AF 200 Tablet (Fluconazole 200 mg): Complete Uses, Dosage, Side Effects, and Safety Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Yellowing of the skin or eyes, dark urine, or pale stools
- Severe abdominal pain, persistent vomiting, or blood in vomit or stool
- A rapidly spreading rash with blisters, mouth sores, or skin peeling
- Swelling of the face, lips, or throat, or difficulty breathing
- Palpitations, fainting, or severe dizziness
- Unusual bruising or bleeding
- Severe headache with confusion, neck stiffness, or sensitivity to light
- Decreased urine output or swelling of the legs
If experiencing severe symptoms, call emergency services immediately.
What is afcon 200mg tablet used for?
This medicine contains Fluconazole 200 mg, an oral antifungal tablet used to treat fungal infections such as vaginal thrush, oral thrush, and serious Candida or Cryptococcus infections. It works by damaging the fungal cell membrane. Take it exactly as prescribed, avoid alcohol, and tell your doctor about all other medicines because it has many interactions.
- Generic Name: Fluconazole
- Manufacturer: AS Lifesciences
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 afcon 200mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा फ्लुकोनाज़ोल 200 मिलीग्राम की एक ओरल एंटीफंगल टैबलेट है, जिसका उपयोग फंगल संक्रमण के इलाज के लिए किया जाता है। इसे योनि में होने वाले फंगल संक्रमण (वजाइनल थ्रश), मुँह और गले के फंगल संक्रमण, और गंभीर कैंडिडा या क्रिप्टोकोकस संक्रमण के लिए दिया जाता है। यह दवा फंगस की कोशिका की दीवार को कमजोर करके उसे मार देती है। यह बैक्टीरिया या वायरस से होने वाले संक्रमण पर असर नहीं करती, इसलिए सर्दी-जुकाम या साधारण बुखार में इसका इस्तेमाल न करें। इस दवा को डॉक्टर के बताए अनुसार ही लें, पूरा कोर्स पूरा करें, और शराब से बचें। अगर आप गर्भवती हैं, स्तनपान करा रही हैं, या कोई और दवा ले रही हैं, तो डॉक्टर को जरूर बताएं।
साइड इफेक्ट्स: इस दवा को ज्यादातर लोग अच्छी तरह सहन करते हैं, लेकिन कुछ लोगों में सिरदर्द, जी मिचलाना, पेट में असहजता, दस्त, अपच, या हल्के दाने हो सकते हैं। ये आमतौर पर हल्के होते हैं और खुद ठीक हो जाते हैं। कभी-कभी गंभीर समस्याएं भी हो सकती हैं, जैसे लिवर को नुकसान, जिसमें आँखों या त्वचा का पीला पड़ना, गहरे रंग का पेशाब, या बहुत ज्यादा थकान दिख सकती है। त्वचा पर फफोले पड़ना, मुँह या गले में सूजन, दिल की धड़कन तेज या अनियमित होना, या बेहोशी जैसी स्थिति में तुरंत डॉक्टर से मिलें। अगर कोई भी असामान्य लक्षण लंबे समय तक बना रहे, तो डॉक्टर को बताएं।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें और अपनी मर्जी से डोज न बदलें। टैबलेट को पानी के साथ पूरा निगलें; इसे खाने के साथ या बिना खाने के लिया जा सकता है, लेकिन खाने के साथ लेने से पेट की तकलीफ कम हो सकती है। अगर कुछ दिनों में आराम लगने लगे तो भी पूरा कोर्स पूरा करें, वरना फंगल संक्रमण फिर लौट सकता है। इस दवा के साथ शराब न पिएं, क्योंकि इससे लिवर पर असर पड़ सकता है। अगर आपको लिवर या किडनी की बीमारी, दिल की धड़कन की समस्या, या पोटैशियम की कमी है, तो डॉक्टर को पहले बताएं। वॉरफेरिन, कुछ डायबिटीज की दवाएं, और कुछ दिल या दौरे की दवाओं के साथ यह दवा गंभीर रूप से क्रिया कर सकती है, इसलिए अपनी सभी दवाओं की सूची डॉक्टर और फार्मासिस्ट को बताएं। गर्भवती होने, गर्भ की योजना बनाने, या स्तनपान कराने की स्थिति में डॉक्टर से सलाह लें।
💊 afcon 200mg tablet Uses & Benefits
