alkazar liquid - Disodium Hydrogen Citrate (1.25gm) medicine

Alkazar Liquid: Complete Medicine Guide

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🏭 Austro Labs 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for urinary alkalinization and symptomatic relief of UTI.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe abdominal pain or cramping that does not go away.
  • Blood in urine or stool.
  • Signs of allergic reaction: rash, itching, swelling of face, lips, or throat, difficulty breathing.
  • Muscle twitching, confusion, or irregular heartbeat (signs of metabolic alkalosis).
  • Sudden weight gain or swelling in legs (signs of fluid retention).
  • Fever with chills and back pain (may indicate kidney infection).
  • Decreased urine output or inability to urinate.

If experiencing severe symptoms, call emergency services immediately.

What is alkazar liquid used for?

This medicine is an oral liquid containing disodium hydrogen citrate, used to relieve burning and discomfort during urination by making urine less acidic. It is not an antibiotic and does not treat the infection itself.

  • Generic Name: Disodium Hydrogen Citrate
  • Manufacturer: Austro Labs
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 alkazar liquid के बारे में (Hindi Summary)

उपयोग: यह दवा मूत्र पथ के संक्रमण में जलन और दर्द को कम करने के लिए दी जाती है। यह पेशाब को कम अम्लीय बनाकर आराम पहुंचाती है। यह किडनी की पथरी के कुछ प्रकारों में भी मदद कर सकती है। यह एंटीबायोटिक नहीं है, इसलिए संक्रमण के इलाज के लिए डॉक्टर द्वारा बताई गई अन्य दवाएं भी लेनी चाहिए।

साइड इफेक्ट्स: आमतौर पर यह दवा सुरक्षित मानी जाती है, लेकिन कुछ लोगों को जी मिचलाना, दस्त, पेट में ऐंठन या ज्यादा प्यास लग सकती है। ये लक्षण आमतौर पर हल्के होते हैं और खाने के साथ लेने पर कम हो जाते हैं। अगर आपको मांसपेशियों में ऐंठन, भ्रम या दिल की धड़कन अनियमित लगे तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी स्वास्थ्य समस्याओं के बारे में बताएं, खासकर किडनी, दिल या ब्लड प्रेशर की बीमारी हो तो। यह दवा सोडियम युक्त है, इसलिए नमक कम खाने वाले मरीज इसे बिना डॉक्टर की सलाह के न लें। कुछ एंटीबायोटिक्स के साथ लेने पर इसका असर कम हो सकता है, इसलिए दोनों दवाओं के बीच कम से कम 2 घंटे का अंतर रखें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लेकर ही इसका इस्तेमाल करें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 alkazar liquid Uses & Benefits

[{"condition":"Urinary tract infections (symptomatic relief)","description":"This medicine helps relieve burning and pain during urination by making the urine less acidic, but it does not treat the infection itself.","evidence":"Well-established"},{"condition":"Uric acid kidney stones","description":"It alkalinizes the urine, which can help dissolve uric acid stones and prevent their formation.","evidence":"Well-established"},{"condition":"Cystine kidney stones","description":"Alkalinization of urine increases the solubility of cystine, reducing stone formation.","evidence":"Moderate"},{"condition":"Metabolic acidosis (mild to moderate)","description":"It can be used as an alkalinizing agent in certain types of metabolic acidosis, under medical supervision.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Chemotherapy-induced nausea","description":"Sometimes used to alkalinize urine and prevent certain chemotherapy drugs from causing bladder irritation.","evidence":"Limited"},{"condition":"Rhabdomyolysis prevention","description":"Alkalinization of urine may help prevent kidney damage from muscle breakdown products.","evidence":"Limited"}]

Primary treatment for: Urinary tract infections (symptomatic relief)

