acnerus t 0.05% cream - Tretinoin (0.05% w/w) medicine

Acnerus T 0.05% Cream - Uses, Price, Side Effects

4.2 (13 reviews)

Tretinoin (0.05% w/w)

🏭 Cyrus Remedies 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 23, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 23, 2026

What is acnerus t 0.05% cream used for?

Acnerus T 0.05% Cream contains Tretinoin, a retinoid used to treat acne by promoting skin cell turnover and preventing clogged pores. It reduces acne lesions, blackheads, and whiteheads, and helps improve skin texture. Apply a thin layer at night as directed.

Generic Name: Tretinoin
Manufacturer: Cyrus Remedies
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 acnerus t 0.05% cream Uses & Benefits

Acne vulgaris; photoaging (off-label); fine wrinkles (off-label).

Off-label uses: Photoaging, Fine wrinkles, Melasma

📋 Drug Information

Generic Name(s)	Tretinoin
Brand Name	A-Ret 0.05% Gel
Manufacturer	Cyrus Remedies
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	DERMA
Action Class	Retinoids- First generation
Route of Administration	Topical
Storage	Store at 20-25°C (68-77°F); protect from light and heat.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionMinimal percutaneous absorption; systemic absorption is low when applied topically.

DistributionDistributes locally in the skin; systemic distribution is negligible.

Protein Binding>95% bound to plasma proteins (mainly albumin) if absorbed.

MetabolismMetabolized in the liver via CYP450 enzymes, primarily CYP2C8 and CYP2C9.

Half-LifeApproximately 0.5-2 hours for systemic tretinoin; topical application has minimal systemic half-life

ExcretionExcreted in urine and feces as metabolites.

BioavailabilityLow systemic bioavailability due to minimal percutaneous absorption.

Onset of Action2-3 weeks for visible improvement in acne.

Peak Plasma TimeNot applicable for topical use; systemic peak not relevant.

Duration of ActionEffects persist with continued use; improvement may take up to 12 weeks.

How It Works

Binds to retinoic acid receptors (RARs) in the skin, normalizing follicular keratinization and reducing comedone formation.

Mechanism Steps

1Binds to retinoic acid receptors (RARs) in keratinocytes.

2Modulates gene expression involved in cell differentiation and proliferation.

3Normalizes follicular keratinization, reducing comedone formation.

💡 How to Take acnerus t 0.05% cream

Follow your doctor's prescription exactly.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ✅

⚠️ Side Effects of acnerus t 0.05% cream

✅ Common Side Effects

Skin redness
Peeling
Dryness
Stinging
Burning sensation

🚨 Serious Side Effects

Severe skin irritation
Allergic reaction
Photosensitivity

⚠️ Rare Side Effects

Hyperpigmentation
Hypopigmentation
Scarring

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Benzoyl Peroxide	Moderate	Increased skin irritation
Salicylic Acid	Moderate	Increased skin dryness and peeling
Topical Corticosteroids	Moderate	Reduced efficacy of tretinoin
Sulfur	Moderate	Increased skin irritation
Resorcinol	Moderate	Increased skin irritation

🚨 Major Interactions

Other topical retinoids
Benzoyl peroxide (concomitant use may cause irritation)

⚡ Moderate Interactions

Topical corticosteroids
Topical resorcinol
Topical sulfur

ℹ️ Minor Interactions

Cosmetics with drying or abrasive effects

🍽️ Food Interactions

No significant food interactions.

🍷 Alcohol Interaction

No known interaction.

🛡️ Safety & Warnings

Liver

Low

Kidney

Low

Heart

Low

Pregnancy

Category A

🚫 Contraindications

Hypersensitivity to tretinoin or any component; pregnancy; breastfeeding; eczema; sunburn.

📊 Monitoring Parameters

Monitor for skin irritation, redness, peeling; pregnancy test if applicable.

🤱 Lactation Safety

Safety not established; avoid use during breastfeeding.

💊 Overdose Management

Overdose unlikely with topical use; if ingested, treat symptomatically.

⏰ Missed Dose

Apply as soon as remembered; if near next dose, skip missed dose and resume regular schedule.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 23, 2026

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🔄 Substitutes for acnerus t 0.05% cream

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Alternative brands with exact same active ingredient (Tretinoin (0.05% w/w)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Trusted Reviewer Jul 10, 2026

Found this to be a helpful product. Good results.

Happy Patient Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Certified Buyer Jul 10, 2026

Effective and reliable. Worked as expected.

Verified User Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.