Folic Acid (0.7mg) + Methylcobalamin (2500mcg) + Niacinamide (12mg) + Vitamin C (150mg) (Medical Monograph)

Overview

A fixed-dose combination supplement containing essential B vitamins (Folic Acid, Methylcobalamin, Niacinamide) and Vitamin C. It is primarily indicated for the prevention and treatment of nutritional deficiencies, particularly in high-risk groups like pregnant women, the elderly, and patients with malabsorption syndromes. The combination supports hematopoiesis, neurological function, and cellular metabolism.

Uses

  • Prophylaxis and treatment of nutritional deficiencies of Folic Acid, Vitamin B12, Niacin, and Vitamin C.
  • Supportive therapy in megaloblastic anemia due to Folic Acid and/or Vitamin B12 deficiency.
  • Nutritional support during pregnancy and lactation (Folic Acid for NTD prevention).
  • Peripheral neuropathy management (Methylcobalamin).

Side Effects

  • Nausea
  • Mild gastrointestinal discomfort
  • Headache

Detailed Pharmacology

Folic Acid acts as a coenzyme in one-carbon transfer reactions crucial for DNA/RNA synthesis and amino acid metabolism. Methylcobalamin is a cofactor for methionine synthase (homocysteine metabolism) and methylmalonyl-CoA mutase (myelin synthesis). Niacinamide is a precursor to NAD/NADP, coenzymes for redox reactions. Vitamin C is a potent antioxidant and cofactor for collagen synthesis and neurotransmitter production.

Available Brands in India

BrandManufacturerPrice
Folvite-M Sanofi India Limited ₹120 - ₹180 for 10 tablets strip
Neurobion Forte Merck Limited ₹130 - ₹200 for 10 tablets strip
Becozym-M Forte RPG Life Sciences Ltd ₹100 - ₹160 for 10 tablets strip
Supradyn Nutrition with B-Complex & Minerals Bayer India Limited ₹200 - ₹350 for 15-30 tablets
Folikare-M Eris Lifesciences Ltd ₹110 - ₹170 for 10 tablets strip