Abactum CV 500mg/125mg Tablet - Uses, Price, Side Effects
What is abactum cv 500mg/125mg tablet used for?
Abactum CV 500mg/125mg Tablet is a combination antibiotic containing Cefuroxime (a cephalosporin) and Clavulanic Acid (a beta-lactamase inhibitor). It is used to treat various bacterial infections such as respiratory tract infections, urinary tract infections, skin infections, and more. Cefuroxime kills bacteria by inhibiting cell wall synthesis, while Clavulanic Acid prevents bacterial resistance by inhibiting beta-lactamase enzymes. This tablet is typically taken twice daily with or without food.
- Generic Name: Cefuroxime + Clavulanic Acid
- Manufacturer: Abaris Healthcare
- Form: Allopathy
- Pregnancy Category: B
- Prescription Required: Yes
๐ abactum cv 500mg/125mg tablet Uses & Benefits
Upper and lower respiratory tract infections, urinary tract infections, skin and soft tissue infections, otitis media, sinusitis, bone and joint infections.
Off-label uses: Lyme disease, gonorrhea, surgical prophylaxis (oral form not typically used).
๐ Drug Information
| Generic Name(s) | Cefuroxime + Clavulanic Acid |
| Brand Name | Augxetil CV 500 Tablet |
| Manufacturer | Abaris Healthcare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cephalosporin antibiotic + Beta-lactamase inhibitor |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC); protect from moisture and light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Cefuroxime inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs); Clavulanic acid irreversibly inhibits beta-lactamases, preventing degradation of cefuroxime.
Mechanism Steps
๐ก How to Take abactum cv 500mg/125mg tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of abactum cv 500mg/125mg tablet
โ Common Side Effects
- Diarrhea
- Nausea
- Vomiting
- Rash
- Injection site pain (if IV)
๐จ Serious Side Effects
- Severe allergic reactions
- Clostridioides difficile colitis
- Seizures
- Stevens-Johnson syndrome
โ ๏ธ Rare Side Effects
- Hemolytic anemia
- Interstitial nephritis
- Hepatitis
- Agranulocytosis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Probenecid | Moderate | Reduced elimination of cefuroxime |
| Oral Contraceptives | Minor | Reduced efficacy of contraceptives |
๐จ Major Interactions
- Warfarin
- Methotrexate
- Probenecid
- Live vaccines
โก Moderate Interactions
- Oral contraceptives
- Loop diuretics
- Aminoglycosides
โน๏ธ Minor Interactions
- Antacids
- H2 receptor antagonists
๐ฝ๏ธ Food Interactions
Food increases absorption; take with food to enhance bioavailability.
๐ท Alcohol Interaction
No direct interaction, but alcohol may increase side effects like dizziness.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to cephalosporins or beta-lactamase inhibitors; history of anaphylaxis to penicillins.
๐ Monitoring Parameters
Renal function, liver function, CBC, signs of superinfection or allergic reactions.
๐คฑ Lactation Safety
Excreted in breast milk in small amounts; use with caution.
๐ Overdose Management
Supportive care; hemodialysis may enhance elimination.
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose. Do not double dose.
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Found this to be a helpful product. Good results.
Effective and reliable. Worked as expected.
Helpful and effective medicine as per my experience. Always consult a doctor.
Good quality medicine. Satisfied with the outcome.
This medicine was effective for me. I followed the doctor's advice.