alkacee 1.42gm syrup - Disodium Hydrogen Citrate (1.42gm) medicine

Alkacee 1.42gm Syrup: Complete Medicine Guide

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🏭 V.S. Healthcare Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 18, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for symptomatic relief of UTI and uric acid stones.
Reviewed by
SaathiMed Expert Panel | Oct 18, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in urine or stool
  • Severe abdominal or flank pain
  • Difficulty breathing or chest pain
  • Swelling of face, lips, or throat
  • Confusion or irregular heartbeat
  • Decreased urine output
  • High fever with chills

If experiencing severe symptoms, call emergency services immediately.

What is alkacee 1.42gm syrup used for?

This medicine is a urinary alkalinizer used to relieve burning and discomfort from urinary tract infections and to prevent uric acid kidney stones. It works by making urine less acidic.

  • Generic Name: Disodium Hydrogen Citrate (1.42gm)
  • Manufacturer: V.S. Healthcare Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 alkacee 1.42gm syrup के बारे में (Hindi Summary)

उपयोग: यह दवा मूत्र पथ के संक्रमण में जलन और असुविधा को कम करने के लिए उपयोग की जाती है। यह मूत्र को कम अम्लीय बनाकर काम करती है, जिससे जलन कम होती है। यह यूरिक एसिड की पथरी को रोकने में भी मदद कर सकती है। यह एंटीबायोटिक नहीं है, इसलिए संक्रमण के इलाज के लिए डॉक्टर द्वारा बताई गई अन्य दवाओं के साथ लेनी चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में पेट में हल्की परेशानी, जी मिचलाना और दस्त शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर पेट में तेज दर्द, हाथ-पैरों में सूजन या सांस लेने में कठिनाई हो, तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। दिन में खूब पानी पिएं। बिना डॉक्टर की सलाह के कोई अन्य दवा न लें। अगर आपको उच्च रक्तचाप, हृदय रोग या गुर्दे की समस्या है, तो डॉक्टर को बताएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 alkacee 1.42gm syrup Uses & Benefits

[{"condition":"Urinary tract infections (UTIs)","description":"Provides symptomatic relief from burning and urgency by alkalinizing urine, reducing irritation.","evidence":"Well-established"},{"condition":"Uric acid kidney stones","description":"Helps dissolve and prevent uric acid stones by increasing urine pH.","evidence":"Well-established"},{"condition":"Cystitis","description":"Reduces bladder discomfort associated with inflammation.","evidence":"Commonly used"},{"condition":"Metabolic acidosis (mild)","description":"May be used to correct mild metabolic acidosis in certain clinical settings.","evidence":"Limited"}]

Off-label uses: [{"condition":"Chemotherapy-induced cystitis","description":"Sometimes used to alleviate bladder irritation from certain chemotherapy drugs.","evidence":"Limited"}]

Primary treatment for: Urinary tract infections

Also treats: Uric acid kidney stones, Cystitis

📋 Drug Information

Generic Name(s)Disodium Hydrogen Citrate (1.42gm)
Brand Namealkacee 1.42gm syrup
ManufacturerV.S. Healthcare Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassUROLOGY
Action ClassUricosuric agent-gout
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with a full glass of water to enhance its effect.
2
Drink plenty of fluids throughout the day to help flush your urinary system.
3
Do not take antacids within 2 hours of this medicine, as they may reduce its effectiveness.
4
If you have high blood pressure or heart disease, monitor your sodium intake and inform your doctor.
5
Do not use this medicine for more than 7 days without consulting your doctor.
6
Report any signs of fluid retention, such as swelling in ankles or feet, immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Burning during urination
This medicine is commonly prescribed for this.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
❌
Flank pain
This medicine may not be appropriate; consult a doctor.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionDisodium hydrogen citrate is rapidly absorbed from the gastrointestinal tract after oral administration.
DistributionCitrate and its metabolites distribute throughout the extracellular fluid and are excreted primarily in urine.
Protein BindingNot established from the available information.
MetabolismCitrate is metabolized in the liver and other tissues via the Krebs cycle to bicarbonate and carbon dioxide.
Half-LifeNot established from the available information.
ExcretionMetabolites are excreted mainly in urine as bicarbonate, with some citrate excreted unchanged.
BioavailabilityNot established from the available information.
Onset of ActionSymptomatic relief may begin within a few hours after the first dose.
Peak Plasma TimeNot established from the available information.
Duration of ActionThe effect on urine pH lasts for several hours; dosing is typically repeated every 4 to 6 hours as needed.

