Carboxymethylcellulose (0.5% w/v) + Oxychloro Complex (0.005% w/v) (Medical Monograph)

Overview

A sterile, topical ophthalmic solution combining a high-viscosity ocular lubricant (Carboxymethylcellulose) with a broad-spectrum, preservative-free antimicrobial agent (Oxychloro Complex). It is primarily indicated for the management of dry eye disease (DED) and for the prevention/treatment of ocular surface infections, particularly in contact lens wearers. The combination provides dual-action: lubrication and protection against microbial contamination.

Carboxymethylcellulose (CMC) is an anionic, water-soluble polymer that mimics the mucin layer of the tear film. It increases the viscosity and stability of the pre-corneal tear film, prolonging the breakup time (TBUT), hydrating the ocular surface, and protecting corneal epithelial cells. Oxychloro Complex (OCC), a stabilized form of hypochlorous acid (HOCl), is a potent, naturally occurring antimicrobial oxidant produced by neutrophils. It rapidly oxidizes and denatures proteins, lipids, and nucleic acids of microorganisms (bacteria, viruses, fungi, and acanthamoeba) on contact, disrupting cell membranes and causing microbial death.