients and in those with multiple medical conditions.","Do not use this medicine without a confirmed or strongly suspected bacterial infection."]
🤱 Lactation Safety
Meropenem and sulbactam are excreted in small amounts in breast milk. The amount is generally low, but the effects on a nursing infant are not fully established. Breastfeeding may be continued if your doctor decides it is safe, but you should discuss the risks and benefits with your doctor. If you notice diarrhea or thrush in your baby, contact your pediatrician.
💊 Overdose Management
Overdose with this medicine is unlikely because it is given by healthcare professionals. If an excessive dose is given, treatment should be supportive and symptomatic. Kidney function should be monitored closely because high levels can increase the risk of seizures and other nervous system effects. There is no specific antidote. In patients with kidney failure, hemodialysis may help remove meropenem and sulbactam from the blood. Contact a poison control center or emergency department if you suspect an overdose.
⏰ Missed Dose
Because this medicine is given by a healthcare professional in a hospital or clinic, missed doses are managed by your medical team. If you miss an appointment for your infusion, contact your doctor or clinic as soon as possible to reschedule. Do not try to catch up by taking extra doses on your own. If you are receiving this medicine at home through a home infusion service, follow the schedule provided by your nurse and call the service if you miss a dose.
Additional Safety Advice
This medicine must be given only by a healthcare professional through an intravenous line. Do not attempt to self-administer this injection at home. Tell your doctor about all allergies, especially to antibiotics, before receiving this medicine. Inform your doctor if you have kidney disease, liver disease, epilepsy, or a history of seizures, because the dose may need adjustment. Complete the full course prescribed by your doctor even if you start feeling better, as stopping early can allow the infection to return and may promote antibiotic resistance. Report any new diarrhea, rash, swelling, or difficulty breathing immediately. Blood tests may be needed to check kidney function, liver function, and blood cell counts during treatment. Avoid alcohol while receiving this medicine because it may worsen side effects and strain your liver. If you are pregnant, planning pregnancy, or breastfeeding, discuss the risks and benefits with your doctor before this medicine is used.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to have reduced kidney function, which can increase the blood levels of this medicine and the risk of side effects such as seizures and confusion. The dose should be adjusted based on kidney function, and elderly patients should be monitored closely for changes in mental status, kidney function, and signs of infection. They may also be more sensitive to diarrhea and dehydration.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, discuss this medicine with your doctor before starting treatment. This medicine should be used during pregnancy only when clearly needed. Your doctor will consider the benefits and risks. If you become pregnant while receiving this medicine, tell your doctor right away.
🏥 Post-Surgery Considerations
This medicine is often used after surgery to treat or prevent serious infections. After surgery, your doctor will monitor your wound, temperature, and blood tests. Keep the surgical area clean and follow your surgeon's instructions. Report any increasing pain, redness, swelling, or fever after surgery.
🦷 Dental Procedures
Tell your dentist that you are receiving this medicine before any dental procedure. In general, this antibiotic does not require special precautions for dental work, but your dentist may want to coordinate with your doctor if you are still recovering from a serious infection. Good oral hygiene is important during treatment.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While receiving this medicine, you may feel tired or weak, so avoid strenuous exercise until you have recovered. Light activity such as short walks may be helpful if your doctor allows it. If you feel dizzy, have a fever, or have difficulty breathing, rest and contact your doctor. Do not start a new exercise program without talking to your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is usually given in a hospital, so you may need to take time off work during treatment. You may feel tired, dizzy, or uncomfortable, and you should not drive or operate heavy machinery if you feel unwell. Ask your doctor when you can safely return to work and normal activities. If you have a physically demanding job, you may need more time to recover.
🛑 When to Stop This Medicine
Do not stop this medicine on your own. Your doctor will decide when to stop based on your symptoms, test results, and the type of infection. Stopping early can allow the infection to return and can lead to antibiotic resistance. If you develop serious side effects, your doctor may stop the medicine and switch to another treatment. Always talk to your doctor before stopping.
📅 Long-Term Use Effects
Long-term use of this medicine is not common because it is usually given for a limited period to treat serious infections. Prolonged use can increase the risk of antibiotic resistance, fungal overgrowth, and Clostridioides difficile-associated diarrhea. Kidney and liver function should be monitored if treatment is extended. If you need long-term antibiotics, your doctor will review the risks and benefits regularly and may switch to a different medicine when appropriate.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Depending on the bacteria and susceptibility results, your doctor may choose a different antibiotic such as piperacillin-tazobactam, ceftazidime-avibactam, or another carbapenem.
