acevas 10 tablet - Rosuvastatin (10mg) medicine

Acevas 10 Tablet - Uses, Price, Side Effects

4.5 (15 reviews)

Rosuvastatin (10mg)

🏭 Samson Laboratories Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 22, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 22, 2026

What is acevas 10 tablet used for?

Acevas 10 Tablet contains Rosuvastatin 10mg, a statin used to lower high cholesterol and triglyceride levels. It works by blocking an enzyme that produces cholesterol in the liver, reducing the risk of heart attack and stroke. It is prescribed for adults with high cholesterol or those at risk of cardiovascular disease.

Generic Name: Rosuvastatin
Manufacturer: Samson Laboratories Pvt Ltd
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 acevas 10 tablet Uses & Benefits

Hypercholesterolemia (primary and mixed dyslipidemia), homozygous familial hypercholesterolemia, prevention of cardiovascular events in patients with risk factors.

Off-label uses: Chronic kidney disease, non-alcoholic fatty liver disease, post-transplant hyperlipidemia.

📋 Drug Information

Generic Name(s)	Rosuvastatin
Brand Name	Arvast 10 Tablet
Manufacturer	Samson Laboratories Pvt Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	CARDIAC
Action Class	HMG CoA inhibitors (statins)
Route of Administration	Oral.
Storage	Store at 20-25°C (68-77°F); protect from light and moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionAbsorbed rapidly after oral administration; peak plasma concentrations achieved in 3-5 hours. Absolute bioavailability is approximately 20%.

DistributionDistributed extensively to extravascular sites; volume of distribution is about 134 L. Highly bound to plasma proteins.

Protein BindingApproximately 88% bound to plasma proteins, mainly albumin.

MetabolismMinimal metabolism; approximately 10% is metabolized by CYP2C9 to N-desmethyl rosuvastatin, which has 1/6 to 1/2 the activity of the parent compound.

Half-LifeApproximately 19 hours (range 13-20 hours).

ExcretionPrimarily excreted in feces (90%) as unchanged drug and metabolites; renal excretion accounts for about 10%.

BioavailabilityApproximately 20%.

Onset of ActionOnset of lipid-lowering effect occurs within 1 week, with maximal effect seen after 4 weeks.

Peak Plasma Time3-5 hours.

Duration of ActionDuration of action is approximately 24 hours, allowing once-daily dosing.

How It Works

Competitive inhibitor of HMG-CoA reductase, the rate-limiting enzyme in cholesterol biosynthesis, leading to reduced intracellular cholesterol levels and increased LDL receptor expression.

Mechanism Steps

1Rosuvastatin competitively inhibits HMG-CoA reductase, the enzyme that converts HMG-CoA to mevalonate.

2This reduces intracellular cholesterol synthesis in the liver.

3Decreased intracellular cholesterol leads to upregulation of LDL receptors on hepatocyte surface.

💡 How to Take acevas 10 tablet

Follow your doctor's prescription exactly.

Dosage Timeline

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

⚠️ Side Effects of acevas 10 tablet

✅ Common Side Effects

Myalgia
Headache
Nausea
Diarrhea
Constipation
Abdominal pain
Asthenia

🚨 Serious Side Effects

Rhabdomyolysis
Myopathy
Hepatotoxicity
Acute renal failure (secondary to rhabdomyolysis)
Hypersensitivity reactions

⚠️ Rare Side Effects

Peripheral neuropathy
Memory loss
Gynecomastia
Interstitial lung disease
Tendon rupture

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Warfarin	Major	Increased bleeding risk
Gemfibrozil	Major	Increased risk of myopathy/rhabdomyolysis
Cyclosporine	Major	Increased rosuvastatin levels
Erythromycin	Moderate	Increased rosuvastatin exposure
Antacids	Moderate	Reduced rosuvastatin absorption

🚨 Major Interactions

Cyclosporine
Gemfibrozil
Warfarin
Fibrates
Niacin (lipid-lowering doses)

⚡ Moderate Interactions

Erythromycin
Itraconazole
Ketoconazole
Protease inhibitors
Amiodarone
Verapamil

ℹ️ Minor Interactions

Digoxin
Oral contraceptives
Antacids (aluminum/magnesium)
Fenofibrate

🍽️ Food Interactions

Grapefruit juice may increase rosuvastatin exposure; avoid large quantities. Food does not affect absorption.

🍷 Alcohol Interaction

Alcohol may increase risk of hepatotoxicity; limit consumption.

🛡️ Safety & Warnings

Liver

Moderate

Kidney

Low

Heart

Low

Pregnancy

Category A

🚫 Contraindications

Active liver disease, unexplained persistent elevations of serum transaminases, pregnancy, lactation, hypersensitivity to rosuvastatin.

📊 Monitoring Parameters

Lipid profile, liver function tests (ALT, AST) at baseline and periodically, creatine kinase if muscle symptoms occur.

🤱 Lactation Safety

Not recommended; excreted in breast milk in animal studies.

💊 Overdose Management

No specific antidote; symptomatic and supportive care; monitor liver function and CK levels.

⏰ Missed Dose

Take as soon as remembered; if close to next dose, skip missed dose; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

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🔄 Substitutes for acevas 10 tablet

View All

Alternative brands with exact same active ingredient (Rosuvastatin (10mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Verified User Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Happy Patient Jul 10, 2026

Effective and reliable. Worked as expected.

Trusted Reviewer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.