alifix ox 200mg/200mg tablet - Cefixime (200mg) + Ofloxacin (200mg) medicine

Alifix OX 200mg/200mg Tablet - Uses, Price, Side Effects

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๐Ÿญ Alisier Drugs Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 29, 2026
โš ๏ธ Hepatotoxicity Risk ๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 29, 2026

What is alifix ox 200mg/200mg tablet used for?

Alifix OX 200mg/200mg Tablet is a combination antibiotic containing Cefixime and Ofloxacin. It is used to treat various bacterial infections such as respiratory tract infections, urinary tract infections, and gastrointestinal infections. Cefixime works by inhibiting bacterial cell wall synthesis, while Ofloxacin inhibits bacterial DNA replication, together effectively killing bacteria.

  • Generic Name: Cefixime + Ofloxacin
  • Manufacturer: Alisier Drugs Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š alifix ox 200mg/200mg tablet Uses & Benefits

Respiratory tract infections, urinary tract infections, gastrointestinal infections, skin and soft tissue infections, sexually transmitted infections

Off-label uses: Typhoid fever, Leprosy, Brucellosis

๐Ÿ“‹ Drug Information

Generic Name(s)Cefixime + Ofloxacin
Brand NameAbixim O Tablet
ManufacturerAlisier Drugs Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassAntibiotic (Cephalosporin + Fluoroquinolone)
Route of AdministrationOral
StorageStore at 20-25ยฐC, protect from light and moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally
DistributionWidely distributed in body tissues and fluids
Protein BindingCefixime: 65%; Ofloxacin: 20-25%
MetabolismCefixime: minimal hepatic; Ofloxacin: hepatic (partial)
Half-LifeCefixime: 3-4 hours; Ofloxacin: 5-7 hours
ExcretionCefixime: renal (biliary); Ofloxacin: renal
BioavailabilityCefixime: 40-50%; Ofloxacin: 98%
Onset of Action1-2 hours
Peak Plasma TimeCefixime: 2-6 hours; Ofloxacin: 1-2 hours
Duration of Action12-24 hours

How It Works

Cefixime inhibits bacterial cell wall synthesis; Ofloxacin inhibits DNA gyrase and topoisomerase IV

Mechanism Steps

1Cefixime binds to penicillin-binding proteins (PBPs) on bacterial cell wall
2Inhibits transpeptidase and carboxypeptidase enzymes
3Disrupts peptidoglycan cross-linking

๐Ÿ’ก How to Take alifix ox 200mg/200mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of alifix ox 200mg/200mg tablet

โœ… Common Side Effects

  • Nausea
  • Diarrhea
  • Headache
  • Dizziness
  • Abdominal pain
  • Vomiting
  • Dyspepsia

๐Ÿšจ Serious Side Effects

  • Tendon rupture
  • Peripheral neuropathy
  • Severe allergic reactions
  • Clostridium difficile colitis
  • QT prolongation
  • Seizures
  • Hepatotoxicity

โš ๏ธ Rare Side Effects

  • Blood dyscrasias
  • Stevens-Johnson syndrome
  • Toxic epidermal necrolysis
  • Interstitial nephritis
  • Anaphylaxis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
NSAIDs Moderate Increased risk of CNS stimulation and seizures
Antacids Minor Reduced absorption of Cefixime

๐Ÿšจ Major Interactions

  • Warfarin
  • Antidiabetic agents
  • NSAIDs
  • Theophylline
  • Corticosteroids

โšก Moderate Interactions

  • Antacids
  • Iron supplements
  • Zinc supplements
  • Sucralfate
  • Probenecid

โ„น๏ธ Minor Interactions

  • Caffeine
  • Cyclosporine
  • Methotrexate

๐Ÿฝ๏ธ Food Interactions

Avoid dairy products, antacids, and iron supplements within 2-4 hours; food may delay absorption

๐Ÿท Alcohol Interaction

Avoid alcohol; may increase CNS effects and hepatotoxicity risk

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity to cephalosporins, fluoroquinolones, or any component; history of tendon disorders with fluoroquinolones; pregnancy (ofloxacin); children <18 years (ofloxacin)

๐Ÿ“Š Monitoring Parameters

Renal function, hepatic function, blood glucose (in diabetics), signs of tendonitis, CNS effects, QT interval

๐Ÿคฑ Lactation Safety

Excreted in breast milk; use with caution

๐Ÿ’Š Overdose Management

Supportive care; gastric lavage; monitor renal function and ECG

โฐ Missed Dose

Take as soon as remembered; skip if almost time for next dose; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 29, 2026

๐Ÿ”— View Profile

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