How It Works

This medicine works by increasing the pH of urine, making it more alkaline. Disodium hydrogen citrate is a salt of citric acid that, when metabolized, produces bicarbonate. Bicarbonate neutralizes excess hydrogen ions in the urine, thereby reducing acidity. This alkalinization helps relieve the burning sensation during urination and creates an environment less favorable for the formation of certain types of kidney stones. It does not have antibacterial properties.

Mechanism Steps

1
Ingestion and absorption: Disodium hydrogen citrate is swallowed and absorbed from the gastrointestinal tract.
2
Metabolism to bicarbonate: In the body, citrate is metabolized to bicarbonate, which acts as a buffer.
3
Alkalinization of urine: Bicarbonate is excreted in urine, where it neutralizes hydrogen ions, raising urine pH.
4
Symptomatic relief: The reduced acidity lessens irritation of the bladder and urethra, relieving burning and urgency.

💡 How to Take alkacee 1.42gm syrup

Strength: Syrup containing disodium hydrogen citrate 1.42 grams per dose.

1Measure the prescribed amount of syrup using a measuring cup or spoon.
2Mix with a glass of water if desired.
3Take orally, with or without food.
4Drink plenty of water throughout the day.
5Follow the dosing schedule as advised by your doctor.

Dosage Information

Adult DosageThe usual adult dose is 1.42 grams (one dose) dissolved in water, taken up to four times daily, depending on the condition being treated. For urinary tract infections, it is often taken every 4 to 6 hours as needed for symptom relief. For kidney stone prevention, the dose may be adjusted based on urine pH. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the sodium load and should use with caution. Dose adjustment may be needed based on kidney function. Consult a doctor.
Renal ImpairmentUse with caution in renal impairment. Dose adjustment may be required. Consult a doctor.
Hepatic ImpairmentNo specific dose adjustment established. Use with caution in severe liver disease.
Maximum Daily DoseThe maximum daily dose should not exceed 4 doses (5.68 grams) in 24 hours, unless directed by a doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
No specific restriction
No known interaction.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of alkacee 1.42gm syrup

✅ Common Side Effects

Mild stomach discomfort (Common (5-10%))
Take with food or milk to reduce discomfort. Consult doctor if persistent.
Nausea (Common (5-10%))
Take with a small snack. If nausea continues, consult your doctor.
Diarrhea (Uncommon (1-5%))
Stay hydrated. If diarrhea is severe or persistent, contact your doctor.

🚨 Serious Side Effects

Severe abdominal pain (Rare (<0.1%))
Seek immediate medical attention.
Swelling of hands, feet, or ankles (Rare (<0.1%))
Contact your doctor promptly; may indicate fluid retention.
Difficulty breathing (Rare (<0.1%))
Seek emergency medical help.

⚠️ Rare Side Effects

Electrolyte imbalance (e.g., hypernatremia)
Report symptoms like confusion, weakness, or irregular heartbeat to your doctor immediately.
Allergic reaction (rash, itching, swelling)
Discontinue and seek medical attention if severe.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Antacids Moderate
Potassium-sparing diuretics Major
Lithium Moderate
Amphetamines Moderate
Methenamine Minor

🚨 Major Interactions

  • Antacids containing aluminum or calcium
  • Potassium-sparing diuretics (e.g., spironolactone)

⚡ Moderate Interactions

  • Lithium
  • Amphetamines

🍷 Alcohol Interaction

Alcohol may worsen dehydration and irritate the bladder, potentially counteracting the benefits of this medicine. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Severe kidney impairment","Uncontrolled hypertension","Heart failure","Low-sodium diet (unless approved by doctor)","Hypersensitivity to any component"]

⚠️ Warnings & Precautions

["Use with caution in patients with hypertension or heart disease.","Avoid in patients on a sodium-restricted diet.","Do not use for prolonged periods without medical supervision.","May affect urine pH tests; inform your doctor.","Keep out of reach of children."]

🤱 Lactation Safety

It is not known if disodium hydrogen citrate passes into breast milk. Consult your doctor before use while breastfeeding.

