ak-60 dry syrup - Ampicillin (125mg) + Cloxacillin (125mg) medicine

AK-60 Dry Syrup - Uses, Price, Side Effects

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๐Ÿญ Bactolac Formulations Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 29, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 29, 2026

What is ak-60 dry syrup used for?

AK-60 Dry Syrup is a combination antibiotic containing Ampicillin (125mg) and Cloxacillin (125mg). It is used to treat bacterial infections such as respiratory tract infections, urinary tract infections, skin infections, and soft tissue infections. Ampicillin works by inhibiting bacterial cell wall synthesis, while Cloxacillin is effective against penicillinase-producing bacteria, making it a broad-spectrum treatment.

  • Generic Name: Ampicillin + Cloxacillin
  • Manufacturer: Bactolac Formulations Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: B
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š ak-60 dry syrup Uses & Benefits

Respiratory tract infections, urinary tract infections, skin and soft tissue infections, bone and joint infections

Off-label uses: Prophylaxis in dental procedures, Endocarditis prophylaxis

๐Ÿ“‹ Drug Information

Generic Name(s)Ampicillin + Cloxacillin
Brand NameAmpoxin 500 Capsule
ManufacturerBactolac Formulations Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassPenicillinase-resistant penicillin combination
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed from the gastrointestinal tract
DistributionDistributed widely in body tissues and fluids, including pleural, peritoneal, and synovial fluids
Protein BindingAmpicillin: 15-25%; Cloxacillin: 90-95%
MetabolismPartially hepatic
Half-LifeAmpicillin: 1-1.5 hours; Cloxacillin: 0.5-1 hour
ExcretionRenal (tubular secretion and glomerular filtration)
BioavailabilityAmpicillin: 50-60%; Cloxacillin: 50-70%
Onset of Action1-2 hours
Peak Plasma Time1-2 hours
Duration of Action6-8 hours

How It Works

Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to cell lysis

Mechanism Steps

1Penetration through bacterial cell wall via porins
2Binding to penicillin-binding proteins (PBPs) on the inner membrane
3Inhibition of transpeptidase activity, preventing cross-linking of peptidoglycan

๐Ÿ’ก How to Take ak-60 dry syrup

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โœ… ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of ak-60 dry syrup

โœ… Common Side Effects

  • Diarrhea
  • Nausea
  • Vomiting
  • Rash
  • Urticaria

๐Ÿšจ Serious Side Effects

  • Anaphylaxis
  • Pseudomembranous colitis
  • Stevens-Johnson syndrome
  • Seizures

โš ๏ธ Rare Side Effects

  • Hemolytic anemia
  • Agranulocytosis
  • Interstitial nephritis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Methotrexate Major Increased methotrexate toxicity
Warfarin Moderate Enhanced anticoagulant effect
Probenecid Moderate Decreased renal excretion of ampicillin and cloxacillin

๐Ÿšจ Major Interactions

  • Methotrexate
  • Warfarin
  • Probenecid

โšก Moderate Interactions

  • Oral contraceptives
  • Allopurinol
  • Chloramphenicol

โ„น๏ธ Minor Interactions

  • Aminoglycosides
  • Tetracyclines

๐Ÿฝ๏ธ Food Interactions

Food may decrease absorption; take on empty stomach

๐Ÿท Alcohol Interaction

No known interaction

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category B

๐Ÿšซ Contraindications

Hypersensitivity to penicillins, cephalosporins, or any component

๐Ÿ“Š Monitoring Parameters

Renal function, hepatic function, complete blood count, signs of hypersensitivity

๐Ÿคฑ Lactation Safety

Excreted in breast milk in low concentrations; generally considered compatible

๐Ÿ’Š Overdose Management

Supportive care; hemodialysis may be considered

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 29, 2026

๐Ÿ”— View Profile

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