Also treats: Uric acid kidney stones, Cystine kidney stones, Metabolic acidosis

📋 Drug Information

Generic Name(s)Disodium Hydrogen Citrate
Brand NameAlkasol Oral Solution
ManufacturerAustro Labs
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassUROLOGY
Action ClassUricosuric agent-gout
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a cool, dry place. Protect from direct sunlight. Do not freeze.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always dilute this medicine in a glass of water before taking it to reduce stomach irritation.
2
Take this medicine after meals to minimize nausea and stomach cramps.
3
If you are on antibiotics like tetracycline or ciprofloxacin, take them at least 2 hours before or after this medicine.
4
Monitor your urinary symptoms; if burning persists beyond 3 days, consult your doctor as antibiotics may be needed.
5
Patients with heart or kidney disease should use this medicine only under strict medical supervision due to its sodium content.
6
Stay well hydrated by drinking plenty of water throughout the day to help flush the urinary tract.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Burning during urination
This medicine is commonly prescribed for this symptom.
Likely Use
Frequent urination
It helps reduce urgency and frequency by alkalinizing urine.
Likely Use
Fever
This medicine is not a fever reducer; fever may indicate infection requiring antibiotics.
Not Primary
Joint pain
This medicine is not used for joint pain.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionDisodium hydrogen citrate is rapidly absorbed from the gastrointestinal tract after oral administration. The absorption is not significantly affected by food, but taking it with food may reduce gastrointestinal discomfort.
DistributionAfter absorption, citrate is distributed throughout the body, primarily in the extracellular fluid. It does not bind significantly to plasma proteins.
Protein BindingNot established from the available information.
MetabolismCitrate is metabolized in the liver and other tissues via the Krebs cycle to bicarbonate and carbon dioxide. This metabolism is efficient and rapid.
Half-LifeThe half-life of citrate is approximately 30 minutes to 1 hour, but the alkalinizing effect on urine lasts longer due to the production of bicarbonate.
ExcretionThe metabolites, primarily bicarbonate, are excreted in the urine. Unmetabolized citrate may also be excreted in urine to a small extent.
BioavailabilityNot established from the available information.
Onset of ActionThe alkalinizing effect on urine typically begins within 1 to 2 hours after oral administration.
Peak Plasma TimePeak plasma levels of citrate are reached within 1 to 2 hours after ingestion.
Duration of ActionThe effect on urinary pH lasts for approximately 4 to 6 hours after a single dose, depending on the dose and individual factors.

How It Works

This medicine works by providing citrate ions, which are metabolized in the body to bicarbonate. Bicarbonate is a base that neutralizes excess hydrogen ions, thereby reducing the acidity of the urine. This alkalinization effect helps relieve the burning sensation associated with acidic urine and creates an environment that is less favorable for the formation of certain types of kidney stones. Additionally, the citrate ion itself can inhibit the crystallization of calcium oxalate and calcium phosphate, further reducing stone risk.

Mechanism Steps

1
Ingestion and absorption: Disodium hydrogen citrate is swallowed and absorbed from the gastrointestinal tract.
2
Metabolism to bicarbonate: In the body, citrate is metabolized in the liver and other tissues to bicarbonate, which acts as a base.
3
Neutralization of acid: Bicarbonate neutralizes excess hydrogen ions in the blood and urine, raising the pH.
4
Urinary alkalinization: The increased bicarbonate is excreted in the urine, making it less acidic and relieving symptoms.

💡 How to Take alkazar liquid

Strength: Liquid containing disodium hydrogen citrate 1.25 g per 5 mL (as per product label).

1Shake the bottle well before use.
2Measure the prescribed dose using a measuring cup or spoon.
3Dilute the dose in a glass of water (about 100-150 mL).
4Drink the mixture slowly.
5Take after meals to reduce stomach upset.
6Follow with a glass of water if desired.

Dosage Information

Adult DosageThe usual adult dose is 10-15 mL of the liquid (containing 1.25 g of disodium hydrogen citrate per 5 mL or as per the product label) diluted in a glass of water, taken 3 to 4 times daily after meals. The exact dose and frequency depend on the condition being treated and the patient's response. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the sodium content and electrolyte effects. Use with caution and monitor renal function and electrolytes. Dose must be individualized by a qualified clinician.
Renal ImpairmentUse with caution in patients with renal impairment. Dose adjustment may be necessary based on creatinine clearance. Consult a nephrologist or clinician for individualized dosing.
Hepatic ImpairmentNo specific dose adjustment is established for hepatic impairment. Use with caution and consult a clinician.
Maximum Daily DoseThe maximum daily dose should not exceed 30 mL of the liquid (or as directed by the physician). Do not exceed the recommended dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset and nausea.
Water
Dilute in a glass of water
Helps the medicine mix well and reduces irritation.
High-sodium foods
Limit intake
This medicine contains sodium; excess sodium can worsen fluid retention.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of alkazar liquid

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food or dilute with water. If persistent, consult your doctor.
Diarrhea (Common (5-10%))
Stay hydrated. If severe or persistent, consult your doctor.
Stomach cramps (Common (5-10%))
Take with meals. If cramps are severe, contact your doctor.
Increased thirst (Common (5-10%))
Drink plenty of water. This is usually harmless.

