Acitros 25mg Capsule - Uses, Price, Side Effects
What is acitros 25mg capsule used for?
Acitros 25mg Capsule contains Acitretin, a retinoid used to treat severe psoriasis in adults. It works by slowing skin cell growth and reducing inflammation. It is taken with food and requires regular monitoring of liver function and pregnancy tests due to high risk of birth defects.
- Generic Name: Acitretin
- Manufacturer: Chemo Healthcare Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ acitros 25mg capsule Uses & Benefits
Severe psoriasis (plaque, pustular, erythrodermic), disorders of keratinization (e.g., ichthyosis, Darier disease).
Off-label uses: Prevention of skin cancers (non-melanoma), lichen planus, lupus erythematosus.
๐ Drug Information
| Generic Name(s) | Acitretin |
| Brand Name | Acrotac 25mg Capsule |
| Manufacturer | Chemo Healthcare Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | Retinoids- Second generation |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Binds to retinoic acid receptors (RARs) and retinoid X receptors (RXRs), modulating gene transcription involved in cell differentiation, proliferation, and keratinization.
Mechanism Steps
๐ก How to Take acitros 25mg capsule
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of acitros 25mg capsule
โ Common Side Effects
- Cheilitis
- Dry skin
- Alopecia
- Hyperlipidemia
- Elevated LFTs
- Rhinorrhea
- Xerophthalmia
๐จ Serious Side Effects
- Hepatotoxicity
- Pseudotumor cerebri
- Pancreatitis
- Severe depression/suicidal ideation
- Teratogenicity
โ ๏ธ Rare Side Effects
- Osteoporosis
- Premature epiphyseal closure
- Thrombocytopenia
- Photosensitivity
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Methotrexate | Major | Increased risk of hepatotoxicity |
| Tetracyclines | Major | Increased risk of pseudotumor cerebri |
| Vitamin A supplements | Major | Additive toxicity |
| Alcohol | Moderate | Increased risk of liver damage |
๐จ Major Interactions
- Methotrexate
- Tetracyclines
- Vitamin A supplements
- Oral contraceptives (reduced efficacy)
โก Moderate Interactions
- Phenytoin
- Warfarin
- Corticosteroids
โน๏ธ Minor Interactions
- Alcohol
- Grapefruit juice
๐ฝ๏ธ Food Interactions
High-fat meals increase absorption.
๐ท Alcohol Interaction
May increase hepatotoxicity risk; avoid concurrent use.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Pregnancy, breastfeeding, severe hepatic/renal impairment, hypersensitivity to retinoids, concomitant use with methotrexate or tetracyclines.
๐ Monitoring Parameters
LFTs, serum lipids, renal function, pregnancy test (monthly), blood glucose, CBC.
๐คฑ Lactation Safety
Contraindicated; excreted in milk.
๐ Overdose Management
Supportive care; monitor for signs of hypervitaminosis A (headache, vomiting, skin peeling).
โฐ Missed Dose
Take as soon as remembered unless near next dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for acitros 25mg capsule
View AllAlternative brands with exact same active ingredient (Acitretin (25mg)):
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sentrane 25mg capsuleTaj Pharma India Ltd โน386.25 56.4% CHEAPER
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glacitret 25mg capsuleTripada Biotec Pvt Ltd โน464.06 47.6% CHEAPER
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acitinext 25 capsuleEthinext Pharma โน506.25 42.8% CHEAPER
-
psotretin 25mg tabletNuper therapeutics โน515.63 41.7% CHEAPER
-
a tret 25mg capsuleKaizen Pharmaceuticals Pvt Ltd โน553.13 37.5% CHEAPER
-
acitrin 25mg capsuleIpca Laboratories Ltd โน576.26 34.9% CHEAPER
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acetroin 25mg tabletNidus Pharma Pvt Ltd โน585.94 33.8% CHEAPER
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tretoact 25 capsuleRockmed Pharma Pvt. Ltd. โน595.31 32.7% CHEAPER
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zoratame 25mg capsuleCipla Ltd โน600.00 32.2% CHEAPER
-
acetec 25mg capsuleDr Reddy's Laboratories Ltd โน647.81 26.8% CHEAPER
Medical Note: Always consult your doctor before switching medications.