Evidence: Well-establishedFor some infections, draining an abscess or removing infected tissue is necessary along with antibiotics.
Evidence: Well-establishedFluids, fever control, and nutrition support are important parts of treating serious infections.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions reported for this medicine. However, if you are due for a vaccine, tell your doctor that you are receiving this antibiotic. In general, antibiotics do not prevent most vaccines from working, but your doctor may prefer to wait until you have recovered from the acute infection before giving certain vaccines.
📦 Storage Guide
✅ DO
Store the unopened vial at room temperature between 20°C and 25°C.
❌ DON'T
Do not freeze the vial or the reconstituted solution.
✅ DO
Keep the vial in its original carton to protect it from light.
❌ DON'T
Do not store in a bathroom cabinet or in direct sunlight.
✅ DO
Use the reconstituted solution within the time recommended by the manufacturer or hospital pharmacy.
❌ DON'T
Do not use the solution if it is cloudy or contains particles.
✅ DO
Keep out of reach of children.
❌ DON'T
Do not transfer the medicine to unmarked containers.
✈️ Traveling with This Medicine
This medicine is usually given in a hospital or clinic, so travel planning should be discussed with your doctor. If you need to travel while receiving treatment, carry a copy of your prescription and a letter from your doctor explaining the medicine and the reason for treatment. Keep the medicine in its original packaging and follow the storage instructions. If you are flying, check the airline's rules for carrying medical supplies and keep the medicine in your hand luggage. Plan your doses around your travel schedule with your doctor's help, and identify a hospital or clinic at your destination in case you need urgent care.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start to feel better within 24 to 72 hours, but the full effect depends on the type of infection and your overall health. It is important to complete the full course prescribed by your doctor.
A: This medicine is usually given in a hospital or clinic by a healthcare professional. In some cases, home infusion services may be arranged, but only under medical supervision.
A: Contact your doctor or clinic as soon as possible. Do not try to give yourself an extra dose to catch up.
A: It is best to avoid alcohol during treatment because it can worsen side effects and strain your liver.
A: The dose may need to be adjusted if you have kidney disease. Your doctor will check your kidney function and decide the right dose for you.
A: This medicine should be used during pregnancy only if clearly needed. Your doctor will weigh the benefits and risks. Tell your doctor if you are pregnant or planning pregnancy.
A: Seek immediate medical help for swelling of the face or throat, difficulty breathing, severe rash, seizures, severe diarrhea, or unusual bleeding.
A: Yes, it can interact with medicines such as valproic acid, probenecid, warfarin, and some kidney-toxic drugs. Tell your doctor about all medicines you take.
🤔 Common Patient Concerns
🔄 Substitutes for almero-s 1.5gm injection
View AllAlternative brands with exact same active ingredient:
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wemero s 1000mg/500mg injectionTreatwell Biotech ₹750.00 72.7% CHEAPER
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mero sb injectionAristo Pharmaceuticals Pvt Ltd ₹795.47 71.1% CHEAPER
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kupen sb 1000mg/500mg injectionHetero Drugs Ltd ₹802.67 70.8% CHEAPER
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ibimero s 1000mg/500mg injectionIndiabulls pharmaceutical ltd ₹805.55 70.7% CHEAPER
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eupen s injectionNeon Laboratories Ltd ₹878.90 68% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any infection, including viral fevers.
Fact: This medicine only works against susceptible bacteria. It does not treat viral infections such as the common cold or influenza. - Myth: You can stop this medicine as soon as you feel better.
Fact: You must complete the full course prescribed by your doctor. Stopping early can allow the infection to return and can promote antibiotic resistance. - Myth: This medicine is safe for everyone without any monitoring.
Fact: This medicine requires monitoring of kidney function, liver function, and blood counts, especially in seriously ill patients. - Myth: This medicine can be taken as a tablet instead of an injection.
Fact: This product is an intravenous injection. It cannot be taken by mouth because it is not absorbed well from the gut. - Myth: More antibiotic is always better.
Fact: Higher doses can increase the risk of side effects such as seizures and kidney problems. The dose must be individualized by a doctor.
🔄 Alternative Options
Generic Alternatives
- Meropenem injection
- Sulbactam injection
- Meropenem and sulbactam injection
Brand Alternatives
- Almero-S 1.5gm Injection