🚨 Serious Side Effects

Metabolic alkalosis (Rare (<0.1%))
Seek immediate medical attention if you experience muscle twitching, confusion, or irregular heartbeat.
Fluid retention and worsening of heart failure (Rare (<0.1%))
If you have heart failure, monitor for weight gain or swelling. Contact your doctor immediately if these occur.
Severe allergic reaction (Very rare (<0.01%))
Seek emergency help if you experience rash, swelling of face or throat, or difficulty breathing.

⚠️ Rare Side Effects

Hypernatremia
Monitor for excessive thirst, confusion, or seizures. Seek immediate medical attention.
Hypokalemia
Report muscle weakness or cramps to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Tetracycline Major
Ciprofloxacin Major
Lithium Major
Furosemide Moderate
Prednisolone Moderate
Aluminum hydroxide Minor

🚨 Major Interactions

  • Tetracycline antibiotics (e.g., doxycycline)
  • Fluoroquinolone antibiotics (e.g., ciprofloxacin)
  • Lithium

⚡ Moderate Interactions

  • Diuretics (e.g., furosemide)
  • Corticosteroids

🍷 Alcohol Interaction

Alcohol may increase the risk of stomach irritation and can worsen dehydration. It is advisable to avoid alcohol while taking this medicine, especially if you have a urinary tract infection.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Severe renal impairment","Uncontrolled hypertension","Heart failure","Hypernatremia","Metabolic alkalosis","Hypersensitivity to citrates"]

⚠️ Warnings & Precautions

["Contains sodium; caution in patients on sodium-restricted diet.","May cause metabolic alkalosis with prolonged high doses.","Use with caution in patients with kidney disease or heart failure.","Not a substitute for antibiotics in urinary tract infections.","Consult doctor before use in pregnancy or breastfeeding."]

🤱 Lactation Safety

It is not known whether disodium hydrogen citrate passes into breast milk. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

Overdose may cause metabolic alkalosis, hypernatremia, and gastrointestinal upset. Treatment is supportive and symptomatic. In case of overdose, seek immediate medical attention. Do not induce vomiting unless instructed by a healthcare professional.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Before taking this medicine, inform your doctor if you have a history of kidney disease, heart failure, high blood pressure, or any condition requiring a low-sodium diet. This medicine contains sodium, so it may not be suitable for you if you are on salt restriction. Do not take this medicine if you are allergic to citrates or any of the inactive ingredients. Use with caution if you are pregnant or breastfeeding, and only after consulting your doctor. Avoid taking this medicine at the same time as certain antibiotics (such as tetracyclines or fluoroquinolones) because it can reduce their absorption; separate the doses by at least 2 hours. Do not exceed the recommended dose, as excessive intake can lead to alkalosis. Keep out of reach of children. If you are scheduled for any surgery or dental procedure, tell your healthcare provider that you are taking this medicine. Always follow your doctor's instructions regarding dosage and duration of treatment.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more sensitive to the sodium content and electrolyte effects of this medicine. They may be at higher risk of fluid retention, hypertension, and metabolic alkalosis. Use with caution and monitor renal function and electrolytes regularly. Dose adjustment may be necessary.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. It is not known whether it is safe during pregnancy. Your doctor will weigh the benefits and risks.

🏥 Post-Surgery Considerations

After surgery, this medicine may be used to alkalinize urine and prevent complications such as blood clots in the urinary tract. However, use only under medical supervision, especially if you have heart or kidney issues.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine before any dental procedure. It is generally safe, but your dentist may need to know for medical history purposes.

💚 Lifestyle Tips for Better Results

🏃
Drink plenty of water throughout the day to help flush your urinary system.
🥗
Avoid holding urine for long periods; urinate when you feel the urge.
😴
Maintain good genital hygiene to prevent urinary tract infections.
💧
Limit intake of caffeine and alcohol, which can irritate the bladder.
🧘
Include fruits and vegetables rich in vitamin C to boost immunity.
🌞
Practice safe sex to reduce the risk of urinary tract infections.