[{"condition":"Vaginal candidiasis (vaginal thrush)","description":"This medicine is used as a single oral dose to treat uncomplicated vaginal yeast infection caused by Candida species, relieving itching, discharge, and irritation.","evidence":"Well-established"},{"condition":"Oropharyngeal and oesophageal candidiasis","description":"Used to treat fungal infection of the mouth and throat, and of the food pipe, especially in people with weakened immunity or those using inhaled steroids.","evidence":"Well-established"},{"condition":"Cryptococcal meningitis","description":"Used as part of antifungal therapy for cryptococcal infection of the membranes around the brain and spinal cord, often after initial treatment with another antifungal.","evidence":"Well-established"},{"condition":"Invasive candidiasis and candidaemia","description":"Used to treat serious Candida infections of the blood and internal organs in hospitalised patients, guided by culture and sensitivity results.","evidence":"Well-established"},{"condition":"Prevention of fungal relapse in immunocompromised patients","description":"Prescribed to prevent recurrence of fungal infections in people with HIV, transplant recipients, or those on chemotherapy.","evidence":"Well-established"},{"condition":"Tinea infections (ringworm of skin, groin, and feet)","description":"Sometimes used for stubborn or extensive dermatophyte infections when topical treatment is not enough.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Seborrheic dermatitis","description":"Occasionally used off-label for severe or recurrent seborrheic dermatitis linked to Malassezia yeast.","evidence":"Limited"},{"condition":"Onychomycosis (nail fungus)","description":"Sometimes considered off-label for nail fungal infection, though other antifungals are usually preferred.","evidence":"Limited"}]
Primary treatment for: Fungal infections caused by Candida species and other susceptible fungi.
Also treats: Cryptococcal meningitis, Oropharyngeal candidiasis, Oesophageal candidiasis, Vaginal candidiasis, Invasive candidiasis, Tinea infections
📋 Drug Information
| Generic Name(s) | Fluconazole |
| Brand Name | AF 150 Tablet DT |
| Manufacturer | AS Lifesciences |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Fungal ergosterol synthesis inhibitor |
| Route of Administration | Oral. This medicine is taken by mouth as a tablet and swallowed whole with water |
| Storage | Store this medicine at room temperature, between 15°C and 30°C, in a dry place away from direct sunlight and moisture. Keep it in its original packaging, tightly closed, and out of the reach of children. |
| Shelf Life | The shelf life of this medicine is typically 24 to 36 months from the date of manufacture, depending on the batch. Always check the expiry date printed on the pack and do not use the medicine after that date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine is a triazole antifungal that selectively inhibits the fungal cytochrome P450 enzyme lanosterol 14-alpha-demethylase, which is encoded by the ERG11 gene. This enzyme converts lanosterol to ergosterol, the principal sterol of the fungal cell membrane. When the enzyme is blocked, ergosterol production falls and toxic methylated sterol precursors accumulate in the membrane. The result is a weakened, leaky fungal cell membrane that cannot maintain normal function, so fungal growth is stopped and the organism dies. Because this medicine targets a fungal enzyme that is not present in human cells, it is relatively selective for fungi, although it can still inhibit some human cytochrome P450 enzymes and cause drug interactions.
Mechanism Steps
💡 How to Take afcon 200mg tablet
Strength: This medicine is supplied as an immediate-release oral tablet containing Fluconazole 200 mg.
Dosage Information
| Adult Dosage | The dose of this medicine depends on the type and severity of the fungal infection. For uncomplicated vaginal thrush, a single 150 mg dose is often used, but your doctor may prescribe a different regimen. For oral thrush, doses of 50 to 100 mg once daily for 7 to 14 days are common, while serious infections such as cryptococcal meningitis may need 400 mg once daily or higher, sometimes after an initial loading dose. The dose must be individualized by a qualified clinician based on the indication, age, weight, kidney and liver function, and other medicines you take. Never change the dose or duration on your own. |
| Pediatric Dosage | Pediatric dosing of this medicine is not established from available information for all age groups and indications. When used in children, the dose is calculated by a paediatrician based on body weight and the specific infection, and it should never be decided without medical supervision. Consult a paediatrician for any child who needs this medicine. |
| Elderly Dosage | Older adults can usually take this medicine at the same dose as younger adults, but kidney function often declines with age, so the dose may need to be reduced if kidney tests show reduced clearance. Elderly patients are also more likely to take other medicines that interact with this medicine, so a careful review of all medicines is important. Dose must be individualized by a qualified clinician. |
| Renal Impairment | This medicine is cleared mainly by the kidneys, so the dose must be adjusted in people with reduced kidney function. For single-dose treatment of vaginal thrush, no adjustment is usually needed, but for repeated or long courses, the dose is often reduced or the interval between doses lengthened according to the creatinine clearance. Your doctor will decide the exact adjustment based on your kidney function tests. |
| Hepatic Impairment | This medicine is only minimally metabolised by the liver, so liver disease usually does not require a major dose change. However, because this medicine can rarely cause liver injury, people with existing liver disease should be monitored carefully with liver function tests, and the medicine should be used with caution. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum daily dose of this medicine depends on the infection being treated and is decided by your doctor. Doses up to 400 mg once daily are commonly used for serious infections, and higher doses are sometimes used in hospital settings under close supervision. Never exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of afcon 200mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Amiodarone | Major | |
| Cisapride | Major | |
| Terfenadine | Major | |
| Glibenclamide | Major | |
| Phenytoin | Moderate | |
| Rifampicin | Moderate | |
| Cyclosporine | Moderate | |
| Simvastatin | Moderate | |
| Midazolam | Moderate |
🚨 Major Interactions
- Warfarin and other coumarin anticoagulants
- QT-prolonging drugs such as amiodarone, quinidine, and sotalol
- Cisapride
- Terfenadine and astemizole
- Sulfonylureas such as glibenclamide, glipizide, and tolbutamide
⚡ Moderate Interactions
- Phenytoin
- Rifampicin
- Cyclosporine and tacrolimus
- Statins such as simvastatin and atorvastatin
- Benzodiazepines such as midazolam and triazolam
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Both alcohol and this medicine are handled by the liver, and drinking alcohol may increase the risk of liver injury and worsen side effects such as nausea, dizziness, and drowsiness. If you drink regularly, discuss this with your doctor before starting the medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy or hypersensitivity to fluconazole or other azole antifungals","Concurrent use of cisapride, terfenadine, or astemizole","Concurrent use of medicines that can cause dangerous heart rhythms with this medicine","Pregnancy for minor fungal infections unless the doctor decides the benefit outweighs the risk","Severe liver disease, unless the doctor decides the benefit outweighs the risk","Breastfeeding during long or high-dose treatment without medical advice"]
⚠️ Warnings & Precautions
["Tell your doctor about all medicines, supplements, and herbal products you take, because this medicine interacts with many drugs.","Avoid alcohol during treatment to reduce the risk of liver problems.","Use with caution if you have liver disease, kidney disease, or heart rhythm problems.","Stop the medicine and seek medical help if you develop a spreading rash, blisters, or swelling of the face or throat.","Do not drive or operate machinery if you feel dizzy or drowsy.","Complete the full course prescribed by your doctor, even if you feel better early.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.","Keep all follow-up appointments so your doctor can check your response and monitor for side effects."]
🤱 Lactation Safety
This medicine passes into breast milk in small amounts. Short courses are generally considered acceptable during breastfeeding, but long or high-dose treatment should be discussed with your doctor. Watch the baby for feeding problems, rash, or irritability and report any concerns to your paediatrician.
