aceherp 400 tablet - Uses, Price, Side Effects & Substitutes
What is aceherp 400 tablet used for?
Acivir 400 DT Tablet (Acyclovir) is used to treat ANTI INFECTIVES. It contains Acyclovir (400mg), which Acyclovir is converted to acyclovir monophosphate by viral thymidine kinase, the. Always consult your doctor before use. Take as prescribed.
- Generic Name: Acyclovir
- Manufacturer: Pinarc Life Sciences
- Form: Allopathy
- Pregnancy Category: B
- Prescription Required: Yes
๐ aceherp 400 tablet Uses & Benefits
Herpes simplex infections (genital, oral, encephalitis), varicella-zoster (chickenpox, shingles).
Off-label uses: Herpes simplex prophylaxis in immunocompromised, EBV infection
๐ Drug Information
| Generic Name(s) | Acyclovir |
| Brand Name | Acivir 400 DT Tablet |
| Manufacturer | Pinarc Life Sciences |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Antiviral (Non-HIV) drugs |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Acyclovir is converted to acyclovir monophosphate by viral thymidine kinase, then to triphosphate by cellular kinases, which inhibits viral DNA polymerase and incorporates into viral DNA, causing chain termination.
Mechanism Steps
๐ก How to Take aceherp 400 tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of aceherp 400 tablet
โ Common Side Effects
- Nausea
- Diarrhea
- Headache
- Dizziness
- Fatigue
๐จ Serious Side Effects
- Acute renal failure
- Neurotoxicity (confusion, hallucinations, seizures)
- Thrombotic thrombocytopenic purpura/hemolytic uremic syndrome (TTP/HUS)
โ ๏ธ Rare Side Effects
- Hepatitis
- Stevens-Johnson syndrome
- Anaphylaxis
- Leukopenia
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Probenecid | Major | Reduced renal clearance of acyclovir, increased plasma levels and toxicity risk. |
| Cimetidine | Major | Increased acyclovir AUC and half-life. |
| Mycophenolate mofetil | Major | Increased plasma levels of both drugs; monitor for toxicity. |
| Tenofovir | Moderate | Additive nephrotoxicity risk. |
| Aminoglycosides | Moderate | Increased risk of nephrotoxicity. |
| Cyclosporine | Moderate | Increased nephrotoxicity risk. |
| Tacrolimus | Moderate | Increased nephrotoxicity risk. |
| Zidovudine | Minor | Possible increased drowsiness. |
| Interferon | Minor | Possible additive antiviral effect. |
๐จ Major Interactions
- Probenecid
- Cimetidine
- Mycophenolate mofetil
โก Moderate Interactions
- Tenofovir
- Aminoglycosides
- Cyclosporine
- Tacrolimus
โน๏ธ Minor Interactions
- Zidovudine
- Interferon
๐ฝ๏ธ Food Interactions
No significant food interactions; may be taken with or without food.
๐ท Alcohol Interaction
No known interaction; however, alcohol may exacerbate side effects like dizziness.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to acyclovir or valacyclovir.
๐ Monitoring Parameters
Renal function (especially in elderly or high-dose therapy); hydration status.
๐คฑ Lactation Safety
Caution; acyclovir is excreted in breast milk but considered compatible with breastfeeding.
๐ Overdose Management
Supportive care; hemodialysis may enhance elimination.
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose. Do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for aceherp 400 tablet
View AllAlternative brands with exact same active ingredient (Acyclovir (400mg)):
-
norbita 400mg tabletConcept Pharmaceuticals Ltd โน11.72 89.2% CHEAPER
-
zenclovir 400mg tabletZenlabs Ethica Ltd โน42.19 61.1% CHEAPER
-
aciherpin 400mg tabletAGIO Pharmaceuticals Ltd โน45.83 57.8% CHEAPER
-
okavir 400mg tabletCipla Ltd โน46.88 56.8% CHEAPER
-
docvir 400mg tablet dtSwiss Pharma Pvt Ltd โน51.00 53% CHEAPER
-
bivir tablet dtPrayas Pharmaceuticals โน56.25 48.2% CHEAPER
-
aclovir 400mg tablet dtInd Swift Laboratories Ltd โน61.90 42.9% CHEAPER
-
aciclovir 400 tabletCare Formulation Labs Pvt Ltd โน63.21 41.7% CHEAPER
-
viroglin 400mg tabletNilrise Pharmaceuticals Pvt Ltd โน64.50 40.6% CHEAPER
-
herpesafe 400mg tablet dtAlkem Laboratories Ltd โน65.63 39.5% CHEAPER
Medical Note: Always consult your doctor before switching medications.