Dimethicone (50mg) + Aluminium Hydroxide (250mg) + Milk Of Magnesia (250mg) + Sorbitol (1.25gm) (Medical Monograph)

Overview

A fixed-dose combination antacid, antiflatulent, and laxative agent. Dimethicone acts as an antifoaming agent to relieve gas, aluminium hydroxide and magnesium hydroxide (Milk of Magnesia) neutralize gastric acid, and sorbitol acts as an osmotic laxative to relieve constipation. It is a first-line symptomatic treatment for dyspepsia, hyperacidity, and associated bloating and constipation, commonly used in the Indian OTC market.

1. **Aluminium Hydroxide & Magnesium Hydroxide:** Neutralize secreted gastric hydrochloric acid, raising the gastric pH. This provides symptomatic relief from heartburn and dyspepsia. 2. **Dimethicone:** A physiologically inert silicone polymer with low surface tension. It acts as an antifoaming agent, dispersing and preventing the formation of mucus-enclosed gas pockets in the GI tract, facilitating their expulsion. 3. **Sorbitol:** A hyperosmotic sugar alcohol. It draws water into the intestinal lumen by osmosis, increasing stool water content, softening the stool, and stimulating peristalsis to relieve constipation.