Aelxim-CL 325 Tablet - Uses, Price, Side Effects
What is aelxim-cl 325 tablet used for?
Aelxim-CL 325 Tablet is a combination antibiotic containing Cefixime (200mg) and Clavulanic Acid (125mg). It is used to treat various bacterial infections such as respiratory tract infections, urinary tract infections, and skin infections. Cefixime stops bacterial growth by inhibiting cell wall synthesis, while Clavulanic Acid prevents bacterial resistance by inhibiting beta-lactamase enzymes.
- Generic Name: Cefixime + Clavulanic Acid
- Manufacturer: Allenge India
- Form: Allopathy
- Pregnancy Category: B
- Prescription Required: Yes
๐ aelxim-cl 325 tablet Uses & Benefits
Treatment of respiratory tract infections, urinary tract infections, otitis media, sinusitis, and skin infections caused by susceptible bacteria.
Off-label uses: Uncomplicated gonorrhea, Lyme disease
๐ Drug Information
| Generic Name(s) | Cefixime + Clavulanic Acid |
| Brand Name | Abixim CV 200mg/125mg Tablet |
| Manufacturer | Allenge India |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | ANTI INFECTIVES |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC); protect from moisture and light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Cefixime inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs); Clavulanic Acid inhibits beta-lactamases, preventing degradation of cefixime.
Mechanism Steps
๐ก How to Take aelxim-cl 325 tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of aelxim-cl 325 tablet
โ Common Side Effects
- Diarrhea
- Nausea
- Vomiting
- Abdominal pain
- Headache
- Rash
๐จ Serious Side Effects
- Pseudomembranous colitis
- Severe allergic reactions
- Stevens-Johnson syndrome
- Hepatotoxicity
- Seizures
โ ๏ธ Rare Side Effects
- Hemolytic anemia
- Agranulocytosis
- Interstitial nephritis
- Anaphylaxis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Methotrexate | Moderate | Increased methotrexate toxicity |
| Probenecid | Moderate | Reduced excretion of cefixime |
๐จ Major Interactions
- Warfarin
- Methotrexate
- Probenecid
โก Moderate Interactions
- Oral contraceptives
- Live typhoid vaccine
- BCG vaccine
โน๏ธ Minor Interactions
- Antacids
- H2 blockers
- Iron supplements
๐ฝ๏ธ Food Interactions
No significant interaction; may be taken with or without food.
๐ท Alcohol Interaction
No direct interaction; but alcohol may reduce immune response.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to cephalosporins or clavulanic acid; history of cholestatic jaundice/hepatic dysfunction with amoxicillin-clavulanate.
๐ Monitoring Parameters
Renal function, hepatic function, CBC, signs of superinfection.
๐คฑ Lactation Safety
Excreted in breast milk in small amounts; use with caution.
๐ Overdose Management
Supportive care; hemodialysis may be considered.
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose. Do not double dose.