aknea c gel - Adapalene (0.1% w/w) + Clindamycin (1% w/w) medicine

Aknea C Gel - Uses, Price, Side Effects, and Dosage

4.5 (11 reviews)
๐Ÿญ Genesis Biotech Inc ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 21, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 21, 2026

What is aknea c gel used for?

Aknea C Gel is a combination medicine containing Adapalene (0.1% w/w) and Clindamycin (1% w/w) used to treat acne vulgaris. Adapalene, a retinoid, works by normalizing skin cell turnover and preventing clogged pores, while Clindamycin, an antibiotic, reduces acne-causing bacteria and inflammation. Apply a thin layer once daily at night after cleansing.

  • Generic Name: Adapalene + Clindamycin
  • Manufacturer: Genesis Biotech Inc
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š aknea c gel Uses & Benefits

Acne vulgaris (inflammatory and non-inflammatory lesions)

Off-label uses: Keratosis pilaris, Photodamage, Melasma

๐Ÿ“‹ Drug Information

Generic Name(s)Adapalene + Clindamycin
Brand NameAcnesol A Nano Gel
ManufacturerGenesis Biotech Inc
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassRetinoid + Antibiotic
Route of AdministrationTopical
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light and heat
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionMinimal systemic absorption; primarily local cutaneous absorption
DistributionNot extensively studied; limited systemic distribution
Protein BindingAdapalene: >95% bound to plasma proteins; Clindamycin: ~60-94% bound
MetabolismAdapalene: Hepatic via CYP2C9 and CYP3A4; Clindamycin: Hepatic via CYP3A4
Half-LifeAdapalene: ~7-12 hours; Clindamycin: ~2-3 hours
ExcretionAdapalene: Biliary; Clindamycin: Renal and biliary
BioavailabilityLow systemic bioavailability due to topical application
Onset of Action2-4 weeks
Peak Plasma TimeNot applicable for topical use
Duration of ActionNot specified; applied once daily

How It Works

Adapalene binds to retinoic acid receptors (RARs) to normalize follicular keratinization; Clindamycin inhibits bacterial protein synthesis by binding to 50S ribosomal subunit

Mechanism Steps

1Adapalene binds to RAR-ฮฒ and RAR-ฮณ receptors in keratinocytes
2Modulates gene expression to normalize follicular keratinization
3Reduces microcomedone formation and comedogenesis

๐Ÿ’ก How to Take aknea c gel

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of aknea c gel

โœ… Common Side Effects

  • Skin dryness
  • Erythema
  • Peeling
  • Burning
  • Stinging
  • Pruritus

๐Ÿšจ Serious Side Effects

  • Pseudomembranous colitis
  • Severe allergic reactions
  • Photosensitivity

โš ๏ธ Rare Side Effects

  • Contact dermatitis
  • Hyperpigmentation
  • Hypopigmentation

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Erythromycin Moderate Increased risk of skin irritation
Benzoyl Peroxide Moderate May cause excessive dryness or irritation
Tetracycline Minor Possible additive effect

๐Ÿšจ Major Interactions

  • Erythromycin
  • Tetracyclines
  • Systemic retinoids
  • Neuromuscular blocking agents

โšก Moderate Interactions

  • Topical corticosteroids
  • Topical benzoyl peroxide
  • Other topical antibiotics

โ„น๏ธ Minor Interactions

  • Cosmetics with drying or abrasive effects

๐Ÿท Alcohol Interaction

No known interaction

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category C

๐Ÿšซ Contraindications

Hypersensitivity to adapalene, clindamycin, or any component; history of regional enteritis, ulcerative colitis, or antibiotic-associated colitis

๐Ÿ“Š Monitoring Parameters

Skin irritation, dryness, peeling; signs of infection; pregnancy status

๐Ÿคฑ Lactation Safety

Caution; not recommended during breastfeeding

๐Ÿ’Š Overdose Management

Excessive topical application may cause severe irritation; treat symptomatically; accidental ingestion may cause gastrointestinal effects; supportive care

โฐ Missed Dose

Apply as soon as remembered; if near next dose, skip missed dose; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

๐Ÿ”— View Profile

โญ User Reviews

Regular Customer Jul 10, 2026

Effective and reliable. Worked as expected.

Verified User Jul 10, 2026

Found this to be a helpful product. Good results.

Verified User Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Verified User Jul 10, 2026

Effective and reliable. Worked as expected.

Happy Patient Jul 10, 2026

Effective and reliable. Worked as expected.

๐Ÿ˜Š Was this information helpful?

Browse Medicines A-Z

Search our extensive medical database alphabetically.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory