Affytericin-B Injection (Amphotericin B 50mg) - Uses, Price, Side Effects
What is affytericin-b injection used for?
Affytericin-B Injection contains Amphotericin B 50mg, an antifungal medication used to treat serious systemic fungal infections like aspergillosis, candidiasis, and cryptococcosis. It works by binding to ergosterol in fungal cell membranes, causing leakage and cell death. It is typically administered intravenously under medical supervision.
- Generic Name: Amphotericin B
- Manufacturer: Affy Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: B
- Prescription Required: Yes
๐ affytericin-b injection Uses & Benefits
Vaginal candidiasis.
Off-label uses: Not commonly used off-label.
๐ Drug Information
| Generic Name(s) | Amphotericin B |
| Brand Name | Amfy V Vaginal Gel |
| Manufacturer | Affy Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Fungal cell membrane active agent |
| Route of Administration | Vaginal (topical). |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Binds to ergosterol in fungal cell membrane, forming pores leading to leakage of ions and cell death.
Mechanism Steps
๐ก How to Take affytericin-b injection
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of affytericin-b injection
โ Common Side Effects
- Vaginal burning
- Itching
- Irritation
๐จ Serious Side Effects
- Severe allergic reaction (rare)
โ ๏ธ Rare Side Effects
- Contact dermatitis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Digoxin | Major | Increased risk of digoxin toxicity |
| Corticosteroids | Moderate | Increased risk of hypokalemia |
| Nephrotoxic drugs (e.g., aminoglycosides) | Major | Increased nephrotoxicity |
๐จ Major Interactions
- Nephrotoxic drugs (e.g., aminoglycosides, cyclosporine)
- Corticosteroids
- Digitalis glycosides
โก Moderate Interactions
- Antineoplastic agents
- Diuretics
- Skeletal muscle relaxants
โน๏ธ Minor Interactions
- Flucytosine
๐ฝ๏ธ Food Interactions
No significant food interactions.
๐ท Alcohol Interaction
No known interaction.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to amphotericin B or any component.
๐ Monitoring Parameters
Clinical response; local irritation.
๐คฑ Lactation Safety
Not absorbed systemically; considered safe during lactation.
๐ Overdose Management
Overdose unlikely due to local application; symptomatic treatment if needed.
โฐ Missed Dose
Apply as soon as remembered; skip if almost time for next dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for affytericin-b injection
View AllAlternative brands with exact same active ingredient (Amphotericin B (50mg)):
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amphotret 50mg injectionBharat Serums & Vaccines Ltd โน238.76 26.3% CHEAPER
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ampholyn 50mg injectionHetero Drugs Ltd โน269.00 17% CHEAPER
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amtericin 50mg injectionVhb Life Sciences Inc โน275.00 15.1% CHEAPER
-
fungizone 50mg injectionAbbott โน295.10 8.9% CHEAPER
-
amphotin 50 mg injectionUnited Biotech Pvt Ltd โน299.00 7.7% CHEAPER
-
mycoflu injectionJolly Healthcare โน326.00 0.6% COSTLIER
-
ambiship injectionFlagship Biotech International โน339.00 4.6% COSTLIER
-
amfocare 50mg injectionDabur India Ltd โน407.63 25.8% COSTLIER
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amfotex 50mg injectionAlkem Laboratories Ltd โน450.00 38.9% COSTLIER
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ampho b 50mg injectionVhb Life Sciences Inc โน452.95 39.8% COSTLIER
Medical Note: Always consult your doctor before switching medications.
โญ User Reviews
Found this to be a helpful product. Good results.
Helpful and effective medicine as per my experience. Always consult a doctor.
Helpful and effective medicine as per my experience. Always consult a doctor.
Helpful and effective medicine as per my experience. Always consult a doctor.
Good quality medicine. Satisfied with the outcome.