Acnex 10mg Capsule - Uses, Price, Side Effects
What is acnex 10mg capsule used for?
Acnex 10mg Capsule contains Isotretinoin, a retinoid used to treat severe acne that hasn't responded to other treatments. It works by reducing sebum production, preventing clogged pores, and decreasing inflammation. It is typically taken twice daily with food for 15-20 weeks.
- Generic Name: Isotretinoin
- Manufacturer: Torrent Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ acnex 10mg capsule Uses & Benefits
Severe recalcitrant nodular acne, acne vulgaris unresponsive to other therapies.
Off-label uses: Rosacea, hidradenitis suppurativa, psoriasis, skin cancer prevention.
๐ Drug Information
| Generic Name(s) | Isotretinoin |
| Brand Name | Acutret 10 Capsule |
| Manufacturer | Torrent Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | Retinoids- First generation |
| Route of Administration | Oral. |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Reduces sebum production, normalizes follicular keratinization, inhibits Propionibacterium acnes growth, and has anti-inflammatory effects.
Mechanism Steps
๐ก How to Take acnex 10mg capsule
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of acnex 10mg capsule
โ Common Side Effects
- Cheilitis
- Dry skin
- Xerophthalmia
- Epistaxis
- Arthralgia
- Myalgia
- Headache
- Increased triglycerides
๐จ Serious Side Effects
- Pseudotumor cerebri
- Hepatotoxicity
- Pancreatitis
- Depression/suicidal ideation
- Inflammatory bowel disease
- Teratogenicity
โ ๏ธ Rare Side Effects
- Thrombocytopenia
- Agranulocytosis
- Vasculitis
- Hearing impairment
- Osteoporosis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Tetracyclines | Major | Increased risk of pseudotumor cerebri |
| Vitamin A supplements | Major | Additive toxic effects |
| Oral contraceptives | Moderate | Reduced efficacy of contraceptives |
๐จ Major Interactions
- Tetracyclines
- Vitamin A supplements
- Methotrexate
- Oral contraceptives (reduced efficacy)
โก Moderate Interactions
- Phenytoin
- Corticosteroids
- Antifungals (azole)
โน๏ธ Minor Interactions
- Alcohol
- Antacids
๐ฝ๏ธ Food Interactions
High-fat meals increase absorption.
๐ท Alcohol Interaction
May increase risk of hepatotoxicity; avoid concurrent use.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Pregnancy, breastfeeding, hypersensitivity to retinoids, hypervitaminosis A, severe hepatic impairment.
๐ Monitoring Parameters
Liver function tests, serum lipids, pregnancy test (monthly), CBC, renal function.
๐คฑ Lactation Safety
Contraindicated; excreted in breast milk.
๐ Overdose Management
Supportive care; symptoms include headache, vomiting, facial flushing, cheilitis, abdominal pain. No specific antidote.
โฐ Missed Dose
Take as soon as remembered unless near next dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for acnex 10mg capsule
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isoret 10mg capsuleSantiago Lifesciences Pvt Ltd โน70.00 37.7% CHEAPER
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tetilin 10mg capsuleLincoln Pharmaceuticals Ltd โน89.00 20.8% CHEAPER
Medical Note: Always consult your doctor before switching medications.