💊 Overdose Management

Overdose may cause nausea, vomiting, diarrhea, and electrolyte imbalances. Seek immediate medical attention. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Drink plenty of water throughout the day to help flush your urinary system. Avoid taking antacids or other medicines that can change urine acidity without consulting your doctor. If you have high blood pressure, heart failure, or kidney problems, inform your doctor before using this medicine. Do not use this medicine for more than the recommended duration without medical advice. Keep out of reach of children. If you are pregnant or breastfeeding, consult your doctor before use. Report any unusual symptoms, such as swelling, severe headache, or changes in urination, to your healthcare provider promptly.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the sodium content and are at higher risk of electrolyte imbalances. Use with caution and monitor kidney function.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before using this medicine. It should be used during pregnancy only if clearly needed.

🏥 Post-Surgery Considerations

If you have recently undergone surgery, consult your doctor before using this medicine, as it may affect fluid and electrolyte balance.

🦷 Dental Procedures

No specific precautions for dental procedures. Inform your dentist about all medications you are taking.

💚 Lifestyle Tips for Better Results

🏃
Drink at least 8-10 glasses of water daily.
🥗
Avoid holding urine for long periods.
😴
Maintain good genital hygiene.
💧
Limit intake of foods high in purines if you have gout or uric acid stones.
🧘
Include cranberry juice or other urinary-friendly fluids if recommended by your doctor.

🏋️ Exercise Considerations

No specific exercise restrictions, but if you experience dizziness or fatigue, avoid strenuous activities until you feel better.

🥗 Diet Recommendations

Stay well hydrated.
Reduce intake of purine-rich foods like red meat and shellfish if prone to uric acid stones.
Limit salt intake, especially if you have high blood pressure.
Include fruits and vegetables rich in citrate, such as lemons and oranges.

💼 Impact on Daily Work & Life

This medicine generally does not affect your ability to drive or operate machinery. However, if you experience dizziness or drowsiness, avoid these activities until you know how the medicine affects you.

🛑 When to Stop This Medicine

Stop taking this medicine if your symptoms resolve or as advised by your doctor. Do not stop abruptly if you are on long-term therapy without consulting your doctor.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to electrolyte imbalances, particularly high sodium levels, which can affect blood pressure and heart function. Regular monitoring of electrolytes and kidney function is advised. It should only be used long-term under medical supervision.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Increased water intake

Helps flush the urinary system and reduce irritation.

Evidence: Well-established
Cranberry products

May help prevent UTIs by preventing bacterial adhesion.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions known. However, if you have a UTI, consult your doctor about timing of vaccinations.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from direct sunlight. If crossing time zones, continue your regular dosing schedule as closely as possible; consult your doctor for specific advice. Keep enough supply for your trip. Check customs regulations for carrying medications.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 32-year-old woman with recurrent urinary tract infections
She experienced burning during urination and was prescribed this medicine along with an antibiotic. She took the syrup mixed with water every 6 hours. Within a day, the burning sensation reduced significantly. She also increased her water intake. She completed the antibiotic course and used the syrup for 3 days.
💡 Lesson: This medicine provides rapid symptomatic relief but must be used alongside antibiotics for infection. Hydration is key.
👤 A 50-year-old man with a history of uric acid kidney stones
He was advised to take this medicine daily to keep his urine alkaline. He monitored his urine pH with strips as instructed. Over 6 months, he did not form any new stones. He also modified his diet, reducing purine-rich foods.
💡 Lesson: Long-term use under medical supervision can help prevent uric acid stones. Regular monitoring of urine pH is important.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Symptomatic relief may begin within a few hours after the first dose.

Q: Can I take this with antibiotics?

A: Yes, it is often prescribed alongside antibiotics for UTI. However, consult your doctor for proper timing.

Q: Is it safe during pregnancy?

A: Consult your doctor. Use only if clearly needed.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🛑 Myths vs. Facts

  • Myth: This medicine can cure urinary tract infections on its own.
    Fact: This medicine only provides symptomatic relief; it is not an antibiotic and does not kill bacteria.
  • Myth: It is safe to take this medicine for long periods without monitoring.
    Fact: Prolonged use can cause electrolyte imbalances and should be monitored by a doctor.

🔄 Alternative Options

Generic Alternatives

  • Disodium hydrogen citrate 1.42g syrup (various manufacturers)

Brand Alternatives

  • Alkacee 1.42gm syrup

📊 Comparison with Similar Medicines

[{"medicine":"Disodium hydrogen citrate","class":"Urinary alkalinizer","main_use":"UTI symptom relief, uric acid stones","route":"Oral"},{"medicine":"Potassium citrate","class":"Urinary alkalinizer","main_use":"Uric acid stones, metabolic acidosis","route":"Oral"}]

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