adipin 10mg tablet

4.5 (14 reviews)

Amlodipine (10mg)

🏭 Sain Medicaments Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 21, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 21, 2026

What is adipin 10mg tablet used for?

Amlokind 5 Tablet (Amlodipine) is used to treat CARDIAC. It contains Amlodipine (10mg), which Inhibits calcium ion influx across cardiac and vascular smooth muscle cells, lea. Always consult your doctor before use. Take as prescribed.

Generic Name: Amlodipine
Manufacturer: Sain Medicaments Pvt Ltd
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 adipin 10mg tablet Uses & Benefits

Hypertension, chronic stable angina, vasospastic angina (Prinzmetal's angina).

Off-label uses: Raynaud's phenomenon, migraine prophylaxis, high-altitude pulmonary edema.

📋 Drug Information

Generic Name(s)	Amlodipine
Brand Name	Amlokind 5 Tablet
Manufacturer	Sain Medicaments Pvt Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	CARDIAC
Action Class	Calcium channel blockers- Dihydropyridines (DHP)
Route of Administration	Oral.
Storage	Store at 20-25°C (68-77°F); protect from light and moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed after oral administration with peak plasma concentrations achieved within 6-12 hours.

DistributionExtensively distributed with a large volume of distribution (about 21 L/kg).

Protein BindingApproximately 93% bound to plasma proteins.

MetabolismExtensively metabolized in the liver via CYP3A4 isoenzyme to inactive metabolites.

Half-Life30-50 hours (terminal elimination half-life).

ExcretionPrimarily excreted as metabolites in urine (about 60%) and feces (20-25%).

Bioavailability64-90% (oral bioavailability).

Onset of ActionGradual onset; antihypertensive effect seen within 2-4 hours.

Peak Plasma Time6-12 hours.

Duration of Action24 hours (once-daily dosing).

How It Works

Inhibits calcium ion influx across cardiac and vascular smooth muscle cells, leading to vasodilation and reduced peripheral vascular resistance.

Mechanism Steps

1Binds to L-type calcium channels in vascular smooth muscle and cardiac myocytes.

2Inhibits calcium ion influx during depolarization.

3Reduces intracellular calcium concentration.

💡 How to Take adipin 10mg tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of adipin 10mg tablet

✅ Common Side Effects

Edema (peripheral)
Dizziness
Flushing
Palpitations
Fatigue
Nausea

🚨 Serious Side Effects

Severe hypotension
Myocardial infarction (rare)
Hepatotoxicity (rare)
Stevens-Johnson syndrome (rare)

⚠️ Rare Side Effects

Gingival hyperplasia
Gynecomastia
Leukopenia
Vasculitis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
CYP3A4 inhibitors	Major	Increased amlodipine exposure, risk of toxicity
CYP3A4 inducers	Major	Decreased amlodipine efficacy
Simvastatin	Major	Increased risk of myopathy/rhabdomyolysis
Grapefruit juice	Moderate	Increased amlodipine levels
Diltiazem	Moderate	Increased amlodipine levels
Clarithromycin	Moderate	Increased amlodipine levels
Antacids	Minor	Slight decrease in amlodipine absorption
Sildenafil	Minor	Additive hypotensive effect

🚨 Major Interactions

CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, ritonavir)
CYP3A4 inducers (e.g., rifampin, carbamazepine)
Simvastatin

⚡ Moderate Interactions

Grapefruit juice
Diltiazem
Clarithromycin

ℹ️ Minor Interactions

Antacids
Sildenafil

🍽️ Food Interactions

Grapefruit juice may increase amlodipine levels.

🍷 Alcohol Interaction

Alcohol may potentiate the hypotensive effect.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to amlodipine or dihydropyridines, severe hypotension, cardiogenic shock.

📊 Monitoring Parameters

Blood pressure, heart rate, peripheral edema, liver function tests.

🤱 Lactation Safety

Excreted in breast milk; caution advised.

💊 Overdose Management

Gastric lavage, activated charcoal, supportive care; calcium gluconate may be beneficial.

⏰ Missed Dose

Take as soon as remembered; if close to next dose, skip missed dose. Do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

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🔄 Substitutes for adipin 10mg tablet

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Alternative brands with exact same active ingredient (Amlodipine (10mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Certified Buyer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Trusted Reviewer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Happy Patient Jul 10, 2026

Found this to be a helpful product. Good results.

Regular Customer Jul 10, 2026