Adcef LB 150mg/45M Spores Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe, persistent diarrhea or bloody stools
- Rash, itching, or swelling of the face, lips, tongue, or throat
- Difficulty breathing or swallowing
- Seizures or convulsions
- Yellowing of the skin or eyes
- Decreased urine output or swelling in the legs
- Unusual bleeding or bruising
- Severe abdominal pain
If experiencing severe symptoms, call emergency services immediately.
What is adcef lb 150mg/45million spores tablet used for?
This medicine is a combination of cefdinir, an antibiotic, and Lactobacillus, a probiotic. It is used to treat bacterial infections while helping to prevent antibiotic-associated diarrhea.
- Generic Name: Cefdinir + Lactobacillus
- Manufacturer: Torrent Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 adcef lb 150mg/45million spores tablet के बारे में (Hindi Summary)
उपयोग: यह दवा सेफडिनिर और लैक्टोबैसिलस का संयोजन है, जिसका उपयोग बैक्टीरियल संक्रमणों के इलाज के लिए किया जाता है। यह श्वसन तंत्र, त्वचा, और मूत्र मार्ग के संक्रमणों में प्रभावी है। लैक्टोबैसिलस आंतों के अच्छे बैक्टीरिया को बनाए रखने में मदद करता है, जिससे एंटीबायोटिक से होने वाले दस्त का खतरा कम होता है।
साइड इफेक्ट्स: आम दुष्प्रभावों में दस्त, जी मिचलाना, पेट दर्द, सिरदर्द और योनि में फंगल संक्रमण शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, गंभीर दस्त, और दौरे पड़ सकते हैं। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खुराक न छोड़ें और कोर्स पूरा करें। पेट खराब होने पर भोजन के साथ लें। पर्याप्त पानी पिएं। एल्युमिनियम या मैग्नीशियम युक्त एंटासिड और आयरन सप्लीमेंट को इस दवा से 2 घंटे पहले या बाद में लें। गुर्दे की बीमारी, कोलाइटिस, या एंटीबायोटिक एलर्जी हो तो डॉक्टर को बताएं।
💊 adcef lb 150mg/45million spores tablet Uses & Benefits
[{"condition":"Community-acquired pneumonia","description":"Used to treat mild to moderate community-acquired pneumonia caused by susceptible bacteria such as Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis.","evidence":"Well-established"},{"condition":"Acute bacterial exacerbation of chronic bronchitis","description":"Prescribed for acute worsening of chronic bronchitis due to susceptible bacteria.","evidence":"Well-established"},{"condition":"Acute maxillary sinusitis","description":"Effective against bacterial sinusitis caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Pharyngitis and tonsillitis","description":"Used for streptococcal pharyngitis and tonsillitis in patients who cannot take penicillin.","evidence":"Well-established"},{"condition":"Uncomplicated skin and skin structure infections","description":"Treats infections such as cellulitis, abscesses, and wound infections caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Urinary tract infections","description":"May be used for uncomplicated urinary tract infections caused by susceptible organisms.","evidence":"Limited"}]
Off-label uses: [{"condition":"Otitis media","description":"Sometimes used off-label for middle ear infections in patients allergic to penicillin, though other agents are preferred.","evidence":"Limited"},{"condition":"Lyme disease","description":"Cefdinir has been studied as an alternative for early Lyme disease, but it is not a first-line treatment.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Respiratory tract infections, Skin infections, Urinary tract infections, Sinusitis, Pharyngitis
📋 Drug Information
| Generic Name(s) | Cefdinir + Lactobacillus |
| Brand Name | Adcef LB Tablet |
| Manufacturer | Torrent Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cephalosporin antibiotic + Probiotic |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Cefdinir, the antibiotic component of this medicine, works by binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall. This binding inhibits the final transpeptidation step of peptidoglycan synthesis, which is essential for bacterial cell wall integrity. As a result, the bacterial cell wall becomes weakened, leading to cell lysis and death. The Lactobacillus component is a probiotic that helps restore and maintain the natural gut flora, which can be disrupted by antibiotic therapy.
Mechanism Steps
💡 How to Take adcef lb 150mg/45million spores tablet
Strength: Each immediate-release tablet contains 150 mg of cefdinir and 45 million spores of Lactobacillus.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 300 mg of cefdinir every 12 hours or 600 mg every 24 hours for 5 to 10 days, depending on the type and severity of infection. For uncomplicated urinary tract infections, a dose of 300 mg every 12 hours for 5 to 10 days may be used. The Lactobacillus component is fixed at 45 million spores per tablet. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may have reduced renal function, which can affect the elimination of cefdinir. Dose adjustment may be necessary based on renal function. No specific dose adjustments are recommended solely based on age, but individualization by a clinician is essential. |
| Renal Impairment | In patients with renal impairment (creatinine clearance <30 mL/min), the dose of cefdinir should be reduced. For adults with creatinine clearance <30 mL/min, the recommended dose is 300 mg once daily. Patients on hemodialysis should receive 300 mg after each dialysis session. Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | No specific dosage adjustment is recommended for patients with hepatic impairment. However, caution is advised, and individualization by a clinician is necessary. |
| Maximum Daily Dose | The maximum recommended daily dose of cefdinir for adults is 600 mg. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of adcef lb 150mg/45million spores tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Aluminum/magnesium antacids | Major | |
| Iron supplements | Major | |
| Probenecid | Moderate | |
| Oral contraceptives | Moderate |
🚨 Major Interactions
- Warfarin
- Aluminum- or magnesium-containing antacids
- Iron supplements
⚡ Moderate Interactions
- Probenecid
- Oral contraceptives
🍷 Alcohol Interaction
Alcohol does not directly interact with cefdinir, but it may worsen gastrointestinal side effects such as nausea and abdominal pain. It is advisable to avoid alcohol during antibiotic treatment to support recovery.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to cefdinir or other cephalosporins","Known serious hypersensitivity to penicillins (cross-reactivity possible)","Use in patients with a history of Clostridioides difficile-associated diarrhea"]
⚠️ Warnings & Precautions
["Serious hypersensitivity reactions, including anaphylaxis, have been reported. Discontinue and seek emergency care if allergic reaction occurs.","Clostridioides difficile-associated diarrhea may occur. If severe diarrhea develops, discontinue and consult a doctor.","Use with caution in patients with renal impairment; dose adjustment may be needed.","Prolonged use may result in overgrowth of non-susceptible organisms, including fungi.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Do not use this medicine to treat viral infections.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding."]
🤱 Lactation Safety
Cefdinir is excreted in human breast milk in low concentrations. It is generally considered safe during breastfeeding, but consult your doctor to weigh the benefits and risks. Monitor the infant for diarrhea or thrush.
💊 Overdose Management
Overdose of this medicine may cause nausea, vomiting, abdominal pain, and diarrhea. In case of overdose, seek immediate medical attention. Treatment is symptomatic and supportive. Hemodialysis may be considered in severe cases, especially in patients with renal impairment.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop the course early, even if you feel better. Take the tablet with or without food, but if it upsets your stomach, take it with a meal. Maintain good hydration. Avoid unnecessary use of antacids containing aluminum or magnesium within 2 hours of taking this medicine, as they can reduce its absorption. Inform your doctor if you have a history of kidney disease, colitis, or allergies to antibiotics. Do not share this medicine with others.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to have reduced renal function, which can affect the elimination of cefdinir. Dose adjustment may be necessary. Monitor for signs of superinfection and renal impairment.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. It is classified as Pregnancy Category B, but use only if clearly needed.
🏥 Post-Surgery Considerations
This medicine may be prescribed to prevent or treat surgical site infections. Follow your surgeon's instructions regarding dosing and duration. Inform your surgeon if you have any allergies.
🦷 Dental Procedures
This medicine may be used for dental infections or prophylaxis in patients allergic to penicillin. Inform your dentist if you are taking this medicine or have any allergies.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
You can continue light to moderate exercise if you feel up to it. However, if you experience dizziness, fatigue, or muscle pain, take rest. Avoid strenuous activities until you have fully recovered.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness in some people. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal daily activities, but take rest if you feel unwell.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor, even if you feel better. Stopping early can lead to recurrence of infection and antibiotic resistance. If you experience severe side effects, contact your doctor immediately for advice.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended unless prescribed for a specific chronic infection. Prolonged use may lead to antibiotic resistance, superinfection, and gut flora imbalance. Regular monitoring of renal and liver function may be needed if used for extended periods.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help maintain gut health during antibiotic therapy, but should be taken at least 2 hours apart from the antibiotic.
Evidence: Well-establishedSome herbs like garlic and echinacea may support immune function, but they are not a substitute for antibiotics.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Antibiotics like cefdinir may reduce the effectiveness of live bacterial vaccines (e.g., typhoid vaccine). Avoid taking live vaccines during and shortly after antibiotic therapy. Inactivated vaccines are not affected.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid exposure to extreme temperatures in checked baggage. Store at room temperature and protect from light and moisture. If crossing time zones, adjust dosing times gradually as advised by your doctor. Check customs regulations for carrying prescription medicines in your destination country.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 2-3 days, but it is important to complete the full course as prescribed.
A: Yes, you can take it with or without food. If it upsets your stomach, take it with a meal.
A: Take it as soon as you remember, but if it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: It is classified as Pregnancy Category B. Consult your doctor before taking it during pregnancy.
A: It is best to avoid alcohol as it may worsen side effects like nausea and abdominal pain.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: Antibiotics can cure viral infections like the common cold.
Fact: Antibiotics only work against bacterial infections. This medicine is not effective for viral illnesses. - Myth: You can stop taking antibiotics once you feel better.
Fact: You must complete the full prescribed course to prevent recurrence and antibiotic resistance. - Myth: Probiotics in antibiotics are unnecessary.
Fact: The Lactobacillus in this medicine helps maintain gut health and may reduce antibiotic-associated diarrhea.
🔄 Alternative Options
Generic Alternatives
- Cefdinir 150 mg + Lactobacillus 45 million spores tablet
Brand Alternatives
- Adcef LB 150mg/45million spores tablet