Actam 500 Injection - Uses, Price, Side Effects
What is actam 500 injection used for?
Actam 500 Injection contains Ceftriaxone 500mg, a third-generation cephalosporin antibiotic. It works by killing bacteria and is used to treat various infections like pneumonia, meningitis, sepsis, and urinary tract infections. It is administered intramuscularly or intravenously as directed by a physician.
- Generic Name: Ceftriaxone
- Manufacturer: Dolvis Bio Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: B
- Prescription Required: Yes
๐ actam 500 injection Uses & Benefits
Lower respiratory tract infections, skin and soft tissue infections, urinary tract infections, pelvic inflammatory disease, bacterial septicemia, bone and joint infections, intra-abdominal infections, meningitis, surgical prophylaxis
Off-label uses: Lyme disease, Syphilis, Gonococcal infections
๐ Drug Information
| Generic Name(s) | Ceftriaxone |
| Brand Name | Accuzon 1g Injection |
| Manufacturer | Dolvis Bio Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cephalosporins: 3 generation |
| Route of Administration | Intramuscular or intravenous |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light; reconstituted solution stable for 24 hours at room temperature or 3 days refrigerated |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), inhibiting transpeptidase activity, and activating autolytic enzymes
Mechanism Steps
๐ก How to Take actam 500 injection
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of actam 500 injection
โ Common Side Effects
- Diarrhea
- Injection site reactions (pain, induration)
- Rash
- Eosinophilia
- Thrombocytosis
๐จ Serious Side Effects
- Severe allergic reactions (anaphylaxis)
- Stevens-Johnson syndrome
- Clostridioides difficile-associated diarrhea
- Hemolytic anemia
- Seizures
โ ๏ธ Rare Side Effects
- Pseudomembranous colitis
- Biliary sludge or pseudolithiasis
- Agranulocytosis
- Interstitial nephritis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Alcohol | Moderate | Increased risk of liver toxicity |
| Loop Diuretics | Moderate | Increased risk of nephrotoxicity |
๐จ Major Interactions
- Warfarin
- Alcohol
- Calcium-containing solutions
โก Moderate Interactions
- Aminoglycosides
- Loop diuretics
- Probenecid
โน๏ธ Minor Interactions
- Oral contraceptives
- BCG vaccine
- Typhoid vaccine
๐ฝ๏ธ Food Interactions
None known
๐ท Alcohol Interaction
Disulfiram-like reaction (flushing, headache, nausea, vomiting) possible
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to ceftriaxone or any cephalosporin; hyperbilirubinemic neonates (especially premature); concomitant use with calcium-containing IV solutions in neonates
๐ Monitoring Parameters
Renal function, hepatic function, CBC, signs of superinfection, bleeding tendencies
๐คฑ Lactation Safety
Excreted in breast milk in low concentrations; generally considered compatible with breastfeeding
๐ Overdose Management
Supportive care; hemodialysis may reduce serum levels
โฐ Missed Dose
Administer as soon as remembered; if near next dose, skip missed dose and resume regular schedule
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for actam 500 injection
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axone 500mg injectionCadila Pharmaceuticals Ltd โน18.28 60.1% CHEAPER
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Trionix 500mg InjectionSonixa Lifecare โน27.74 39.4% CHEAPER
Medical Note: Always consult your doctor before switching medications.