aarticef 500mg injection allopathy (Ceftriaxone (500mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India
aarticef 500mg injection allopathy (Ceftriaxone (500mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India manufactured by Alpic Remedies Ltd. Contains Ceftriaxone (500mg).

aarticef 500mg injection - Uses, Price, Side Effects & Substitutes

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Ceftriaxone (500mg) (Click to see all medicines with same salt)
🏭 Alpic Remedies Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Jun 21, 2026
Medically Reviewed
By SaathiMed Expert Medical Panel

What is aarticef 500mg injection used for?

Accuzon 1g Injection (Ceftriaxone) is used to treat Lower respiratory tract infections. It contains Ceftriaxone (500mg), which Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Ceftriaxone
  • Manufacturer: Alpic Remedies Ltd
  • Medicine Form: Allopathy
  • Pregnancy Category: B

🇮🇳 aarticef 500mg injection के बारे में संक्षिप्त जानकारी (Hindi Summary)

aarticef 500mg injection का उपयोग मुख्य रूप से anti infectives और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Ceftriaxone (500mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।

मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

📋 Drug Information

Generic Name(s)Ceftriaxone
Brand NameAccuzon 1g Injection
ManufacturerAlpic Remedies Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassCephalosporins: 3 generation
Route of AdministrationIntramuscular or intravenous
StorageStore at 20-25°C (68-77°F); protect from light; reconstituted solution stable for 24 hours at room temperature or 3 days refrigerated
Shelf LifeAs per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionIntramuscular administration: well absorbed; intravenous administration: immediate
DistributionWidely distributed into body tissues and fluids, including cerebrospinal fluid (inflamed meninges), bile, and pleural fluid
Protein Binding85-95%
MetabolismNot significantly metabolized; undergoes enterohepatic recirculation
Half-Life5.8-8.7 hours
ExcretionPrimarily renal (33-67%) and biliary (up to 40%)
Bioavailability100% (IV); ~100% (IM)
Onset of ActionRapid (within 30 minutes IV)
Peak Plasma TimeIM: 2-3 hours; IV: end of infusion
Duration of ActionApproximately 24 hours

Pharmacodynamics

Mechanism of ActionInhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), inhibiting transpeptidase activity, and activating autolytic enzymes
Target ReceptorPenicillin-binding proteins (PBPs)
Pharmacodynamic EffectsBactericidal activity against susceptible gram-positive and gram-negative bacteria

💡 How and when to take aarticef 500mg injection?

Follow your doctor's prescription exactly.

  • ✅ Take exactly as prescribed by your doctor.
  • ✅ Do not exceed the recommended dose
  • ✅ Complete the full course of medication
  • ✅ Store at 20-25°C (68-77°F); protect from light; reconstituted solution stable for 24 hours at room temperature or 3 days refrigerated

⚙️ How aarticef 500mg injection Works

Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), inhibiting transpeptidase activity, and activating autolytic enzymes

1 Binds to penicillin-binding proteins (PBPs) on bacterial cell wall
⬇️
2 Inhibits transpeptidase enzyme, preventing cross-linking of peptidoglycan
⬇️
3 Activates autolytic enzymes (autolysins) in bacterial cell wall
⬇️
4 Results in cell wall weakening and lysis

💊 aarticef 500mg injection Uses in Hindi (Ke Fayde), Benefits & Indications

Lower respiratory tract infections, skin and soft tissue infections, urinary tract infections, pelvic inflammatory disease, bacterial septicemia, bone and joint infections, intra-abdominal infections, meningitis, surgical prophylaxis

Off-label uses: Lyme disease, Syphilis, Gonococcal infections

⚠️ What are the side effects of aarticef 500mg injection?

✅ Common Side Effects

  • Diarrhea
  • Injection site reactions (pain, induration)
  • Rash
  • Eosinophilia
  • Thrombocytosis

🚨 Serious Side Effects

  • Severe allergic reactions (anaphylaxis)
  • Stevens-Johnson syndrome
  • Clostridioides difficile-associated diarrhea
  • Hemolytic anemia
  • Seizures

⚠️ Rare Side Effects

  • Pseudomembranous colitis
  • Biliary sludge or pseudolithiasis
  • Agranulocytosis
  • Interstitial nephritis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug Severity Effect
Warfarin Major Increased bleeding risk
Alcohol Major Disulfiram-like reaction
Calcium-containing solutions Major Precipitation risk, especially in neonates
Aminoglycosides Moderate Increased nephrotoxicity risk
Loop diuretics Moderate Increased nephrotoxicity risk
Probenecid Moderate Decreased ceftriaxone excretion
Oral contraceptives Minor Reduced contraceptive efficacy
BCG vaccine Minor Reduced vaccine efficacy
Typhoid vaccine Minor Reduced vaccine efficacy

🚨 Major Interactions

  • Warfarin
  • Alcohol
  • Calcium-containing solutions

⚡ Moderate Interactions

  • Aminoglycosides
  • Loop diuretics
  • Probenecid

ℹ️ Minor Interactions

  • Oral contraceptives
  • BCG vaccine
  • Typhoid vaccine

🍽️ Food Interactions

None known

🍷 Alcohol Interaction

Disulfiram-like reaction (flushing, headache, nausea, vomiting) possible

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to ceftriaxone or any cephalosporin; hyperbilirubinemic neonates (especially premature); concomitant use with calcium-containing IV solutions in neonates

📊 Monitoring Parameters

Renal function, hepatic function, CBC, signs of superinfection, bleeding tendencies

🤱 Lactation Safety

Excreted in breast milk in low concentrations; generally considered compatible with breastfeeding

💊 Overdose Management

Supportive care; hemodialysis may reduce serum levels

⏰ Missed Dose

Administer as soon as remembered; if near next dose, skip missed dose and resume regular schedule

🛑 Myths vs. Facts about aarticef 500mg injection

  • Myth: Generic substitutes of aarticef 500mg injection are less effective.
    Fact: Approved generic medicines contain the exact same active ingredients (Ceftriaxone (500mg)) and are just as safe and effective as the branded version.
  • Myth: Taking a double dose will cure my symptoms faster.
    Fact: Taking more than the prescribed dose of aarticef 500mg injection can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage.
  • Myth: This medicine is 100% safe for everyone.
    Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.

💬 Real Patient Experiences (Astitva)

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