A fixed-dose combination of a micronized adrenal androgen precursor (DHEA) and a vital mitochondrial coenzyme (CoQ10). DHEA serves as a prohormone for sex steroids, while CoQ10 is essential for cellular energy production and acts as an antioxidant. This combination is primarily used as a nutraceutical supplement to address age-related decline, support energy metabolism, and improve general well-being, particularly in the context of fatigue and suboptimal hormone levels. The micronization of DHEA enhances its dissolution and absorption profile.
Adult: One capsule daily, or as directed by a healthcare practitioner. Typically taken with a meal containing fats to enhance CoQ10 absorption.
Note: Take orally with a main meal (lunch or dinner) that contains dietary fats (e.g., oil, nuts, avocado) to significantly improve the bioavailability of CoQ10. Swallow whole with a glass of water. Do not crush or chew.
DHEA is an endogenous steroid hormone secreted by the adrenal cortex. It acts as a precursor for the synthesis of androgens (testosterone) and estrogens (estradiol) in peripheral tissues, exerting its effects indirectly through these sex steroids. CoQ10 is a fat-soluble, vitamin-like compound located in the inner mitochondrial membrane. It is an essential component of the electron transport chain (Complex I, II, and III) for ATP synthesis and also functions as a potent antioxidant, protecting cell membranes and LDL cholesterol from oxidative damage. The combination aims to support hormonal balance and cellular energy production simultaneously.
Pregnancy: CONTRANDICATED. DHEA is a hormone precursor and may cause virilization of the female fetus. Safety not established.
Driving: Unlikely to affect ability. However, if insomnia or dizziness occurs, caution is advised.
| Warfarin / Acenocoumarol | CoQ10 may have structural similarity to vitamin K and potentially reduce anticoagulant effect, increasing thrombotic risk. | Major |
| Statins (Atorvastatin, Simvastatin) | Statins deplete endogenous CoQ10. Supplementation may reduce statin-associated myopathy. However, DHEA may counteract cholesterol-lowering effects. | Moderate |
| Antipsychotics (e.g., Risperidone) | DHEA may antagonize dopamine receptors, potentially reducing efficacy. | Moderate |
| Antidepressants (SSRIs/SNRIs) | Theoretical risk of serotonin syndrome or mood destabilization; monitor. | Moderate |
| Insulin, Oral Hypoglycemics | DHEA may improve insulin sensitivity, potentially enhancing hypoglycemic effect. | Moderate |
| Tamoxifen, Aromatase Inhibitors | DHEA can be converted to estrogens, potentially antagonizing therapy in hormone-sensitive breast cancer. CONTRAINDICATED. | Major |
| Corticosteroids | May alter adrenal axis function; monitor. | Moderate |
Same composition (Dehydroepiandrosterone (Micronized) (75mg) + Coenzyme Q10 (75mg)), different brands: