Krampoff 360mg Tablet: Complete Guide to Uses, Dosage, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe nausea, vomiting, or diarrhoea that does not stop.
- Difficulty breathing or shortness of breath.
- Irregular heartbeat or palpitations.
- Severe muscle weakness or paralysis.
- Confusion, dizziness, or fainting.
- Swelling of the face, lips, tongue, or throat.
- Blood in stool or vomit.
- Decreased urine output or inability to urinate.
If experiencing severe symptoms, call emergency services immediately.
What is krampoff 360mg tablet used for?
This medicine contains magnesium bisglycinate, a well-absorbed form of magnesium. It is used to treat or prevent low magnesium levels, relieve muscle cramps, support sleep, and promote bone and heart health. The usual adult dose is one 360 mg tablet daily with food, but dosing must be individualized by a doctor.
- Generic Name: Magnesium Bisglycinate (360mg)
- Manufacturer: Jagsonpal Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 krampoff 360mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा मैग्नीशियम बिसग्लाइसिनेट का एक पूरक है, जो शरीर में मैग्नीशियम की कमी को पूरा करने में मदद करता है। मैग्नीशियम मांसपेशियों और तंत्रिकाओं के सामान्य कार्य, हड्डियों की मजबूती, और हृदय की सेहत के लिए आवश्यक है। इसका उपयोग अक्सर मांसपेशियों में ऐंठन, थकान, नींद की समस्या, और माइग्रेन में लाभ के लिए किया जाता है। यह दवा विशेष रूप से उन लोगों के लिए उपयुक्त है जिन्हें अन्य मैग्नीशियम सप्लीमेंट्स से पेट की परेशानी होती है, क्योंकि यह पेट के लिए सौम्य होती है। हालांकि, गुर्दे की गंभीर बीमारी वाले लोगों को इसका सेवन डॉक्टर की सलाह के बिना नहीं करना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में हल्का दस्त, मतली, पेट में ऐंठन, और सुस्ती शामिल हैं। ये आमतौर पर हल्के होते हैं और भोजन के साथ लेने पर कम हो जाते हैं। दुर्लभ मामलों में, अत्यधिक मैग्नीशियम के कारण गंभीर लक्षण जैसे सांस लेने में कठिनाई, अनियमित दिल की धड़कन, और मांसपेशियों में कमजोरी हो सकती है। अगर आपको ऐसे लक्षण दिखें तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी स्वास्थ्य समस्याओं और दवाओं के बारे में बताएं। गुर्दे की बीमारी, हृदय रोग, या गर्भावस्था के दौरान डॉक्टर की सलाह जरूर लें। इस दवा को भोजन के साथ लें ताकि पेट खराब न हो। एंटीबायोटिक्स या बिसफॉस्फोनेट्स के साथ लेते समय कम से कम 2-4 घंटे का अंतर रखें। बच्चों की पहुंच से दूर रखें। अगर कोई गंभीर दुष्प्रभाव दिखे तो तुरंत डॉक्टर से मिलें।
💊 krampoff 360mg tablet Uses & Benefits
[{"condition":"Hypomagnesaemia (low magnesium levels)","description":"This medicine helps to replenish magnesium stores in individuals with confirmed or suspected magnesium deficiency due to inadequate dietary intake, malabsorption, or medication use.","evidence":"Well-established"},{"condition":"Muscle cramps and spasms","description":"Magnesium plays a key role in muscle relaxation; supplementation may reduce the frequency and severity of muscle cramps, especially in athletes or those with low magnesium.","evidence":"Moderate"},{"condition":"Sleep quality improvement","description":"Magnesium may help regulate sleep by supporting GABA function and melatonin production; many users report better sleep with supplementation.","evidence":"Limited"},{"condition":"Migraine prophylaxis","description":"Magnesium supplementation has been studied for migraine prevention and may reduce attack frequency in some individuals.","evidence":"Moderate"},{"condition":"Bone health support","description":"Magnesium is essential for bone mineralization and may contribute to bone density when combined with calcium and vitamin D.","evidence":"Moderate"},{"condition":"Cardiovascular health","description":"Adequate magnesium levels are associated with healthy blood pressure and heart rhythm; supplementation may support cardiovascular function.","evidence":"Limited"}]
Off-label uses: [{"condition":"Premenstrual syndrome (PMS)","description":"Sometimes used to alleviate PMS-related symptoms such as mood swings and cramps, though evidence is limited.","evidence":"Limited"},{"condition":"Anxiety and stress","description":"Magnesium may have a calming effect on the nervous system and is sometimes used as an adjunct for anxiety, but robust clinical evidence is lacking.","evidence":"Limited"},{"condition":"Constipation","description":"Magnesium can draw water into the intestines and loosen stools, but this form is not primarily used for constipation relief.","evidence":"Limited"}]
Primary treatment for: Magnesium deficiency
Also treats: Muscle cramps, Migraine, Insomnia, Osteoporosis, Hypertension
📋 Drug Information
| Generic Name(s) | Magnesium Bisglycinate (360mg) |
| Brand Name | krampoff 360mg tablet |
| Manufacturer | Jagsonpal Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | VITAMINS MINERALS NUTRIENTS |
| Action Class | Minerals |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a cool, dry place. Protect from direct sunlight and moisture. Keep the tablets in their original container with the lid tightly closed. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Magnesium bisglycinate works by delivering magnesium, an essential mineral, directly to the body's cells. Magnesium acts as a cofactor for more than 300 enzymes, including those involved in ATP metabolism, DNA and RNA synthesis, and protein formation. It also regulates calcium and potassium transport across cell membranes, which is critical for nerve impulse conduction, muscle contraction and relaxation, and normal heart rhythm. The glycine component, an inhibitory neurotransmitter, may enhance the calming effects and improve absorption through the intestinal wall. By chelating magnesium with glycine, the compound remains stable in the digestive tract and is absorbed more efficiently than many inorganic magnesium salts, while being less likely to cause osmotic diarrhoea.
Mechanism Steps
💡 How to Take krampoff 360mg tablet
Strength: Each immediate-release tablet contains 360 mg of magnesium bisglycinate, providing elemental magnesium. The exact elemental magnesium content may vary; refer to the product label.
Dosage Information
| Adult Dosage | The typical adult dose of this medicine is one 360 mg tablet taken orally once daily, preferably with a meal to enhance absorption and reduce gastrointestinal upset. However, the exact dose and duration depend on the indication, severity of deficiency, and individual response. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may have reduced renal function and are at higher risk of magnesium accumulation. The dose should be individualized by a clinician, and renal function should be monitored periodically. |
| Renal Impairment | In patients with mild to moderate renal impairment, the dose may need to be reduced. In severe renal impairment (creatinine clearance <30 mL/min), this medicine is contraindicated unless under close medical supervision with monitoring of serum magnesium levels. |
| Hepatic Impairment | No specific dose adjustment is typically required for hepatic impairment, but consult your doctor as a precaution. |
| Maximum Daily Dose | The maximum daily dose should not exceed 360 mg of elemental magnesium from this supplement, unless otherwise directed by a physician. The tolerable upper intake level for supplemental magnesium in adults is 350 mg per day, but this may vary based on medical advice. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of krampoff 360mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Tetracycline antibiotics | Major | |
| Fluoroquinolone antibiotics | Major | |
| Bisphosphonates | Major | |
| Calcium channel blockers | Moderate | |
| Diuretics | Moderate | |
| Proton pump inhibitors | Moderate | |
| Iron supplements | Minor | |
| Zinc supplements | Minor | |
| Alcohol | Moderate | |
| Levothyroxine | Moderate |
🚨 Major Interactions
- Tetracycline antibiotics (e.g., doxycycline, minocycline)
- Fluoroquinolone antibiotics (e.g., ciprofloxacin, levofloxacin)
- Bisphosphonates (e.g., alendronate, risedronate)
⚡ Moderate Interactions
- Calcium channel blockers (e.g., nifedipine, amlodipine)
- Diuretics (e.g., furosemide, hydrochlorothiazide)
- Proton pump inhibitors (e.g., omeprazole, pantoprazole)
🍷 Alcohol Interaction
Alcohol can increase magnesium excretion through the kidneys and may worsen magnesium deficiency. It is advisable to limit or avoid alcohol while taking this medicine, as alcohol may also exacerbate side effects such as drowsiness and gastrointestinal upset.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to magnesium bisglycinate or any inactive ingredients.","Severe renal impairment (e.g., creatinine clearance
⚠️ Warnings & Precautions
["Do not exceed the recommended dose without consulting a healthcare professional.","Use with caution in patients with mild to moderate renal impairment; dose adjustment may be necessary.","Avoid concurrent use with other magnesium-containing products to prevent overdose.","Consult a doctor before use if you are pregnant, planning pregnancy, or breastfeeding.","May cause drowsiness; avoid driving or operating heavy machinery until you know how it affects you.","Separate this medicine from certain antibiotics and bisphosphonates by at least 2-4 hours.","Keep out of reach of children.","If symptoms persist or worsen, consult a doctor."]
🤱 Lactation Safety
Magnesium is excreted in breast milk, but at normal supplemental doses it is considered compatible with breastfeeding. Consult your doctor before using this medicine while nursing.
💊 Overdose Management
Overdose of magnesium bisglycinate can lead to hypermagnesaemia, especially in individuals with kidney impairment. Symptoms include nausea, vomiting, flushing, dizziness, muscle weakness, difficulty breathing, irregular heartbeat, and confusion. In case of suspected overdose, seek immediate medical attention. Treatment may include discontinuation of the supplement, intravenous fluids, and in severe cases, dialysis. Do not attempt to self-treat; contact a poison control center or emergency services.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Before starting this medicine, inform your doctor if you have kidney disease, heart disease, or any other medical condition. Do not exceed the recommended dose without medical advice. Take this medicine with a meal to improve absorption and reduce the chance of stomach upset. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this product. Keep this medicine out of the reach of children. Do not use it after the expiry date printed on the pack. Store it in a cool, dry place away from direct sunlight. If you are scheduled for surgery or dental procedures, tell your healthcare provider that you are taking this medicine. Avoid taking this medicine at the same time as certain antibiotics (such as tetracyclines or fluoroquinolones) or bisphosphonates, as magnesium can reduce their absorption; separate these medicines by at least 2 to 4 hours. Do not use this medicine as a substitute for a varied diet. If you experience persistent diarrhoea, severe abdominal pain, or any signs of an allergic reaction, stop taking it and seek medical help immediately.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly individuals are more likely to have reduced kidney function and may be at higher risk of magnesium accumulation. The dose should be individualized, and periodic monitoring of renal function and serum magnesium is recommended. They may also be more susceptible to drug interactions.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. Magnesium is important for fetal development, but supplementation should be guided by a healthcare provider to ensure appropriate dosing and safety.
🏥 Post-Surgery Considerations
After surgery, inform your surgeon and anesthesiologist that you are taking this medicine. Magnesium can interact with certain anesthetic agents and muscle relaxants. Your doctor may advise temporary discontinuation or dose adjustment.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. Magnesium may interact with certain medications used in dentistry, such as antibiotics. No routine adjustment is usually needed, but your dentist may consult your physician.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause drowsiness in some individuals. Avoid strenuous exercise or activities requiring full alertness until you know how it affects you. If you experience muscle weakness or fatigue, reduce exercise intensity and consult your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness or dizziness in some people. If affected, avoid driving, operating heavy machinery, or performing tasks that require mental alertness. Otherwise, it generally does not interfere with daily activities and may improve energy and sleep quality over time.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor, especially if you are taking it for a diagnosed magnesium deficiency. If you experience severe side effects or suspect an allergic reaction, stop immediately and seek medical help. Your doctor may adjust the dose or recommend an alternative based on your response.
📅 Long-Term Use Effects
Long-term use of this medicine at recommended doses is generally safe. However, prolonged high-dose use can lead to elevated magnesium levels, especially in individuals with kidney disease. Regular monitoring of serum magnesium and renal function may be advised by your doctor. Some people may experience persistent gastrointestinal symptoms. It is important to reassess the need for continued supplementation periodically with your healthcare provider.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Increasing intake of magnesium-rich foods can help maintain normal levels.
Evidence: Well-establishedMagnesium citrate, malate, or taurate may be alternatives if bisglycinate is not suitable.
Evidence: ModerateMagnesium oil or lotions applied to the skin are sometimes used, but evidence for efficacy is limited.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. You can continue taking it before or after vaccination unless your doctor advises otherwise.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription or a letter from your doctor, especially for international travel, to avoid customs issues. Store it in a cool, dry place away from direct sunlight; do not leave it in a hot car. If you are crossing time zones, continue taking your dose at the same time each day as much as possible; if you miss a dose, follow the missed dose instructions. Always pack enough supply for your entire trip plus extra in case of delays.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The onset of effects varies. For muscle cramps, you may notice improvement within a few days to weeks. For sleep or migraine prevention, it may take 2-4 weeks of consistent use. Correction of magnesium deficiency may take several weeks.
A: It is best taken with food to enhance absorption and reduce the risk of stomach upset or diarrhoea.
A: It is generally safe, but avoid taking other magnesium-containing supplements simultaneously to prevent excessive intake. Separate iron or zinc supplements by at least 2 hours.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: You can stop taking it if your doctor advises, but if you have been taking it for a deficiency, consult your doctor before stopping to avoid recurrence of symptoms.
🤔 Common Patient Concerns
🔄 Substitutes for krampoff 360mg tablet
View AllAlternative brands with exact same active ingredient:
-
cramnil tabletKMS Health Center Pvt Ltd ₹80.00 38.5% CHEAPER
-
crampcure 360mg tabletCurewin Pharmaceuticals Ltd ₹85.00 34.6% CHEAPER
-
nocram tabletMedigenesis Pharma Pvt Ltd ₹149.06 14.6% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Magnesium bisglycinate is only for muscle cramps.
Fact: It supports over 300 bodily functions, including nerve, heart, and bone health. - Myth: All magnesium supplements are the same.
Fact: Different forms have varying absorption rates and tolerability; bisglycinate is one of the most bioavailable and gentle forms. - Myth: You can take magnesium without any risk.
Fact: High doses can cause diarrhoea and, in kidney disease, dangerous magnesium accumulation.
🔄 Alternative Options
Generic Alternatives
- Magnesium bisglycinate 360 mg tablet (various manufacturers)
Brand Alternatives
- Krampoff 360mg Tablet