💊 Overdose Management
Overdose of this medicine can cause nausea, vomiting, abdominal pain, dizziness, and, in severe cases, hallucinations, seizures, or heart rhythm problems. If you suspect an overdose, contact your doctor or a poison control centre immediately and go to the nearest emergency department. Treatment is supportive, with monitoring of vital signs, electrolytes, and heart rhythm. There is no specific antidote, and dialysis may be considered in severe cases.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember, provided there is enough time before your next scheduled dose. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed one. If you are unsure what to do, contact your doctor or pharmacist.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor and do not change the dose on your own. Swallow the tablet whole with a glass of water; it can be taken with or without food, but taking it with food may reduce stomach upset. Complete the full course even if you feel better after a few doses, because stopping early can allow the fungus to return. Avoid alcohol while taking this medicine because both are processed by the liver and alcohol may increase the risk of liver problems. Tell your doctor if you have liver disease, kidney disease, heart rhythm problems, or low potassium or magnesium levels, as dose adjustments or extra monitoring may be needed. This medicine can interact with warfarin, some diabetes medicines, certain heart rhythm medicines, and some seizure medicines, so always share your full medicine list with your doctor and pharmacist. Do not start any new medicine, supplement, or herbal product without checking first. If you are pregnant, planning pregnancy, or breastfeeding, speak to your doctor before taking this medicine. Keep the tablet out of reach of children and store it in its original packaging.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults can take this medicine, but kidney function often declines with age, so the dose may need to be reduced if kidney tests show reduced clearance. Elderly patients are also more likely to take multiple medicines, increasing the chance of interactions. A careful review of all medicines and periodic monitoring of kidney and liver function is recommended.
🤰 Pregnancy Planning (TTC)
If you are trying to conceive or planning a pregnancy, tell your doctor before taking this medicine. High doses or long courses of this medicine have been linked to a small increase in birth defects in some studies, so safer alternatives may be preferred for minor fungal infections. Use effective contraception during treatment if advised by your doctor, and do not start or stop this medicine without medical advice.
🏥 Post-Surgery Considerations
If you are recovering from surgery, tell your surgeon and anaesthetist that you are taking this medicine, because it can interact with some medicines used during and after surgery, including certain painkillers and sedatives. Your doctor will decide whether to continue, pause, or adjust the medicine around the time of surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. This medicine can interact with some medicines used in dentistry, and it may also be relevant if you have oral thrush or a bleeding tendency. Your dentist may coordinate with your doctor if any adjustment is needed.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
There is usually no need to avoid exercise while taking this medicine. However, if you feel dizzy, unusually tired, or have palpitations, avoid strenuous activity and contact your doctor. If you have a fungal skin infection, keep the affected area clean and dry after exercise, and avoid sharing gym towels or equipment.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
Most people can continue their usual work and daily activities while taking this medicine. If you feel dizzy, drowsy, or have a headache, avoid driving or operating heavy machinery until you feel better. If your work involves handling food or close contact with others, maintain good hand hygiene to reduce the spread of fungal infections.
🛑 When to Stop This Medicine
Do not stop this medicine on your own before completing the prescribed course, even if you feel better, because the fungal infection may return. Your doctor may stop the medicine early if you develop a serious side effect such as liver problems, a severe skin reaction, or a heart rhythm problem. If you experience any red-flag symptoms, stop the medicine and seek medical help immediately. Always ask your doctor before stopping or changing the treatment.
📅 Long-Term Use Effects
Long-term use of this medicine is usually reserved for serious fungal infections or for preventing relapse in people with weakened immunity. Prolonged treatment may rarely cause liver enzyme changes, hair thinning, or changes in blood counts, so your doctor may check liver function, kidney function, and blood counts periodically. It can also interact with many medicines over time, so your full medicine list should be reviewed regularly. Do not continue this medicine for longer than prescribed without medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
For localised vaginal or skin fungal infections, topical treatments such as clotrimazole or miconazole may be enough and have fewer systemic side effects.