🏋️ Exercise Considerations

There are no specific exercise restrictions while taking this medicine. However, if you have a urinary tract infection, rest and avoid strenuous activities until symptoms improve. Stay hydrated during exercise.

🥗 Diet Recommendations

Drink at least 8-10 glasses of water daily.
Avoid spicy and acidic foods that can irritate the bladder.
Include yogurt and probiotics to support urinary health.
Reduce salt intake to prevent fluid retention.
Eat a balanced diet rich in fiber and vitamins.

💼 Impact on Daily Work & Life

This medicine is unlikely to affect your ability to drive or operate machinery. However, if you experience dizziness or nausea, avoid these activities until you feel better. It does not cause drowsiness. You can continue your normal daily activities, but take the medicine as prescribed.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience severe side effects or your symptoms worsen, contact your doctor immediately. For short-term use, follow the prescribed duration. For long-term use, your doctor will determine when to stop based on your condition and test results.

📅 Long-Term Use Effects

Long-term use of this medicine should be monitored by a doctor. Prolonged use can lead to electrolyte imbalances such as hypernatremia or hypokalemia, and metabolic alkalosis. Regular monitoring of kidney function and electrolytes is advised. It is generally safe for extended use when prescribed for conditions like kidney stones, but the dose should be adjusted based on periodic evaluations.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Increased water intake

Drinking plenty of water can help dilute urine and reduce burning.

Evidence: Well-established
Cranberry extract

May help prevent urinary tract infections by preventing bacteria from adhering to the bladder wall.

Evidence: Moderate
Probiotics

Can help maintain a healthy balance of bacteria in the urinary tract.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. You can receive vaccinations as scheduled. However, if you are acutely ill with a urinary tract infection, consult your doctor before vaccination.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription to avoid issues at customs. Store it in a cool, dry place away from direct sunlight. If you are crossing time zones, adjust your dosing schedule to maintain regular intervals, but consult your doctor for specific advice. Always pack enough for your trip and carry it in your hand luggage if flying.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with recurrent urinary tract infections.
She experienced burning and frequent urination. Her doctor prescribed this medicine along with an antibiotic. She took the liquid diluted in water after meals. Within a day, the burning sensation reduced significantly. She completed the antibiotic course and continued this medicine for a week. She learned to separate the doses of the antibiotic and this medicine by 2 hours to ensure effectiveness.
💡 Lesson: This medicine provides symptomatic relief but must be used alongside antibiotics for infection. Proper timing with other medicines is crucial.
👤 A 50-year-old man with a history of uric acid kidney stones.
He was advised to take this medicine regularly to alkalinize his urine. He initially experienced mild diarrhea, which subsided when he started taking it with food. Over several months, his urine pH improved, and follow-up scans showed no new stones. He also increased his water intake as recommended.
💡 Lesson: Long-term use under medical supervision can help prevent stone formation. Taking the medicine with food improves tolerability.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts working within 1 to 2 hours after taking it, providing relief from burning and discomfort.

Q: Can I take this medicine with food?

A: Yes, it can be taken with or without food, but taking it with food may reduce stomach upset.

Q: Is this medicine safe for children?

A: Pediatric dosing is not established. Consult a pediatrician for appropriate use in children.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for alkazar liquid

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure urinary tract infections.
    Fact: This medicine only relieves symptoms by alkalinizing urine; it does not kill bacteria. Antibiotics are needed to treat the infection.
  • Myth: It is safe to take this medicine without a prescription.
    Fact: It should be used only under medical supervision, especially if you have kidney or heart problems.
  • Myth: This medicine can be taken with any other medication.
    Fact: It can interact with certain antibiotics and other drugs. Always inform your doctor about all medicines you take.

🔄 Alternative Options

Generic Alternatives

  • Disodium hydrogen citrate oral solution

Brand Alternatives

  • Alkazar Liquid

📊 Comparison with Similar Medicines

[{"medicine":"Disodium hydrogen citrate","class":"Urinary alkalinizer","main_use":"Symptomatic relief of UTI, kidney stones","route":"Oral"},{"medicine":"Potassium citrate","class":"Urinary alkalinizer","main_use":"Kidney stones, UTI","route":"Oral"},{"medicine":"Sodium citrate","class":"Urinary alkalinizer","main_use":"UTI, metabolic acidosis","route":"Oral"}]

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