a zole 400mg tablet - Albendazole (400mg) medicine

A Zole 400mg Tablet - Uses, Price, Side Effects

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๐Ÿญ Elegant Drugs Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 26, 2026
โš ๏ธ Hepatotoxicity Risk ๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 26, 2026

What is a zole 400mg tablet used for?

A Zole 400mg Tablet contains Albendazole, an antiparasitic medication used to treat infections caused by worms such as hookworm, roundworm, and tapeworm. It works by preventing the worms from absorbing sugar, causing them to lose energy and die. It is also used for neurocysticercosis and hydatid disease.

  • Generic Name: Albendazole
  • Manufacturer: Elegant Drugs Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š a zole 400mg tablet Uses & Benefits

Hydatid disease (Echinococcus granulosus), Neurocysticercosis (Taenia solium), Ascariasis, Hookworm infection, Pinworm infection, Trichuriasis, Strongyloidiasis

Off-label uses: Cutaneous larva migrans, Capillariasis, Gnathostomiasis, Microsporidiosis

๐Ÿ“‹ Drug Information

Generic Name(s)Albendazole
Brand NameAlbenza
ManufacturerElegant Drugs Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassAntiprotozoal agents
Route of AdministrationOral
StorageStore at 20-25ยฐC (68-77ยฐF); protect from moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionPoorly absorbed orally; absorption enhanced with fatty meal
DistributionWidely distributed; penetrates into cysts and CSF
Protein Binding70%
MetabolismHepatic, primarily via CYP3A4 to active metabolite albendazole sulfoxide
Half-Life8-12 hours (albendazole sulfoxide)
ExcretionRenal (less than 1% unchanged) and biliary
BioavailabilityVariable, increased with fatty meal (up to 5-fold)
Onset of ActionVariable; depends on parasite
Peak Plasma Time2-4 hours (albendazole sulfoxide)
Duration of Action12-24 hours

How It Works

Binds to beta-tubulin, inhibits microtubule polymerization, impairs glucose uptake and energy metabolism in susceptible parasites

Mechanism Steps

1Albendazole is metabolized to albendazole sulfoxide by CYP3A4
2Albendazole sulfoxide binds to beta-tubulin in parasite cells
3Inhibits microtubule polymerization

๐Ÿ’ก How to Take a zole 400mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of a zole 400mg tablet

โœ… Common Side Effects

  • Headache
  • Nausea
  • Vomiting
  • Abdominal pain
  • Dizziness
  • Reversible alopecia

๐Ÿšจ Serious Side Effects

  • Hepatotoxicity
  • Bone marrow suppression (agranulocytosis, pancytopenia)
  • Stevens-Johnson syndrome

โš ๏ธ Rare Side Effects

  • Acute renal failure
  • Allergic reactions
  • Seizures

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Cimetidine Moderate Increased albendazole levels
Theophylline Moderate Increased theophylline levels
Dexamethasone Moderate Decreased albendazole efficacy

๐Ÿšจ Major Interactions

  • Cimetidine
  • Praziquantel
  • Theophylline

โšก Moderate Interactions

  • Carbamazepine
  • Phenytoin
  • Ritonavir

โ„น๏ธ Minor Interactions

  • Dexamethasone

๐Ÿฝ๏ธ Food Interactions

Fatty meal increases absorption

๐Ÿท Alcohol Interaction

Avoid alcohol; may increase hepatotoxicity risk

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Moderate
Kidney
Low
Heart
Low
Pregnancy
Category C

๐Ÿšซ Contraindications

Hypersensitivity to albendazole, Pregnancy (especially first trimester), Severe hepatic impairment

๐Ÿ“Š Monitoring Parameters

Liver function tests (LFT), Complete blood count (CBC), Renal function tests (RFT)

๐Ÿคฑ Lactation Safety

Excreted in breast milk; use with caution

๐Ÿ’Š Overdose Management

Gastric lavage, activated charcoal, supportive care; monitor hepatic function

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 26, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for a zole 400mg tablet

View All

Alternative brands with exact same active ingredient (Albendazole (400mg)):

Medical Note: Always consult your doctor before switching medications.

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