Evidence: Well-establishedFor mild oral thrush, a topical nystatin rinse may be used instead of systemic antifungals.
Evidence: Well-establishedKeeping skin folds and the genital area clean and dry helps prevent and manage fungal infections alongside medical treatment.
Evidence: Well-establishedImproving blood sugar control reduces the frequency and severity of fungal infections in people with diabetes.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There is no known interaction between this medicine and routine vaccines. However, if you have a weakened immune system and are due for a live vaccine, discuss the timing with your doctor, because the underlying condition and its treatment may affect vaccine safety and response.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C.
❌ DON'T
Do not store in the refrigerator unless the label says so.
✅ DO
Keep the tablets in the original blister pack or container.
❌ DON'T
Do not transfer them to unmarked containers.
✅ DO
Keep away from direct sunlight and moisture.
❌ DON'T
Do not store in the bathroom cabinet.
✅ DO
Keep out of the reach of children and pets.
❌ DON'T
Do not use after the expiry date printed on the pack.
✈️ Traveling with This Medicine
When travelling, carry this medicine in its original packaging with the prescription label clearly visible. Keep a copy of your prescription or a doctor's letter with you, especially for international travel, because antifungal medicines may be checked at customs. Store the tablets in a cool, dry place in your hand luggage, away from direct sunlight and extreme heat. If you are crossing time zones and take this medicine daily, try to keep doses about 24 hours apart; ask your doctor or pharmacist for a simple plan. Do not leave the medicine in a hot car or checked luggage, and keep enough supply for the whole trip plus a few extra days in case of delays.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start to feel better within 1 to 2 days for conditions such as vaginal thrush, but deeper infections can take several days to weeks to improve. Always complete the full course prescribed by your doctor.
A: Yes, this medicine can be taken with or without food. Taking it with a meal may reduce stomach upset.
A: It is best to avoid alcohol during treatment because both alcohol and this medicine are processed by the liver, and combining them may increase the risk of liver problems and side effects.
A: This medicine should be used in pregnancy only when clearly needed and after a discussion with your doctor. For minor fungal infections, safer alternatives are often preferred.
A: If you remember soon after the missed dose, take it as soon as you can. If it is almost time for the next dose, skip the missed dose and continue your regular schedule. Do not take two doses at once.
A: Yes, this medicine interacts with many medicines, including warfarin, some diabetes medicines, certain heart medicines, and some seizure medicines. Always tell your doctor and pharmacist about everything you take.
🤔 Common Patient Concerns
🔄 Substitutes for afcon 200mg tablet
View AllAlternative brands with exact same active ingredient:
-
myconorm 200mg tabletPsychotropics India Ltd ₹7.50 57.9% CHEAPER
-
azecon 200 tabletAgex Laboratories Pvt Ltd ₹11.25 36.8% CHEAPER
-
kryptocan 200mg tabletKryptochem Medicament Pvt. Ltd. ₹11.25 36.8% CHEAPER
-
Flukeen 200mg TabletBiogenius Labs ₹11.25 36.8% CHEAPER
-
Nixican 200 TabletCanixa Life Sciences Pvt ₹11.25 36.8% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any infection.
Fact: This medicine only treats fungal infections. It does not work against bacteria or viruses. - Myth: You can stop this medicine as soon as you feel better.
Fact: Stopping early can allow the fungal infection to return. Complete the full course prescribed by your doctor. - Myth: This medicine is safe to take with all other medicines.
Fact: This medicine interacts with many drugs, including warfarin, some diabetes medicines, and certain heart medicines. Always check with your doctor or pharmacist. - Myth: This medicine is a painkiller.
Fact: This medicine is an antifungal and does not relieve pain or fever directly. - Myth: You can take this medicine for a common cold.
Fact: The common cold is caused by viruses, and this medicine has no effect on viral infections.
🔄 Alternative Options
Generic Alternatives
- Fluconazole 200 mg tablet
Brand Alternatives
- Not established from the available information.